Patents by Inventor Gagani Athauda

Gagani Athauda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRODUCTION OF SCHWANN CELLS
    Publication number: 20220154142
    Abstract: The invention provides a method of producing a population of human Schwann cells. The method comprises (a) incubating human fascicles with one or more mitogens for a priming period of three to fourteen days to produce primed fascicles, (b) incubating the primed fascicles with one or more tissue dissociation enzymes to produce primed Schwann cells, (c) culturing the primed Schwann cells at an initial Po density for a period of time to achieve no greater than 90% confluence, (d) expanding the population of Schwann cells by culturing the Schwann cells at an initial passage density for a period of time to achieve no greater than 90% confluence for at least two passages, and harvesting the population of human Schwann cells. The invention further provides an isolated population of Schwann cells obtained by the method described herein. In various aspects of the invention, the isolated population is provided in a composition.
    Type: Application
    Filed: February 2, 2022
    Publication date: May 19, 2022
    Inventors: Dalton Dietrich, Gagani Athauda, Mary Bunge, James Guest, Allan Levi, Damien Pearse, Patrick Wood, Aisha Khan
  • PRODUCTION OF SCHWANN CELLS
    Publication number: 20190055515
    Abstract: The invention provides a method of producing a population of human Schwann cells. The method comprises (a) incubating human fascicles with one or more mitogens for a priming period of three to fourteen days to produce primed fascicles, (b) incubating the primed fascicles with one or more tissue dissociation enzymes to produce primed Schwann cells, (c) culturing the primed Schwann cells at an initial Po density for a period of time to achieve no greater than 90% confluence, (d) expanding the population of Schwann cells by culturing the Schwann cells at an initial passage density for a period of time to achieve no greater than 90% confluence for at least two passages, and harvesting the population of human Schwann cells. The invention further provides an isolated population of Schwann cells obtained by the method described herein. In various aspects of the invention, the isolated population is provided in a composition.
    Type: Application
    Filed: February 24, 2017
    Publication date: February 21, 2019
    Inventors: Dalton Dietrich, Gagani Athauda, Mary Bunge, James Guest, Allan Levi, Damien Pearse, Patrick Wood
  • Compositions and methods for inhibition of hepatocyte growth factor receptor c-Met signaling
    Patent number: 8754081
    Abstract: Derivatives and analogs of inhibitors of receptor tyrosine kinase c-Met, pharmaceutical compositions containing derivatives and analogs of c-Met inhibitors are provided. Methods of making derivatives and analogs of c-Met inhibitors and methods of use thereof are provided.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: June 17, 2014
    Assignee: The United States of America as represented by the Secretary, Departmnet of Health and Human Services
    Inventors: Donald P. Bottaro, Megan Peach, Marc Nicklaus, Terrence Burke, Jr., Gagani Athauda, Sarah Choyke, Alessio Giubellino, Nelly Tan, Zhen-Dan Shi
  • Methods for diagnosing and monitoring the progression of cancer by measuring soluble c-Met ectodomain
    Patent number: 8304199
    Abstract: Methods for measuring c-Met levels in urine and blood samples are provided. Methods for diagnosis and prognosis evaluation for cancer are also provided.
    Type: Grant
    Filed: March 22, 2011
    Date of Patent: November 6, 2012
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Amgen, Inc.
    Inventors: Donald P. Bottaro, Gagani Athauda, Teresa Lynn Burgess
  • Methods For Diagnosing And Monitoring The Progression Of Cancer
    Publication number: 20110287450
    Abstract: Methods for measuring c-Met levels in urine and blood samples are provided. Methods for diagnosis and prognosis evaluation for cancer are also provided.
    Type: Application
    Filed: March 22, 2011
    Publication date: November 24, 2011
    Applicants: Amgen, Inc., The United States of America, as represented by the Secretary, Dept. of Health & Human Service
    Inventors: Donald P. Bottaro, Gagani Athauda, Teresa Lynn Burgess
  • COMPOSITIONS AND METHODS FOR INHIBITION OF HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET SIGNALING
    Publication number: 20110190295
    Abstract: Derivatives and analogs of inhibitors of receptor tyrosine kinase c-Met, pharmaceutical compositions containing derivatives and analogs of c-Met inhibitors are provided. Methods of making derivatives and analogs of c-Met inhibitors and methods of use thereof are provided.
    Type: Application
    Filed: March 31, 2009
    Publication date: August 4, 2011
    Applicant: The Govt of the U.S.A., as rep.by the Sec.Dept of Hlth. and Human Svcs., Natl Institutes of Health
    Inventors: Donald P. Bottaro, Megan Peach, Marc Nicklaus, Terrence Burke, JR., Gagani Athauda, Sarah Choyke, Alessio Giubellino, Nelly Tan, Zhen-Dan Shi
  • Methods for diagnosing and monitoring the progression of cancer
    Patent number: 7964365
    Abstract: Methods for measuring c-Met levels in urine and blood samples are provided. Methods for diagnosis and prognosis evaluation for cancer are also provided.
    Type: Grant
    Filed: November 8, 2006
    Date of Patent: June 21, 2011
    Assignees: The United States of Americam as represented by the Secretary, Department of Health and Human Services, Amgen, Inc.
    Inventors: Donald P. Bottaro, Gagani Athauda, Teresa Lynn Burgess