Patents by Inventor Gabriele Schuhmann-Giampieri

Gabriele Schuhmann-Giampieri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,4,7,10-tetraazacyclododecane butyltriols, processes for their production and pharmaceutical agents containing them
    Patent number: 5980864
    Abstract: 1,4,7,10-Tetraazacyclodedecane butyltriols of general formula I.sub.A ##STR1## in which R.sup.1 means hydrogen or a metal ion equivalent independent of one another andR.sup.2 means a butyltriol radicalas well as their salts with organic or inorganic bases or amino acids are valuable pharmaceutical agents.
    Type: Grant
    Filed: March 19, 1991
    Date of Patent: November 9, 1999
    Assignee: Schering Aktiengellsellschaft
    Inventors: Johannes Platzek, Heinz Gries, Hanns-Joachim Weinmann, Gabriele Schuhmann-Giampieri, Wolf-Rudiger Press
  • Cascade polymer bound complexing compounds for MRI
    Patent number: 5911971
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Grant
    Filed: November 4, 1996
    Date of Patent: June 15, 1999
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • Macrocyclic polymer complexing agents, their complexes, process for their production and pharmaceutical agents containing these compounds
    Patent number: 5876698
    Abstract: Polymeric compounds of general formula I(M).sub.n A (I)in whichM stands for the radical of a macrocyclic complexing agent,A stands for a backbone molecule, which shows a deficit of n amino groups, n hydroxy groups or n carboxy groups,n stands for the numbers 1 to 400, characterized in thatM, independent of one another, stands for complexing agents of general formula IA ##STR1## in which all variables are defined herein.
    Type: Grant
    Filed: May 11, 1992
    Date of Patent: March 2, 1999
    Assignee: Schering Aktiengesellschaft
    Inventors: Heribert Schmitt-Willich, Johannes Platzek, Heinz Gries, Gabriele Schuhmann-Giampieri, Thomas Frenzel
  • DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production
    Patent number: 5859214
    Abstract: Compounds of general formula I ##STR1## wherein Z.sup.1, Z.sup.2, X, R.sup.2 and R.sup.3 are as herein defined, are valuable pharmaceutical agents. In particular, the compounds are useful as contrast agents in NMR diagnosis.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: January 12, 1999
    Assignee: Schering Aktiengesellshaft
    Inventors: Heinz Gries, Erich Klieger, Bernd Raduchel, Heribert Schmitt-Willich, Hanns-Joachim Weinmann, Hubert Vogler, Gabriele Schuhmann-Giampieri, Jurgen Conrad
  • DTPA monoamides for MRI
    Patent number: 5843399
    Abstract: Chelate compounds of general formula I ##STR1## wherein X is a hydrogen atom and/or a metal ion equivalent of an element of atomic numbers 21-29, 31, 32, 37-40, 42-44, 49 or 57-83, andZ.sup.1, Z.sup.2, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined herein, as well as their salts with inorganic and/or organic bases, amino acids or amino acid amides, are valuable pharmaceutical agents, e.g., for NMR imaging.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 1, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Heinz Gries, Erich Klieger, Bernd Raduchel, Heribert Schmitt-Willich, Hanns-Joachim Weinmann, Hubert Vogler, Gabriele Schuhmann-Giampieri, Jurgen Conrad
  • Iodine-containing peptides
    Patent number: 5756066
    Abstract: Iodine-containing peptides of general formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, a, m and q have the meanings indicated in the description, agents containing these compounds, the use of compounds as contrast media as well as processes for their production are described.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 26, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Danute Nitecki, Werner Krause, Franz-Karl Maier, Gabriele Schuhmann-Giampieri, Wolf-Rudiger Press, Peter Muschick, Sara Biancalana
  • DTPA derivatives substituted in a novel way, their metal complexes, and their use in diagnosis and therapy
    Patent number: 5746995
    Abstract: The invention relates to new diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, that contain an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents that contain these compounds and their use as contrast media and antidotes.
    Type: Grant
    Filed: November 30, 1995
    Date of Patent: May 5, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Franz-Karl Maier, Michael Bauer, Werner Krause, Ulrich Speck, Gabriele Schuhmann-Giampieri, Andreas Muhler, Thomas Balzer, Wolf-Rudiger Press
  • Dimeric DTPA derivatives, their metal complexes and pharmaceutical agents containing these complexes
    Patent number: 5695737
    Abstract: The invention relates to new dimeric DTPA derivatives, their metal complexes, containing at least one ion of an element of atomic numbers 21-32, 37-39, 42-51 and 57-83, agents containing these complexes, their use in NMR diagnosis and/or diagnostic radiology, radiodiagnosis and radiotherapy, as well as process for their production.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 9, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Werner Krause, Franz Karl Maier, Michael Bauer, Gabriele Schuhmann-Giampieri, Wolf Press, Johannes Platzek, Heribert Schmitt-Willich
  • Use of metal complexes as liver and gallbladder X-ray diagnostic agents
    Patent number: 5672335
    Abstract: Metal complexes containing a metal of atomic numbers 39-42, 44-51 or 56-83 and a complexing agent can be used for the production of contrast media for use in the contrast-enhanced computer tomography of the liver and the biliary tracts.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: September 30, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Werner Krause, Thomas Balzer, Wolf-Rudiger Press, Gabriele Schuhmann-Giampieri, Ulrich Speck, Andreas Muhler
  • Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them
    Patent number: 5650136
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: July 22, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • Cascade polymers with iodoaromatic compounds
    Patent number: 5593660
    Abstract: Iodine-containing dendrimeric polymers of general formula IA--(X).sub.b (I),in whichA stands for a nitrogen-containing nucleus of basic multiplicity b, andb stands for the numbers 1 to 8 andX stands for a radical composed of ##EQU1## reproduction units S and at most 2.sup.n imaging radicals Z, in whichn determines the number of generations and stands for the numbers 1 to 10,S and Z have various meanings, are valuable X-ray diagnostic agents.
    Type: Grant
    Filed: December 21, 1994
    Date of Patent: January 14, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Werner Krause, Franz-Karl Maier, Michael Bauer, Gabriele Schuhmann-Giampieri, Wolf-R udiger Press
  • Use of amide complex compounds
    Patent number: 5399340
    Abstract: Complex compounds of general Formula I ##STR1## wherein X is a hydrogen atom and/or a metal ion equivalent of at least one element of atomic numbers 21-29, 42, 44 or 58-70, with at least two of the substituents X representing a metal ion equivalent, andR.sup.1, R.sup.2, R.sup.3, R.sup.4, Y and n are defined herein, as well as their salts with organic and/or inorganic bases, are valuable compounds for organ-specific NMR diagnostics.
    Type: Grant
    Filed: April 20, 1993
    Date of Patent: March 21, 1995
    Assignee: Schering Aktiengesellschaft
    Inventors: Bernd Raduchel, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Jurgen Conrad
  • Cascade polymer bound chelating compounds, their chelates and conjugates, processes for their production, and pharmaceutical agents containing them
    Patent number: 5364614
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Grant
    Filed: November 21, 1990
    Date of Patent: November 15, 1994
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer