Abstract: An exemplary embodiment of system, method, and computer accessible medium for magnetic resonance spectroscopic imaging for improving signal-to-noise ratio per unit time and optimizing duty cycle in MRSI and/or for reducing chemical-shift artifacts can be provided. In one exemplary embodiment, an excitation pulse can be forwarded to the target and acquiring a signal from the target by multiplexing in time and space. The multiplexing procedure in time can involve (i) a segmentation of a field of view of the at least one portion of the target into a predetermined number of slabs that are acquired sequentially during each repetition time, and/or (ii) an acquisition of multiple voxels. Data can be generated based on the acquired signal. According to another exemplary embodiment, an excitation pulse can be provided to the target, and a signal can be acquired from the target. The excitation pulse can be a series of cascaded Hadamard pulse components. Data can be generated based on the acquired signal.

Abstract: An exemplary embodiment of system, method, and computer accessible medium for magnetic resonance spectroscopic imaging for improving signal-to-noise ratio per unit time and optimizing duty cycle in MRSI and/or for reducing chemical-shift artifacts can be provided. One exemplary embodiment includes forwarding an excitation pulse to the target and acquiring a signal from the target by multiplexing in time and space. Multiplexing in time may involve segmenting a field of view of the at least one portion of the target into a predetermined number of slabs that are acquired sequentially during each repetition time. Multiplexing in space may involve acquiring multiple voxels. Data may be generated based on the acquired signal. A further exemplary embodiment includes providing an excitation pulse to the target and acquiring a signal from the target. The excitation pulse can be a series of cascaded Hadamard pulse components. Data may be generated based on the acquires signal.

Abstract: A method of imaging of an object. A plurality of image datasets, for example a real part and an imaginary part of a magnetic resonance image, are acquired, and are transformed separately to a transform space and filtered. The filtered datasets are inverse transformed and recombined nonlinearly to produce the final image. The preferred transformation is a wavelet transformation. Noisy transform coefficients are suppressed by thresholding.

Abstract: Acquisition of three-dimensional image-guided localized proton spectroscopy (.sup.1 H-MRS) in the human brain is achieved on a standard clinical imager with a hybrid of chemical shift imaging (CSI) and transverse Hadamard spectroscopic imaging (HSI). 16.times.16.times.4 arrays of 3.5 and 1 ml voxels were obtained in 27 minutes. The spatially-selective HSI 90.degree. pulses were incorporated naturally into a PRESS double spin-echo sequence to subdivide the VOI into 4 partitions along its short axis. Two-dimensional CSI is performed along the other long axes. Because the hybrid excites the spins in the entire VOI, a .sqroot.N signal-to-noise-ratio (SNR) gain per given examination time is realized compared to sequentially interleaving N two-dimensional slices. A twofold gain in sensitivity is demonstrated in the brain for N=4.