Patents by Inventor Gabriele Schaefer

Gabriele Schaefer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-HER antibodies
    Patent number: 9327035
    Abstract: The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: May 3, 2016
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Lauric Haber, Gabriele Schaefer, Mark X. Sliwkowski
  • NEUREGULIN ANTIBODIES AND USES THEREOF
    Publication number: 20140363438
    Abstract: The invention provides anti-neuregulin1 antibodies and methods of using the antibodies in treating diseases or disorders, such as cancer. In a particular embodiment, the anti-neuregulin1 antibodies bind to both neuregulin1? and neuregulin 1? isoforms.
    Type: Application
    Filed: August 16, 2012
    Publication date: December 11, 2014
    Applicant: Genentech, Inc.
    Inventors: Erica Jackson, Gabriele Schaefer, Yan Wu
  • ANTI-HER ANTIBODIES
    Publication number: 20140193414
    Abstract: The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists.
    Type: Application
    Filed: December 9, 2013
    Publication date: July 10, 2014
    Applicant: Genentech, Inc.
    Inventors: Germaine Fuh, Lauric Haber, Gabriele Schaefer, Mark X. Sliwkowski
  • ANTI-HER ANTIBODIES
    Publication number: 20140056899
    Abstract: The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists.
    Type: Application
    Filed: October 29, 2013
    Publication date: February 27, 2014
    Applicant: GENENTECH, INC.
    Inventors: Germaine Fuh, Lauric Haber, Gabriele Schaefer, Mark X. Sliwkowski
  • Multispecific anti-HER antibodies
    Patent number: 8597652
    Abstract: The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: December 3, 2013
    Assignee: Genentech, Inc.
    Inventors: Germaine Fuh, Lauric Haber, Gabriele Schaefer, Mark X. Sliwkowski
  • ANTI-HER ANTIBODIES
    Publication number: 20100255010
    Abstract: The invention provides anti-HER antibodies, including multispecific anti-HER antibodies, compositions comprising and methods of using these antibodies. Also provided herein are EGFR/HER3 multispecific antibodies that are less toxic than traditional EGFR antagonists.
    Type: Application
    Filed: March 19, 2010
    Publication date: October 7, 2010
    Applicant: Genentech, Inc.
    Inventors: Germaine Fuh, Lauric Haber, Gabriele Schaefer, Mark X. Sliwkowski
  • Gamma-heregulin
    Publication number: 20060029602
    Abstract: A novel member of the heregulin superfamily has been identified which is designated “?-HRG”. This molecule, secreted by human breast cancer MDA-MB-175 cells, leads to the formation of a constitutive active receptor complex and stimulates the growth of these cells in an autocrine manner. ?-HRG polypeptide and nucleic acid are disclosed, together with various uses therefor (e.g. use of ?-HRG nucleic acid for the recombinant production of ?-HRG). ?-HRG antagonists (e.g. neutralizing antibodies and antisense nucleic acid molecules) as well as uses therefor are also described.
    Type: Application
    Filed: July 1, 2005
    Publication date: February 9, 2006
    Applicant: Genentech, Inc.
    Inventors: Gabriele Schaefer, Mark Sliwkowski