Patents by Inventor Gail Walkinshaw

Gail Walkinshaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF MITOCHONDRIAL DISEASES
    Publication number: 20160324823
    Abstract: The invention relates the method of treatment or amelioration of mitochondrial disorders such as Alzheimer's disease, Parkinson's disease, Friedreich's ataxia (FRDA), cerebellar ataxias, Leber's hereditary optic neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), Myoclonic Epilepsy with Ragged Red Fibers (MERFF), amyotrophic lateral sclerosis (ALS), motor neuron diseases, Huntington's disease, macular degeneration, and epilepsy, with chroman derivatives of Formula I or Formula II as described herein.
    Type: Application
    Filed: June 22, 2016
    Publication date: November 10, 2016
    Inventors: Gail WALKINSHAW, Sekhar BODDUPALLI, Bing WANG, Guy M. MILLER
  • METHODS FOR TREATING ANEMIA
    Publication number: 20150126620
    Abstract: The present invention relates to improved methods and compounds for treating anemia. Screening methods to identify agents for use in these treatment methods are also provided.
    Type: Application
    Filed: August 16, 2012
    Publication date: May 7, 2015
    Applicant: FibroGen, Inc.
    Inventors: Thomas B. Neff, David Liu, Gail Walkinshaw, Marja Johanna Myllyharju, Kari Ilkka Kivirikko, Peppi Leena Elina Karppinen
  • Chroman derivatives
    Patent number: 8791155
    Abstract: The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondria) disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: July 29, 2014
    Assignee: Edison Pharmaceuticals, Inc.
    Inventors: Bing Wang, Gail Walkinshaw, Donald R. James
  • TREATMENT OF MITOCHONDRIAL DISEASES
    Publication number: 20130267538
    Abstract: The invention relates the method of treatment or amelioration of mitochondrial disorders such as Alzheimer's disease, Parkinson's disease, Friedreich's ataxia (FRDA), cerebellar ataxias, Leber's hereditary optic neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), Myoclonic Epilepsy with Ragged Red Fibers (MERFF), amyotrophic lateral sclerosis (ALS), motor neuron diseases, Huntington's disease, macular degeneration, and epilepsy, with chroman derivatives of Formula I or Formula II as described herein.
    Type: Application
    Filed: April 24, 2013
    Publication date: October 10, 2013
    Inventors: Gail WALKINSHAW, Sekhar BODDUPALLI, Bing WANG, Guy M. MILLER
  • CHROMAN DERIVATIVES
    Publication number: 20120088783
    Abstract: The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondria) disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Application
    Filed: September 26, 2011
    Publication date: April 12, 2012
    Applicant: Ampere Life Sciences, Inc.
    Inventors: Bing WANG, Gail Walkinshaw, Donald R. James
  • METHODS FOR TREATMENT OF MULTIPLE SCLEROSIS
    Publication number: 20110263642
    Abstract: The present invention relates to methods and compounds useful for treating multiple sclerosis.
    Type: Application
    Filed: August 26, 2009
    Publication date: October 27, 2011
    Applicant: FibroGen, Inc.
    Inventors: Stephen J. Klaus, Thomas B. Neff, Gail Walkinshaw
  • Furanone derivatives
    Patent number: 7985771
    Abstract: The invention relates to a method of treating with furanone derivatives and the pharmaceutically acceptable salts thereof, one or more conditions of the skin, in particular regulating skin condition, regulating signs of skin aging, treating a number of conditions such as contact dermatitis, skin irritation, rosacea, acne, psoriasis, and preventing and protecting skin tissue against age-related damage or damage resulting from insults such as harmful (UV) radiation or environmental pollution, stress and fatigue.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: July 26, 2011
    Assignee: Monsanto Technology LLC
    Inventors: Sekhar Boddupalli, Gail Walkinshaw, Bing Wang
  • 7,8-bicycloakyl-chroman derivatives
    Patent number: 7875607
    Abstract: 7,8-Bicyclic-chroman derivatives of Formula I: wherein the substituents are defined as in the specification or the pharmaceutically acceptable salts thereof, are disclosed. They are useful for the treatment of inflammatory disorders, neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: January 25, 2011
    Assignee: Ampere Life Sciences, Inc.
    Inventors: Bing Wang, Gail Walkinshaw
  • 7,8-BICYCLOAKYL-CHROMAN DERIVATIVES
    Publication number: 20090170814
    Abstract: 7,8-Bicyclic-chroman derivatives of Formula I: wherein the substituents are defined as in the specification or the pharmaceutically acceptable salts thereof, are disclosed. They are useful for the treatment of inflammatory disorders, neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Application
    Filed: November 24, 2008
    Publication date: July 2, 2009
    Applicant: Edison Pharmaceuticals, inc.
    Inventors: Bing Wang, Gail Walkinshaw
  • Chroman derivatives
    Patent number: 7514461
    Abstract: The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: April 7, 2009
    Assignee: Edison Pharmaceuticals, Inc.
    Inventors: Bing Wang, Gail Walkinshaw, Sekhar Boddupalli, Arkadij M. Elizarov, Xianming Jin, Xianfeng Li, Donald R. James, Jiangao Song, Jian Chen, Wei Zhang
  • 7,8-bicycloalkyl-chroman derivatives
    Patent number: 7470798
    Abstract: 7,8-Bicyclic-chroman derivatives of Formula I: wherein the substituents are defined as in the specification or the pharmaceutically acceptable salts thereof, are disclosed. They are useful for the treatment of inflammatory disorders, neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Grant
    Filed: September 15, 2004
    Date of Patent: December 30, 2008
    Assignee: Edison Pharmaceuticals, Inc.
    Inventors: Bing Wang, Gail Walkinshaw, Jian Chen, Xianming Jin, Jiangao Song, Wei Zhang
  • Benzofuran derivatives
    Patent number: 7078541
    Abstract: Certain benzofuran derivatives are useful in the treatment of certain ischemic or inflammatory conditions, as well as neuroinflammation, neurodegeneration or degenerative diseases in which mitochondrial dysfunction leads to tissue degeneration. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Grant
    Filed: September 17, 2003
    Date of Patent: July 18, 2006
    Assignee: Galileo Pharmaceuticals, Inc.
    Inventors: Sekhar Boddupalli, Gail Walkinshaw, Bing Wang
  • 7,8-Bicycloalkyl-chroman derivatives
    Publication number: 20050065149
    Abstract: 7,8-Bicyclic-chroman derivatives of Formula I: wherein the substituents are defined as in the specification or the pharmaceutically acceptable salts thereof, are disclosed. They are useful for the treatment of inflammatory disorders, neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Application
    Filed: September 15, 2004
    Publication date: March 24, 2005
    Inventors: Bing Wang, Gail Walkinshaw, Jian Chen, Xianming Jin, Jiangao Song, Wei Zhang
  • Treatment of mitochondrial diseases
    Publication number: 20050065099
    Abstract: The invention relates the method of treatment or amelioration of mitochondrial disorders such as Alzheimer's disease, Parkinson's disease, Friedreich's ataxia (FRDA), cerebellar ataxias, Leber's hereditary optic neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), Myoclonic Epilepsy with Ragged Red Fibers (MERFF), amyotrophic lateral sclerosis (ALS), motor neuron diseases, Huntington's disease, macular degeneration, and epilepsy, with chroman derivatives of Formula I or Formula II as described herein.
    Type: Application
    Filed: September 15, 2004
    Publication date: March 24, 2005
    Inventors: Gail Walkinshaw, Sekhar Bodupalli, Bing Wang, Guy Miller
  • Chroman derivatives
    Publication number: 20050065150
    Abstract: The invention relates to novel chroman derivatives, stereoisomers and pharmaceutically acceptable salts of Formula I wherein the substituents are as defined in the specification. They are useful in the treatment of disorders mediated by lipoxygenase, such as immune diseases, respiratory diseases and cardiovascular diseases, as well as in the treatment of neurodegenerative disorders and/or mitochondrial disorders. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Application
    Filed: September 15, 2004
    Publication date: March 24, 2005
    Inventors: Bing Wang, Gail Walkinshaw, Sekhar Boddupalli, Arkadij Elizarov, Xianming Jin, Xianfeng Li, Donald James, Jiangao Song, Jian Chen, Wei Zhang
  • Benzofuran derivatives
    Publication number: 20040063975
    Abstract: Certain benzofuran derivatives are useful in the treatment of certain ischemic or inflammatory conditions, as well as neuroinflammation, neurodegeneration or degenerative diseases in which mitochondrial dysfunction leads to tissue degeneration. They are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Application
    Filed: September 17, 2003
    Publication date: April 1, 2004
    Inventors: Sekhar Boddupalli, Gail Walkinshaw, Bing Wang
  • Furanone derivatives
    Publication number: 20040029812
    Abstract: The invention relates to a method of treating with furanone derivatives and the phmaceutically acceptable salts therof, one or more conditions of the skin, in particular regulating skin condition, regulating signs of skin aging, treating a number of conditions suchas contact dermatitis, skin irritation, rosacea, acne, psoriasis, and preventing and protecting skin tissue against age-related damage or damage resulting from insults such as harmful (UV) radiation or environmental pollution, stress and fatigue.
    Type: Application
    Filed: July 30, 2003
    Publication date: February 12, 2004
    Inventors: Sekhar Boddupalli, Gail Walkinshaw, Bing Wang
  • Furanone derivatives
    Patent number: 6667330
    Abstract: Furanone derivatives and the pharmaceutically acceptable salts thereof have cytoprotective activity and protective activity for neuroinflammation, and neurodegenerative disorders; they are useful in the treatment of stroke, cerebral ischemia, myocardial infarction, myocardial ischemia, chronic heart failure, inflammation and other oxidative stress-related conditions, as well as Alzheimer's disease and senile dementia; they are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Grant
    Filed: January 28, 2003
    Date of Patent: December 23, 2003
    Assignee: Galileo Pharmaceuticals, Inc.
    Inventors: Bing Wang, Wei Zhang, Jiangao Song, Ughetta del Balzo, Lesley Brown, Gail Walkinshaw
  • Furanone derivatives
    Publication number: 20030176361
    Abstract: Furanone derivatives and the pharmaceutically acceptable salts thereof have cytoprotective activity and protective activity for neuroinflammation, and neurodegenerative disorders; they are useful in the treatment of stroke, cerebral ischemia, myocardial infarction, myocardial ischemia, chronic heart failure, inflammation and other oxidative stress-related conditions, as well as Alzheimer's disease and senile dementia; they are also useful in the manufacture of pharmaceutical formulations for the treatment of such conditions.
    Type: Application
    Filed: January 28, 2003
    Publication date: September 18, 2003
    Inventors: Bing Wang, Wei Zhang, Jiangao Song, Ughetta del Balzo, Lesley Brown, Gail Walkinshaw