Patents by Inventor Gabrijela Dumbovic

Gabrijela Dumbovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Retaining Splicing RNAs in the Nucleus Based on Chemically Modified Antisense Oligonucleotides
    Publication number: 20230257741
    Abstract: The inventive technology relates to systems and methods for the use of chemically modified antisense oligonucleotides (ASOs) to sterically prevent intron excision thus causing nuclear retention of the RNA and inhibiting nuclear export. In preferred therapeutic embodiments, ASOs may be engineered to quarantine clinically relevant RNAs in the nucleus of the cell.
    Type: Application
    Filed: January 29, 2021
    Publication date: August 17, 2023
    Inventors: Gabrijela Dumbovic, John Rinn, Marvin Caruthers, Katarzyna Jastrzebska, Heera K. Langner