Patents by Inventor Gaddam Goud

Gaddam Goud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8444994
    Abstract: A multivalent anthelmintic vaccine targets both hookworm and schistosomiasis. The vaccine includes, at a minimum, a recombinant third-stage larval hookworm antigen, a recombinant adult stage hookworm antigen, and a recombinant schistosome antigen. Preferably, the hookworm antigens are Necator americanus antigens, although antigens from other hookworm species (e.g. Ancylostoma duodenale) may also be employed. The schistosome antigen is preferably a Schistosoma mansoni or a Schistosoma haematobium antigen although antigens from other schistosome species (e.g. Schistosoma japonicum) may also be employed. In some cases full or partial sequences of schistosome antigens may be fused with full or partial sequences of hookworm {Necator americanus) to produce recombinant chimeric antigens.
    Type: Grant
    Filed: June 30, 2009
    Date of Patent: May 21, 2013
    Assignees: The Albert B. Sabin Vaccine Institute, The George Washington University, The Council of the Queensland Institute of Medical Research
    Inventors: Peter Hotez, Alexander Loukas, Mark Pearson, Jeffrey Bethony, Bin Zhan, Gaddam Goud, Maria Elena Bottazzi, David Diemert, Ami Shah Brown, Peter Giacomautonio
  • Patent number: 8211438
    Abstract: A vaccine for human hookworm is provided. The vaccine comprises at least one L3 larval stage antigen (e.g. Na-ASP-2 or Na-SAA-2) and at least one adult stage human hookworm antigen (e.g. Na-APR-1, Na-CP-2, Na-CP-3, Na-CP-4, Na-CP-5, or Na-GST-1) and adjuvants.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: July 3, 2012
    Assignee: The George Washington University
    Inventors: Peter Hotez, Alexander Loukas, Bin Zhan, Gaddam Goud, Jeffrey Bethony, Maria Elena Bottazzi, Aaron Miles
  • Publication number: 20110200640
    Abstract: A multivalent anthelmintic vaccine targets both hookworm and schistosomiasis. The vaccine includes, at a minimum, a recombinant third-stage larval hookworm antigen, a recombinant adult stage hookworm antigen, and a recombinant schistosome antigen. Preferably, the hookworm antigens are Necator americanus antigens, although antigens from other hookworm species (e.g. Ancylostoma duodenale) may also be employed. The schistosome antigen is preferably a Schistosoma mansoni or a Schistosoma haematobium antigen although antigens from other schistosome species (e.g. Schistosoma japonicum) may also be employed. In some cases full or partial sequences of schistosome antigens may be fused with full or partial sequences of hookworm {Necator americanus) to produce recombinant chimeric antigens.
    Type: Application
    Filed: June 30, 2009
    Publication date: August 18, 2011
    Inventors: Peter Hotez, Alexander Loukas, Mark Pearson, Jeffrey Bethony, Bin Zhan, Gaddam Goud, Maria Elena Bottazzi, David Diemert, Ami Shah Brown, Peter Giacomantonio
  • Publication number: 20100003285
    Abstract: A vaccine for human hookworm is provided. The vaccine comprises at least one L3 larval stage antigen (e.g. Na-ASP-2 or Na-SAA-2) and at least one adult stage human hookworm antigen (e.g. Na-APR-1, Na-CP-2, Na-CP-3, Na-CP-4, Na-CP-5, or Na-GST-1) and adjuvants.
    Type: Application
    Filed: June 26, 2009
    Publication date: January 7, 2010
    Inventors: Peter Hotez, Alexander Loukas, Bin Zhan, Gaddam Goud, Jeffrey Bethony, Maria Elena Bottazzi, Aaron Miles
  • Publication number: 20080166377
    Abstract: A vaccine for human hookworm is provided. The vaccine comprises at least one L3 larval stage antigen (e.g. Na-ASP-2 or Na-SAA-2) and at least one adult stage human hookworm antigen (e.g. Na-APR-1, Na-CP-2, Na-CP-3, Na-CP-4, Na-CP-5, or Na-GST-1) and adjuvants.
    Type: Application
    Filed: September 28, 2007
    Publication date: July 10, 2008
    Inventors: Peter Hotez, Alexander Loukas, Bin Zhan, Gaddam Goud, Jeffrey Bethony, Maria Elena Bottazzi, Aaron Miles
  • Patent number: 7303752
    Abstract: Preparations which elicit an immune response to hookworm antigens and which may be utilized as hookworm vaccines are provided. In addition, a method of increasing the effectiveness of vaccinations against infectious diseases in patients infected with hookworm is provided. The method involves chemically treating the hookworm infestation prior to administering the vaccine.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: December 4, 2007
    Assignee: The George Washington University
    Inventors: Peter Hotez, James Ashcom, Mahnaz Bdamchian, Bin Zhan, Yan Wang, John Hawdon, Alexander Loukas, Angela Williamson, Brian Jones, Jeffrey Bethony, Gaddam Goud, Maria Elena Bottazzi, Susana Mendez
  • Publication number: 20050042232
    Abstract: Preparations which elicit an immune response to hookworm antigens and which may be utilized as hookworm vaccines are provided. In addition, a method of increasing the effectiveness of vaccinations against infectious diseases in patients infected with hookworm is provided. The method involves chemically treating the hookworm infestation prior to administering the vaccine.
    Type: Application
    Filed: April 16, 2004
    Publication date: February 24, 2005
    Inventors: Peter Hotez, James Ashcom, Mahnaz Bdamchian, Bin Zhan, Yan Wang, John Hawdon, Alexander Loukas, Angela Williamson, Brian Jones, Jeffrey Bethony, Gaddam Goud, Maria Bottazzi, Susana Mendez