Patents by Inventor Gaetano Clavenna

Gaetano Clavenna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (R)-2-(3-benzoylphenyl) propionic acid salts and pharmaceutical preparations containing them
    Patent number: 6069172
    Abstract: A new use of the enantiomer (R)-ketoprofen and of its salts with suitable organic and inorganic bases in the therapy of neutrophil-dependent diseases and phlogistic processes is described as well as pharmaceutical preparations containing such compounds and useful for oral, parenteral or topical administration.
    Type: Grant
    Filed: January 27, 1999
    Date of Patent: May 30, 2000
    Assignee: Dompe' SpA
    Inventors: Riccardo Bertini, Cinzia Bizzarri, Laura Brandolini, Gabriella Melillo, Gianfranco Caselli, Gaetano Clavenna
  • Geminal carboxylic acids and esters thereof pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism
    Patent number: 5908863
    Abstract: Compounds of formula I: ##STR1## wherein R.sub.a, R.sub.b, .PHI., B and R are as defined in the disclosure, have antagonistic activity on osteoclast hyper-reactivity.
    Type: Grant
    Filed: February 26, 1997
    Date of Patent: June 1, 1999
    Assignee: Dompe' S.p.A.
    Inventors: Marcello Allegretti, Marco Mantovanini, Gianfranco Caselli, Simonetta Fiorentino, Gaetano Clavenna, Carmelo A. Gandolfi
  • Parenteral pharmaceutical compositions containing ammoniomalkyl salts of 2-arylpropionic acids
    Patent number: 5895789
    Abstract: A pharmaceutical composition for parenteral administration having anti-inflammatory and analgesic properties is disclosed which contain, as the active principle, alkylammonium salts of 2-arylpropionic acids.
    Type: Grant
    Filed: August 27, 1997
    Date of Patent: April 20, 1999
    Assignee: Dompe' SpA
    Inventors: Marco Gentile, Luigi Boltri, Gaetano Clavenna
  • Pharmaceutical formulations in form of thixotropic gel
    Patent number: 5858330
    Abstract: The present invention relates to a topical formulation of gel-like consistency, but nebulizable by a mechanical pump, containing colloidal silices as gelifying agent.
    Type: Grant
    Filed: March 18, 1996
    Date of Patent: January 12, 1999
    Assignee: Dompe' S.p.A.
    Inventors: Luigi Boltri, Antonietta Coppola, Marco Gentile, Gaetano Clavenna
  • Salts of 2-(3-benzoylphenyl) propionic acid with organic bases and pharmaceutical compositions thereof
    Patent number: 5808069
    Abstract: The salts of S(+) 2-(3-benzoylphenyl)propionic acid and of R(-) 2-(3-benzoylphenyl)propionic acid with an organic base such as D-lysine, L-lysine, L-arginine, (R) 3-(4-phenylpiperazin-1-yl)propane-1,2-diol and (S) 3-(4-phenylpiperazin-1-yl)propane-1,2-diol, the process for their preparation and the corresponding pharmaceutical compositions containing said salts are described.
    Type: Grant
    Filed: October 31, 1995
    Date of Patent: September 15, 1998
    Assignees: Dompe' Farmaceutici SpA, Dimpe' SpA
    Inventors: Enrico Bosone, Gaetano Clavenna, Carmelo Gandolfi, Marco Mantovanini, Roberto Curti
  • Tartronic acids, their acetalic ethers and o-esters
    Patent number: 5773465
    Abstract: Tartronic acid acetalic ethers and esters of the general formula: ##STR1## are provided and are useful in treatment of bone dysmetabolism. As examples, Ra and Rb may be hydrogen, B is a C.sub.2 -C.sub.12 acyl group, R is phenyl and n is 0-12.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: June 30, 1998
    Assignee: Dompe Farmaceutici S.p.A.
    Inventors: Carmelo A. Gandolfi, Lorella Cotini, Marco Mantovanini, Gianfranco Caselli, Gaetano Clavenna, Claudio Omini
  • Tartronic acids, their acetalic ethers and O-esters
    Patent number: 5656656
    Abstract: Tartronic acid acetalic ethers and esters of the general formula: ##STR1## are provided and are useful in treatment of bone dysmetabolism. As examples, Ra and Rb may be hydrogen, B is a C.sub.2 -C.sub.12 acyl group, R is phenyl and n is 0-12.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: August 12, 1997
    Assignee: Dompe Farmaceutici S.p.A.
    Inventors: Carmelo A. Gandolfi, Lorella Cotini, Marco Mantovanini, Gianfranco Caselli, Gaetano Clavenna, Claudio Omini
  • Method of reducing subcutaneous inflammation by the topical application of a hydrophilic pharmaceutical composition containing ketoprofen lysine salt
    Patent number: 5618516
    Abstract: A hydrophile pharmaceutical composition in the form of foam is described which contains as active ingredient Ketoprofen lysine salt having a concentration between 10 and 20% p/volume of solution which allows, for topic treatment, the maximum absorption of the active principle. The foam is applied for the local treatment in painful and phlogistic conditions, of rheumatic or traumatic nature, of the articulations, of the musles, of the tendons and of the ligaments.
    Type: Grant
    Filed: March 25, 1996
    Date of Patent: April 8, 1997
    Assignee: Domp e Farmaceutici SpA
    Inventors: Gaetano Clavenna, Giorgio Poletti
  • Hydrophilic pharmaceutical composition containing ketoprofen lysine salt for topical use
    Patent number: 5614171
    Abstract: A hydrophile pharmaceutical composition in the form of foam is described which contains as active ingredient Ketoprofen lysine salt having a concentration between 10 and 20% p/volume of solution which allows, for topic treatment, the maximum absorption of the active principle.The foam is applied for the local treatment in painful and phlogistic conditions, of rheumatic or traumatic nature, of the articulations, of the musles, of the tendons and of the ligaments.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: March 25, 1997
    Assignee: Domp e Farmaceutici SpA
    Inventors: Gaetano Clavenna, Giorgio Poletti
  • Use of fenpyramin as platelet-antiaggregating, vasodilating, antithrombotic and antianginous medicine
    Patent number: 4614744
    Abstract: A new use of N-(4'-pyridyl)-3,3-diphenylpropyl amine, known as fenpyramin, as platelet aggregation-inhibiting medicine and antithrombotic agent as well as vasodilating and antianginous medicine is described.
    Type: Grant
    Filed: July 17, 1984
    Date of Patent: September 30, 1986
    Assignee: RBS Pharma (Roger Bellon Schoum) S.p.A.
    Inventors: Piero Bellani, Gaetano Clavenna, Rinaldo Pellegrini
  • Imidazopyridine compounds
    Patent number: 4594421
    Abstract: New imidazopyridine derivatives are described, having the following formula: ##STR1## wherein R represents a hydrogen atom, an alkyl radical of 1 to 3 carbon atoms, a methoxy group or a halogen atom,R.sub.1 represents a hydrogen atom, an alkyl radical of 1 to 3 carbon atoms,n represents an integer of 1 to 10,X represents a non-toxic pharmaceutically acceptable ion, which possess a skeletal muscle paralyzing activity.
    Type: Grant
    Filed: January 31, 1985
    Date of Patent: June 10, 1986
    Assignee: RBS Pharma (Roger Bellon Schoum) S.p.A.
    Inventors: Piero Bellani, Gaetano Clavenna, Alberta Sosio, Rinaldo Pellegrini
  • Pharmaceutically active ursolic acid derivative
    Patent number: 4530934
    Abstract: There are described a new pharmaceutically active derivative of ursolic acid, 3.beta.-(3-carboxypropionyloxy)ursa-9(11),12-dien-28-oic acid, which possesses activity as an anti-ulcer and anti-viral agent, pharmaceutically acceptable, non-toxic salts thereof, a method of preparing the same and compositions containing the same.
    Type: Grant
    Filed: July 25, 1983
    Date of Patent: July 23, 1985
    Assignee: I.S.F. Spa
    Inventors: Gaetano Clavenna, Carlo Farina, Mario Pinza, Giorgio Pifferi