Abstract: The present invention concerns a method to prepare and purify the ester glyceryl-tris-(3-hydroxy butyrate) of formula (I) and its optically active isomers, in particular the enantiomer (R, R, R).

Abstract: A method and apparatus are provided for decoding a plurality of codewords from a received binary bitstream. A first decoding stage processes each of the codewords with a first iterative decoding algorithm based on forward error-correction information of the codewords. A second decoding stage processes selected ones of the codewords with a second iterative decoding algorithm, which is based on forward error-correction information in the selected ones of the codewords. Each codeword selected for the second decoding stage is selected in response to an exit from the decoding of that codeword without the production of a decoded codeword. The second iterative decoding algorithm is configured to enable a greater number of iterations of decoding per codeword than the first iterative decoding algorithm.

Abstract: A low-density parity-check (LDPC) decoder comprising a pre-processor, a core decoder, and a post-processor. The pre-processor is configured to transform a received log-likelihood-ratio (LLR) sequence into a form that enables the core decoder to toggle at a reduced rate during iterative decoding processing thereof. Upon stoppage of the decoding processing corresponding to the LLR sequence, the post-processor operates to apply a complementary transformation to the output of the core decoder, which recovers the corresponding codeword of the LDPC code. An example embodiment of the LDPC decoder operating in this manner may be able to beneficially reduce the power consumption therein by about 10%.

Abstract: The present invention concerns a method to prepare and purify the ester glyceryl-tris-(3-hydroxybutyrate) of formula (I): and its optically active isomers, in particular the enantiomer (R, R, R).

Abstract: Processes for the synthesis and purification of glycoconjugate derivatives of cholic acid of formula (I) are provided herein.

Abstract: The present invention relates to a process for the preparation of migalastat of formula (I) and intermediates useful in the synthesis thereof. The process comprises the double reductive amination reaction of a compound of formula (VI).

Abstract: An apparatus, comprising: circuitry configured, in response to receipt of input data, to transmit a stream of symbols of a constellation to a modulator for modulation onto a carrier wherein a frequency of occurrence of symbols in the stream is dependent upon a probability-amplitude distribution for symbols of the constellation, wherein the probability-amplitude distribution has a kurtosis less than a target value and a shape of the probability-amplitude distribution causes low-amplitude symbols to occur more frequently on average in the stream than high-amplitude symbols.

Abstract: Processes for the synthesis and purification of glycoconjugate derivatives of cholic acid are provided herein.

Abstract: The invention relates to a process for preparing a compound of formula (I) in particular obeticholic acid and intermediates suitable for its synthesis.

Abstract: An apparatus, comprising: circuitry configured, in response to receipt of input data, to transmit a stream of symbols of a constellation to a modulator for modulation onto a carrier wherein a frequency of occurrence of symbols in the stream is dependent upon a probability-amplitude distribution for symbols of the constellation, wherein the probability-amplitude distribution has a kurtosis less than a target value and a shape of the probability-amplitude distribution causes low-amplitude symbols to occur more frequently on average in the stream than high-amplitude symbols.

Abstract: An apparatus includes a digital signal processor to perform perturbation-based optical nonlinearity compensation of optical data signals of a communication stream. The digital signal processor includes first digital circuits to calculate multiplicative factors for corrections to the optical data signals from products of values of the optical data signals at a reduced set of times. The reduced set is a down-sampling of the sequence of consecutive symbol times of the communication stream. The digital signal processor also includes second digital circuits to calculate the multiplicative factors for corrections to the optical data signals at the consecutive symbol times by interpolating the multiplicative factors evaluated at the reduced set of times.

Abstract: The invention relates to a process for preparing a compound of formula (I) in particular obeticholic acid and intermediates suitable for its synthesis.

Abstract: The present invention relates to a process for the preparation of migalastat of formula (I) and intermediates useful in the synthesis thereof. The process comprises the reductive amination reaction of a compound of formula (VI).

Abstract: The present invention relates to a process for the preparation of an inhibitor of phosphodiesterase 4, in particular of phosphodiesterase 4B (PDE4B), and intermediates useful for its preparation.

Abstract: The present invention relates to a process for the preparation of selegiline base, an irreversible and selective inhibitor of the MAO-B enzymes and which is used in the treatment of Parkinson's Disease.

Abstract: The present invention relates to a process for the preparation of an inhibitor of phosphodiesterase 4, in particular of phosphodiesterase 4B (PDE4B), and intermediates useful for its preparation.

Abstract: The present invention relates to a process for the preparation of anhydrous crystalline 2-(R)-[(3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl]-1H-benzimidazole (dexlansoprazole).

Abstract: The invention relates to a process for preparing a compound of formula (I) in particular obeticholic acid and intermediates suitable for its synthesis.

Abstract: The present invention relates to a process for the preparation of anhydrous crystalline 2-(R)-[(3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl)methyl)sulfinyl]-1H-benzimidazole (dexlansoprazole).

Abstract: The present invention relates to a process for the preparation of selegiline base, an irreversible and selective inhibitor of the MAO-B enzymes and which is used in the treatment of Parkinson's Disease.