Patents by Inventor Gabriela Guimaraes Sousa Leite
Gabriela Guimaraes Sousa Leite has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240366960Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: ApplicationFiled: April 19, 2024Publication date: November 7, 2024Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Publication number: 20240198131Abstract: Mitochondrial antiviral signaling (MA VS) protein mediates innate antiviral responses, and is an important component of the response to severe acute respiratory syndrome coronavirus-2 (SARS-COV-2). Herein methods are provided to increase expression of mitochondrial antiviral signaling (MAVS) protein in epithelial cells by use of a UVA therapy to expose the epithelial cells to the UVA therapy, or to contact a first set of epithelial cells with a second set of epithelial cells which have been exposed to the UVA therapy, or to contact a first set of epithelial cells with the cell lysates of the second set of epithelial cells that have been exposed to the UVA therapy.Type: ApplicationFiled: May 5, 2022Publication date: June 20, 2024Applicant: Cedars-Sinai Medical CenterInventors: Mark Pimentel, Ali Rezaie, Gabriela Guimaraes Sousa Leite, Ruchi Mathur, Gil Y. Melmed
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Patent number: 11992699Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: GrantFiled: March 14, 2022Date of Patent: May 28, 2024Assignee: Cedars-Sinai Medical CenterInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Publication number: 20230147752Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separating a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space and a cooling tube. In some examples, the UV light source is configured to emit light with wavelengths with a desired intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: ApplicationFiled: March 19, 2021Publication date: May 11, 2023Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite, Konstantin Degtyarev, Larry Bischoff, Kuldeep Gandhi, Michael V. Quinn, Richard Cronenberg
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Publication number: 20230038019Abstract: Described herein are compositions and methods of treating gastrointestinal diseases and disorders such as irritable bowel syndrome and small intestinal bacterial overgrowth.Type: ApplicationFiled: March 18, 2020Publication date: February 9, 2023Inventors: Mark PIMENTEL, Gabriela Guimaraes Sousa LEITE, Ruchi MATHUR, Ali REZAIE, Walter MORALES, Stacy WEITSMAN
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Publication number: 20230035292Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: ApplicationFiled: March 14, 2022Publication date: February 2, 2023Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Publication number: 20220186281Abstract: The invention provides for methods and kits for processing viscous biological samples such as intestinal fluids and aspirates. Increased numbers of microorganisms are extracted by the methods and kits of this invention, and thus, DNA extraction and analysis can be performed.Type: ApplicationFiled: January 30, 2020Publication date: June 16, 2022Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Gabriela Guimaraes Sousa Leite, Walter Morales, Stacy Weitsman, Ruchi Mathur, Mark Pimentel
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Patent number: 11318325Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: GrantFiled: October 21, 2021Date of Patent: May 3, 2022Assignee: Cedars-Sinai Medical CenterInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Publication number: 20220040497Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: ApplicationFiled: October 21, 2021Publication date: February 10, 2022Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Patent number: 11179575Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: GrantFiled: August 13, 2020Date of Patent: November 23, 2021Assignee: Cedars-Sinai Medical CenterInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite
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Publication number: 20210106844Abstract: A UV light delivery device for performing intra-corporeal ultraviolet therapy is provided. The device includes an elongated body separated by a proximal end and a distal end. The device also includes a UV light source configured to be received at the receiving space. In some examples, the UV light source is configured to emit light with wavelengths with significant intensity between 320 nm and 410 nm and is utilized in conjunction with an endotracheal tube or a nasopharyngeal airway.Type: ApplicationFiled: August 13, 2020Publication date: April 15, 2021Applicant: CEDARS-SINAI MEDICAL CENTERInventors: Ali Rezaie, Mark Pimentel, Gil Y. Melmed, Ruchi Mathur, Gabriela Guimaraes Sousa Leite