Patents by Inventor Gabriele Di Giacomo

Gabriele Di Giacomo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus and method for micron and submicron particle formation
    Patent number: 7635442
    Abstract: An apparatus is described for micron and submicron particles formation of a substance using the GAS process, comprising a particles formation vessel (22) and means for introducing a solution of the substance and a supercritical fluid into the particles formation vessel (22), wherein said means comprise a nozzle (27) having a central orifice (39) serving to carry a flow of solution, and a plurality of separate outer orifices (41) serving to carry a flow of pure supercritical fluid or a flow of supercritical fluid mixed with a modifier, such that the solvent is extracted from the solution by the supercritical fluid and precipitation of micron and submicron particles occurs. Also a process is described, carried out with such an apparatus.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: December 22, 2009
    Assignee: Dompe Pha.R.MA S.p.A.
    Inventors: Giovanni Del Re, Matteo Putrignano, Gabriele Di Giacomo, Cesare Di Palma
  • APPARATUS AND METHOD FOR MICRON AND SUBMICRON PARTICLE FORMATION
    Publication number: 20080093757
    Abstract: An apparatus is described for micron and submicron particles formation of a substance using the GAS process, comprising a particles formation vessel (22) and means for introducing a solution of the substance and a supercritical fluid into the particles formation vessel (22), wherein said means comprise a nozzle (27) having a central orifice (39) serving to carry a flow of solution, and a plurality of separate outer orifices (41) serving to carry a flow of pure supercritical fluid or a flow of supercritical fluid mixed with a modifier, such that the solvent is extracted from the solution by the supercritical fluid and precipitation of micron and submicron particles occurs. Also a process is described, carried out with such an apparatus.
    Type: Application
    Filed: January 16, 2007
    Publication date: April 24, 2008
    Applicant: DOMPE PHA. R. MA S.P.A.
    Inventors: Giovanni Del Re, Matteo Putrignano, Gabriele Di Giacomo, Cesare Di Palma
  • Apparatus and method for micron and submicron particle formation
    Patent number: 7175886
    Abstract: An apparatus is described for micron and submicron particles formation of a substance using the GAS process, comprising a particles formation vessel (22) and means for introducing a solution of the substance and a supercritical fluid into the particles formation vessel (22), wherein said means comprise a nozzle (27) having a central orifice (39) serving to carry a flow of solution, and a plurality of separate outer orifices (41) serving to carry a flow of pure supercritical fluid or a flow of supercritical fluid mixed with a modifier, such that the solvent is extracted from the solution by the supercritical fluid and precipitation of micron and submicron particles occurs. Also a process is described, carried out with such an apparatus.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: February 13, 2007
    Assignee: Dompe' pha.r.ma S.p.A.
    Inventors: Giovanni Del Re, Matteo Putrignano, Gabriele Di Giacomo, Cesare Di Palma
  • Apparatus and method for micron and submicron particle formation
    Publication number: 20040107901
    Abstract: An apparatus is described for micron and submicron particles formation of a substance using the GAS process, comprising a particles formation vessel (22) and means for introducing a solution of the substance and a supercritical fluid into the particles formation vessel (22), wherein said means comprise a nozzle (27) having a central orifice (39) serving to carry a flow of solution, and a plurality of separate outer orifices (41) serving to carry a flow of pure supercritical fluid or a flow of supercritical fluid mixed with a modifier, such that the solvent is extracted from the solution by the supercritical fluid and precipitation of micron and submicron particles occurs. Also a process is described, carried out with such an apparatus.
    Type: Application
    Filed: January 8, 2004
    Publication date: June 10, 2004
    Inventors: Giovanni Del Re, Matteo Putrignano, Gabriele Di Giacomo, Cesare Di Palma