Abstract: While detecting a cardiac arrhythmia, a mapping electrode of a probe is used to associate a local activation time with a first location in a region of interest in the heart. While detecting an absence of the cardiac arrhythmia, the local activation time is associated with a second location in the heart. Electrical data of the first location is assigned to the second location, and an electroanatomic map of the heart is generated that includes the second location in association with the assigned electrical data of the first location.

Abstract: A method includes receiving a position of an intra-body probe inserted into an organ of a living body in a first coordinate system. Fluoroscopic images of the body are received. A movement of the body in the fluoroscopic images is measured in a second coordinate system. The received position of the intra-body probe in the first coordinate system is corrected using the movement identified in the second coordinate system.

Abstract: A method for mapping abnormal electrical activity, including obtaining electrical signal data from respective locations in a heart of a living subject, and automatically analyzing the signal data to identify complex fractionated electrograms (CFEs) therein. The method further includes analyzing the CFEs so as to identify reentry locations comprised in the respective locations, and displaying information derived from the identification in relation to a map of the heart.

Abstract: A method, including measuring values of a physical parameter at multiple locations in an organ of a subject, and analyzing the measured values to identify a range of the values, including at least one sub-range containing one or more values that were not measured. The method further includes receiving a selection from a user of a value in the sub-range, and, responsive to the selection, displaying a candidate location for further measurement.

Abstract: An endobronchial probe includes a deflector having a bore extending therethrough at an angle to its long axis for passage of a tool. The probe includes a location sensor and an ultrasound imager. A push-pull anchoring system comprises a plurality of guides and wires that can extend beyond the guides and retract within the guides. When extended the wires diverge from the long axis sufficiently to engage a bronchus. The probe includes a balloon disposed on the distal segment contralateral to bore that when inflated urges the mouth of the bore into contact with the bronchial wall.

Abstract: Methods and systems for mapping cardiac electrical activity employ a cardiac catheter having a plurality of spines mounted at the distal end, each spine having a plurality of electrodes. Electrical signal data are obtained from the heart via the electrodes, and respective intracardiac locations and orientations of the spines are sensed. An electroanatomic map of the heart is derived from the signal data, and presented as a graphic representation of the respective intracardiac locations and orientations of the spines, with distinctive graphical indicia of at least portions of the spines. The method is further carried out by displaying the electroanatomic map, and responsively to the displayed electroanatomic map, adjusting at least one of the locations and orientations of at least one of the spines.

Abstract: A method for characterizing an electrocardiogram, including receiving a first unipolar signal from a first location of a heart and a second unipolar signal from a second location of the heart. The method further includes generating a bipolar signal from the first and second unipolar signals, and analyzing the bipolar signal to delineate a time period during which the first and second locations generate a bipolar complex. The method also includes analyzing the first unipolar signal within the time period to determine an activation time of the first location.

Abstract: A method for mapping abnormal electrical activity, including obtaining electrical signal data from respective locations in a heart of a living subject, and automatically analyzing the signal data to identify complex fractionated electrograms (CFEs) therein. The method further includes analyzing the CFEs so as to identify reentry locations comprised in the respective locations, and displaying information derived from the identification in relation to a map of the heart.

Abstract: A method, including measuring values of a physical parameter at multiple locations in an organ of a subject, and analyzing the measured values to identify a range of the values, including at least one sub-range containing one or more values that were not measured. The method further includes receiving a selection from a user of a value in the sub-range, and, responsive to the selection, displaying a candidate location for further measurement.

Abstract: Software and apparatus are provided to automatically detect and map ganglionated plexi that are found within areas of complex fractionated electrograms in cardiac chambers. Electrogram signal are analyzed to count the number of complexes whose amplitude and peak-to-peak intervals meet certain criteria. Functional maps indicating a spatial distribution of the ganglionated plexi and the relative numbers of complex fractionated electrograms are produced for display.

Abstract: A method for imaging includes receiving a first three-dimensional (3D) image of a vicinity of an organ within a body of a subject and creating a geometrical model of a tubular structure in the first 3D image in the vicinity of the organ. An invasive probe is inserted into the organ, and a second 3D image containing the organ is captured using the invasive probe. One or more points are located on a surface of the tubular structure using the invasive probe, and the second 3D image is registered with the first 3D image by matching the one or more points to the geometrical model.

Abstract: Methods and systems are provided for locating arrhythmogenic cardiac focus. A training set of electrical signal data is acquired and automatically analyzed to identify CFAE locations. The data representing the CFAE locations are and subjected to determinations of medical significance, such as ablation decisions, by a battery of physicians. The decisions and descriptive statistics of the data are fitted to a binary logistic mixed model, in which the physician decisions are treated as random effects. The model is then applied to patient CFAE data to establish estimates of medical significance, such as suitability for ablation.

Abstract: Methods and systems are provided for locating arrhythmogenic cardiac focus. A training set of electrical signal data is acquired and automatically analyzed to identify CFAE locations. The data representing the CFAE locations are and subjected to determinations of medical significance, such as ablation decisions, by a battery of physicians. The decisions and descriptive statistics of the data are fitted to a binary logistic mixed model, in which the physician decisions are treated as random effects. The model is then applied to patient CFAE data to establish estimates of medical significance, such as suitability for ablation.

Abstract: Software and apparatus are provided to automatically detect and map ganglionated plexi that are found within areas of complex fractionated electrograms in cardiac chambers. Electrogram signal are analyzed to count the number of complexes whose amplitude and peak-to-peak intervals meet certain criteria. Functional maps indicating a spatial distribution of the ganglionated plexi and the relative numbers of complex fractionated electrograms are produced for display.

Abstract: A method for imaging includes receiving a first three-dimensional (3D) image of a vicinity of an organ within a body of a subject and creating a geometrical model of a tubular structure in the first 3D image in the vicinity of the organ. An invasive probe is inserted into the organ, and a second 3D image containing the organ is captured using the invasive probe. One or more points are located on a surface of the tubular structure using the invasive probe, and the second 3D image is registered with the first 3D image by matching the one or more points to the geometrical model.

Abstract: The invention relates to a device and to a method for visual assistance during the electrophysiological use of a catheter in the heart, enabling electroanatomic 3D mapping data relating to an area of the heart to be treated to be visualised during the use of the catheter. Before the catheter is used, 3D image data of a body region containing the area to be treated is detected by means of a method for tomographic 3D imaging. The area to be treated or significant parts thereof are extracted from said 3D image data, in order to obtain selected 3D image data. The electroanatomic 3D mapping data and the selected 3D image data obtained are then classed in terms of position and dimension, and are adjacently visualised, for example, during the catheter ablation. The inventive method and associated device enable the orientation of the operator to be improved during the use of a catheter in the heart.

Abstract: A method and a device are disclosed for visually supporting an electrophysiology catheter application in the heart, whereby electroanatomical 3D mapping data of an area of the heart to be treated which are provided during performance of the catheter application are visualized. Before the catheter application is carried out, 3D image data of the area to be treated are recorded by way of a tomographical 3D imaging method, a 3D surface profile of objects in the area to be treated is extracted from the 3D image data by segmentation and the electroanatomical 3D mapping data provided and the 3D images representing the 3D surface profile are associated with each other in the correct position and dimension relative each other and e.g. visualized in a superimposed manner during the catheter application. The disclosed method and the corresponding device allow for an improved orientation of the user who carries out an electrophysiology catheter application in the heart.