Patents by Inventor Gaddam Reddy
Gaddam Reddy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20070122444Abstract: The present invention relates to methods, compounds, and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses, and is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention also relates to compounds that inhibit smooth muscle proliferation, for example, by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis. This invention also relates to medical devices, such as a stent, comprising a compound or composition of this invention disposed on or within the medical device.Type: ApplicationFiled: August 30, 2006Publication date: May 31, 2007Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Sesha Alluri, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Rama Murali Krishna Reddy, Potlapally Kumar, Gaddam Reddy
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Publication number: 20070117795Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.Type: ApplicationFiled: August 28, 2006Publication date: May 24, 2007Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Krishna Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
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Publication number: 20070111998Abstract: The present invention relates to novel heterocyclic compounds of the general formula (I), as IL-6 inhibitors, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and compositions, their metabolites and prodrugs thereof. The present invention more particularly provides novel heterocyclic compounds of the general formula (I). Also included is a method for treatment of cancer, cancer cachexia and inflammatory diseases including immunological diseases, particularly those mediated by cytokines such as IL-6, through pSTAT3 inhibition, in a mammal comprising administering an effective amount of a compound of formula (I) as described above.Type: ApplicationFiled: October 12, 2006Publication date: May 17, 2007Applicant: ORCHID RESEARCH LABORATORIES, LTD.Inventors: Siripragada Rao, Akella Satya Srinivas, Shikha Rani, Gaddam Reddy, Sriram Rajagopal, Uma Ramachandran, Duddu Sharada, Rajagopalan Nirmala, Velaiah Sivasudar, Lakshmanan Manikandan, Ramachandran Balaji
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Publication number: 20070099874Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.Type: ApplicationFiled: March 26, 2003Publication date: May 3, 2007Applicant: Reddy US Therapeutics, Inc.Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
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Publication number: 20070088043Abstract: The present invention relates to novel compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and compositions. The present invention more particularly provides novel HDAC inhibitors of the general formula (1). Also included is a method for treatment of cancer, psoriasis, proliferative conditions and conditions mediated by HDAC, in a mammal comprising administering an effective amount of a compound of formula (I) as described above.Type: ApplicationFiled: October 17, 2006Publication date: April 19, 2007Applicant: ORCHID RESEARCH LABORATORIES LIMITED.Inventors: Akella Satya Srinivas, Kilambi Narasimhan, Lakshmanan Manikandan, Sriram Rajagopal, Thangapazham Selvakumar, Gaddam Reddy
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Publication number: 20070072876Abstract: The present invention relates to novel compounds of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and compositions, their metabolites and prodrugs thereof. The present invention more particularly relates to novel pyrimidine carboxamides of the general formula (I).Type: ApplicationFiled: September 7, 2006Publication date: March 29, 2007Applicant: ORCHID RESEARCH LABORATORIES LTD.Inventors: Ravikumar Tadiparthi, Venkatesan Parameswaran, Rajib Barik, Gaddam Reddy, Pawan Aggarwal, Sappanimuthu Thirunavukkarasu, Sriram Rajagopal
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Publication number: 20070004729Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.Type: ApplicationFiled: June 20, 2006Publication date: January 4, 2007Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
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Publication number: 20060258641Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.Type: ApplicationFiled: May 25, 2006Publication date: November 16, 2006Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
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Publication number: 20060172984Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.Type: ApplicationFiled: November 22, 2005Publication date: August 3, 2006Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Yeleswarapu Rao, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
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Publication number: 20060141066Abstract: The present invention provides a novel herbal chocolate composed of Tinospora cordifolia, Glycyrrhyza glabra, Adhatoda vasica, Madhuca indica and Cassia occidentalis. The solid or semisolid nutritious composition is rich in protein/mineral fortified with standardized herbs with proven pharmacological activities such as anti-oxidant, anti stress and adaptogenic property and relief the chronic cough and cold.Type: ApplicationFiled: December 28, 2004Publication date: June 29, 2006Inventors: Pushpangadan Palpu, Ajay Rawat, Chandana Rao, Sanjeev Ojha, Gaddam Reddy
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Publication number: 20060141067Abstract: The invention provides a novel herbal preparation useful in treatment of allergy. Formulation(s) comprises of plant preparation or active component of plant extract together with conventional additives to form the oral dosage forms, which includes tablets, capsules and liquid dosage forms viz. syrup and suspension as anti-allergic. Formulation(s) comprises of Tinospora cardifolia, Piper longum, Albizia lebbeck and Curcunla amada. The formulation can be used as solid or liquid or encapsulated as a soft/hard gelatin capsule for easy consumption as solid or liquid dosage forms.Type: ApplicationFiled: December 28, 2004Publication date: June 29, 2006Inventors: Pushpangadan Palpu, Chandana Rao, Ajay Rawat, Sanjeev Ojha, Gaddam Reddy
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Publication number: 20050288341Abstract: Novel diphenyl ether derivatives are provided that exhibit activity useful for reducing glucose, cholesterol, and/or triglyceride levels in plasma, and for treatment of obesity, inflammation, immunological diseases, autoimmune diseases, diabetes and disorders associated with insulin resistance.Type: ApplicationFiled: March 31, 2005Publication date: December 29, 2005Inventors: Bishwajit Nag, Abhijeet Nag, Debendranath Dey, Shiv Agarwal, Partha Neogi, Gaddam Reddy, Sangamesh Badiger, Gajendra Singh, Surendra Pandey, Santhanagopalan Chithra
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Publication number: 20050227983Abstract: The present invention relates to triazine compounds and their analogs and derivatives, and methods and compositions comprising these compounds. The compounds and compositions of this invention are useful for, among other things, treating pathophysiological conditions arising from inflammatory responses, inhibiting or blocking glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells, inhibiting smooth muscle proliferation, treating vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis, and the like.Type: ApplicationFiled: March 24, 2004Publication date: October 13, 2005Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Sesha Alluri, Velagala Venkata Krishna Reddy, Manojit Pal, Jangalgar Reddy, Koteswar Yeleswarapu, Gaddam Reddy, Potlapally Kumar
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Publication number: 20050228176Abstract: An improved process for the purification of tazobactam or its derivatives of the formula (I) wherein R represents hydrogen, C1-C6alkyl, p-methoxybenzyl, o-nitrobenzyl, p-nitrobenzyl, o-chlorobenzyl, benzyl or diphenylmethyl, which comprises the steps of: i) slurrying the compound of formula (I) containing the impurity of the formula (V) using a solvent in the presence or absence of tartaric acid with or without the presence of water at 20-50° C.Type: ApplicationFiled: April 5, 2005Publication date: October 13, 2005Applicant: Orchid Chemicals and Pharmaceuticals Ltd.Inventors: Andrew Gnanaprakasam, Udayampalayam Senthilkumar, Gaddam Reddy
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Publication number: 20050215781Abstract: The present invention relates to novel polymorph of cefdinir represented by formula (I). More particularly, the present invention relates to novel crystalline form (Crystal D) of cefdinir. The present invention also provides a process for the preparation of novel crystalline form (Crystal D) of cefdinir.Type: ApplicationFiled: March 15, 2005Publication date: September 29, 2005Applicant: ORCHID CHEMICALS & PHARMACEUTICALS LTD.Inventors: Ramasubbu Chandrasekaran, Krishnan Senthilkumar, Saravan Murugan, Venkatasubba Sangaraju, Gaddam Reddy
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Publication number: 20050137196Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.Type: ApplicationFiled: September 27, 2004Publication date: June 23, 2005Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Krishna Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Kumar, Gaddam Reddy
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Publication number: 20050124619Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.Type: ApplicationFiled: September 27, 2004Publication date: June 9, 2005Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Krisha Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Kumar, Gaddam Reddy
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Publication number: 20050113341Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.Type: ApplicationFiled: September 27, 2004Publication date: May 26, 2005Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Murali Krishna Reddy, Bhatlapenumarthy Sridevi, Potlapally Kumar, Gaddam Reddy
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Patent number: 6809445Abstract: A cover for an electric motor including at least one lead wire. The cover includes an inner face, an outer face, and at least one opening extending therebetween. The opening is defined by a perimeter including at least one groove extending between the inner face and the outer face.Type: GrantFiled: April 4, 2002Date of Patent: October 26, 2004Assignee: General Electric CompanyInventor: Gaddam Reddy
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Publication number: 20030189381Abstract: A cover for an electric motor including at least one lead wire. The cover includes an inner face, an outer face, and at least one opening extending therebetween. The opening is defined by a perimeter including at least one groove extending between the inner face and the outer face.Type: ApplicationFiled: April 4, 2002Publication date: October 9, 2003Inventor: Gaddam Reddy