Patents by Inventor Gabriele Kohler

Gabriele Kohler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing dendritic cells, cells thus produced and containers for carrying out this process
    Patent number: 5866115
    Abstract: Dendritic cells are of interest therapeutically as antigen-presenting cells. A process is disclosed in which peripheral blood cells are first isolated and the CD 34 antigen-expressing blood progenitor cells which they contain are then enriched. These enriched cells are expanded ex-vivo using a combination of haematopoietic growth factors and cytokines. Over a period of 10-20 days, they give rise, in particular to dendritic cells which, where appropriate, can be purified still further. These cells are functionally active with regard to the ability to present antigen.
    Type: Grant
    Filed: October 11, 1996
    Date of Patent: February 2, 1999
    Assignee: Klinikum Der Albert-Ludwigs-Universitat Freiburg
    Inventors: Lothar Kanz, Wolfram Brugger, Reinhard Henschler, Gabriele Kohler, Hans-Eckart Schaefer, Albrecht Lindemann, Roland Mertelsmann, Andreas Mackensen, Paul Fisch, Birgit Herbst