Patents by Inventor Gabriele Handke

Gabriele Handke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted amidoalkyl uracils and their use as inhibitors of the poly(adp-ribose) synthetase (PARS)
    Patent number: 7125995
    Abstract: This application relates to compounds of formula (I) below in which the several variable groups are as defined in the specification and claims, to methods of preparing these materials, to pharmaceutical compositions containing these materials, and to methods of using these materials to treat ischaemia or reperfusion damage.
    Type: Grant
    Filed: November 2, 2001
    Date of Patent: October 24, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Barbara Albrecht, Michael Gerisch, Gabriele Handke-Ergüden, Axel Jensen, Thomas Krahn, Werner Nickl, Felix Oehme, Karl-Heinz Schlemmer, Henning Steinhagen
  • Thiazolyl amide derivatives
    Patent number: 7105553
    Abstract: The present invention relates to novel compounds, to a process for their preparation and to their use as medicaments, in particular as antiviral medicaments.
    Type: Grant
    Filed: December 12, 2000
    Date of Patent: September 12, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rüdiger Fischer, Gerald Kleymann, Ulrich Betz, Judith Baumeister, Wolfgang Bender, Peter Eckenberg, Gabriele Handke, Martin Hendrix, Kerstin Henninger, Axel Jensen, Jörg Keldenich, Udo Schneider, Olaf Weber
  • Substituted amidoalkyl uracils and their use as inhibitors of the poly(adp-ribose) synthetase (pars)
    Publication number: 20050075347
    Abstract: The invention relates to novel amidoalkyl uracil derivatives of formula (I), to a method for the production thereof, and to their use as medicament active substances for the prophylaxis and/or treatment of medical disorders.
    Type: Application
    Filed: November 2, 2001
    Publication date: April 7, 2005
    Inventors: Barbara Albrecht, Michael Gerisch, Gabriele Handke-Erguden, Axel Jensen, Thomas Krahn, Werner Nickl, Felix Oehme, Karl-Heinz Schlemmer, Henning Steinhagen
  • Thiazolyl amides and their use as antiviral drugs
    Publication number: 20040235916
    Abstract: The invention relates to the novel compounds of formula (I), to a method for producing the same and to their use as drugs, especially as antiviral drugs.
    Type: Application
    Filed: December 19, 2003
    Publication date: November 25, 2004
    Inventors: Rudolf Schohe-Loop, Ulrich Betz, Rudiger Fischer, Martin Hendrix, Gerald Kleymann, Judith Baumeister, Wolfgang Bender, Peter Eckenberg, Gabriele Handke-Erguden, Kerstin Henninger, Axel Jensen, Jorg Keldenich, Udo Schneider, Olaf Weber
  • Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases
    Publication number: 20040235830
    Abstract: The invention relates to substituted cyclohexane derivates of formula (I), a method for the production thereof and the use thereof in medicaments, particularly for preventing and/or treating cardiovascular diseases, diseases of the urogenital tract and cerebrovascular diseases.
    Type: Application
    Filed: April 22, 2004
    Publication date: November 25, 2004
    Inventors: Susanne Rohrig, Andreas Stolle, Julio C. Castro-Palomino, Helmut Haning, Gabriele Handke-Erguden, Noemi Daviu-Folguera, Holger Paulsen, Josef Pernerstorfer, Stephan-Nicholas Wirtz, Henning Steinhagen, Wolfgang Thielemann, Erwin Bischoff, Ulrich Ebbinghaus-Kintscher, Peter Ellinghaus, Joachim Hutter, Thomas Krahn, Frank Wunder, Klemens Lustig, Joachim Schuhmacher, Frank Sussmeier
  • Thiazolyl amide derivatives
    Publication number: 20040006076
    Abstract: The present invention relates to novel compounds, to a process for their preparation and to their use as medicaments, in particular as antiviral medicaments.
    Type: Application
    Filed: November 12, 2002
    Publication date: January 8, 2004
    Inventors: Rudiger Fischer, Gerald Kleymann, Ulrich Betz, Judith Baumeister, Wolfgang Bender, Peter Eckenberg, Gabriele Handke, Martin Hendrix, Kerstin Henninger, Axel Jensen, Jorg Keldenich, Udo Schneider, Olaf Weber
  • Substituted amidoalkyl-uracils and their use
    Patent number: 6649618
    Abstract: Novel amidoalkyl-uracil derivatives of the formula (I) in which A represents 1-3 ring atoms and X represents optionally substituted (C2-C10)alkylene or (C3-C8)cycloalkylene as defined in claim 1, a process for their preparation, and their use as medicaments for the prophylaxis and/or treatment of disorders are described.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: November 18, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Härter, Barbara Albrecht, Michael Gerisch, Gabriele Handke, Joachim Hütter, Axel Jensen, Thomas Krahn, Joachim Mittendorf, Felix Oehme, Karl-Heinz Schlemmer, Henning Steinhagen
  • Substituted amidoalkyl-uracils and their use
    Publication number: 20030022905
    Abstract: Novel amidoalkyl-uracil derivatives of the formula (I) 1
    Type: Application
    Filed: July 16, 2001
    Publication date: January 30, 2003
    Inventors: Michael Harter, Barbara Albrecht, Michael Gerisch, Gabriele Handke, Joachim Hutter, Axel Jensen, Thomas Krahn, Joachim Mittendorf, Felix Oehme, Karl-Heinz Schlemmer, Henning Steinhagen
  • Thiazolyl urea derivatives and their utilization as antiviral agents
    Patent number: 6500817
    Abstract: The present invention relates to thiazolylurea derivatives, a process for their preparation, and their use as pharmaceuticals, in particular as antiviral pharmaceuticals.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: December 31, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rüdiger Fischer, Gerald Kleymann, Judith Baumeister, Wolfgang Bender, Ulrich Betz, Peter Eckenberg, Gabriele Handke, Martin Hendrix, Udo Schneider, Olaf Weber, Kerstin Henninger, Axel Jensen, Jörg Keldenich
  • Uncompetitive inhibitors of helicase-primase
    Publication number: 20020160932
    Abstract: The present invention relates to inhibitors of the viral helicase-primase enzyme complex with anti-herpes activity, and to medicaments containing these compounds in suitable formulation. The invention further describes a method for identifying substances with antiviral activity in order to treat herpes infections in humans and animals.
    Type: Application
    Filed: August 30, 2001
    Publication date: October 31, 2002
    Inventors: Gerald Kleymann, Rudiger Fischer, Martin Hendrix, Guy Hewlett, Veniamin Pevzner, Ulrich Betz, Wolfgang Bender, Peter Eckenberg, Gabriele Handke, Udo Schneider, Olaf Weber, Kerstin Henninger, Axel Jensen, Jorg Keldenich, Judith Baumeister
  • Inverse thiazolylamide derivatives
    Publication number: 20020119995
    Abstract: The present invention relates to novel compounds, i.e. inverse thiazolylamide derivatives, to processes for their preparation and to their use as medicaments, in particular as antiviral medicaments.
    Type: Application
    Filed: July 31, 2001
    Publication date: August 29, 2002
    Inventors: Martin Hendrix, Gerald Kleymann, Ulrich Betz, Judith Baumeister, Wolfgang Bender, Peter Eckenberg, Rudiger Fischer, Gabriele Handke, Kerstin Henninger, Axel Jensen, Jorg Keldenich, Udo Schneider, Olaf Weber
  • 2,4'-bridged bis-2,4-diaminoquinazolines
    Patent number: 5739127
    Abstract: The present invention provides 2,4'-bridged bis-2,4-diaminoquinazolines of the general formula (I): ##STR1## in which the indicated substituents are as defined in the description. The invention also provides a process for the preparation of the compounds of the formula (I), drugs containing said compounds and processes for the preparation of drugs containing said compounds.
    Type: Grant
    Filed: November 8, 1996
    Date of Patent: April 14, 1998
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rudolf Schohe-Loop, Peter-Rudolf Seidel, William Bullock, Gabriele Handke, Achim Feurer, Wolfgang Roben, Georg Terstappen, Joachim Schuhmacher, Franz-Josef van der Staay, Bernard Schmidt, Richard J. Fanelli, Jane C. Chisholm, Richard T. McCarthy