Abstract: Aspects of the subject matter described herein relate to stream operators. In aspects, a stream event is received. Based on a timestamp associated with the stream event and the number of stream operators that have asked to be activated prior to or at the timestamp, zero or more stream objects are informed of one or more time events and torn down if no longer needed. In addition, a destination stream operator is instantiated, if needed, data (e.g., the timestamp and packet, if any) corresponding to the stream event is provided to a stream operator, output data, if any, is received from the stream operator, and the stream operator is torn down if it no longer needs state data between invocations.

Abstract: Aspects of the subject matter described herein relate to stream operators. In aspects, a stream event is received. Based on a timestamp associated with the stream event and the number of stream operators that have asked to be activated prior to or at the timestamp, zero or more stream objects are informed of one or more time events and torn down if no longer needed. In addition, a destination stream operator is instantiated, if needed, data (e.g., the timestamp and packet, if any) corresponding to the stream event is provided to a stream operator, output data, if any, is received from the stream operator, and the stream operator is torn down if it no longer needs state data between invocations.

Abstract: Disclosed are consensus optical contig maps of an entire genome of an organism and methods of using the maps to verify, validate, refute and/or access the accuracy of a known nucleic acid sequence or full genomic sequence. The maps are constructed using optical methods wherein DNA is elongated and fixed along their length onto a solid planar surface so that the DNA molecules are individually analyzable and accessible for enzymatic reactions. The DNA molecules are then reacted with a restriction enzyme to yield cleaved fragments of discernable length fixed to the surface. The lengths of the fragments are then determined, using optical methods. From the lengths determined, an optical contig map is assembled and can be compared to a corresponding known sequence, for example, a genomic sequence.