Abstract: The current application relates to an optimization procedure where the noise reduction strength is incrementally increased and applied in the noise reduction scheme. A non-linear quantitative map is then computed followed by the quantitative bias estimation. The optimization conditions are then checked and the noise reduction “strength” is increased if the bias difference is higher than a predefined threshold.

Abstract: A method includes obtaining contrast enhanced perfusion imaging data of at least two vessel regions, one downstream from the other, and at least one tissue of interest, which receives blood from the circulatory system, of a scanned subject. The method further includes determining a blood flow time difference between contrast material peaks of the at least two vessel regions based on the image data. The method further includes determining an absolute perfusion of the tissue of interest based on the image data. The method further includes computing a standardized perfusion value based on the absolute perfusion and the time difference. The method further includes displaying the standardized perfusion value.

Abstract: The current application relates to an optimization procedure where the noise reduction strength is incrementally increased and applied in the noise reduction scheme. A non-linear quantitative map is then computed followed by the quantitative bias estimation. The optimization conditions are then checked and the noise reduction “strength” is increased if the bias difference is higher than a predefined threshold.

Abstract: An imaging system includes a radiation source (110) that emits radiation that traverses an examination region and a detector (116) that detects radiation traversing the examination region and a subject disposed therein, and produces a signal indicative of the energy of the detected radiation. A data selector (122) energy discriminates the signal based on an energy spectra setting corresponding to first and second spectral characteristics of a contrast agent administered to the subject, wherein the contrast agent has a first attenuation spectral characteristic when attached to the target and a second different spectral characteristic when not attached to the target. A reconstructor (134) reconstructs the signal based on the first and second spectral characteristics and generates volumetric image data indicative of the target.

Abstract: A method includes obtaining image data that includes contrast enhanced spectral image data from a contrast enhanced spectral volume scan of a subject. The method further includes obtaining images that include a set of localized dynamic contrast enhanced images from a localized dynamic contrast enhanced series scan of the subject. The method further includes determining a fluid volume map based on the image data and the images. A computing system includes a computer readable storage medium with computer readable instructions for a fluid volume map determiner. The instructions determine a volumetric fluid volume map based on contrast enhanced spectral volume image data from a contrast enhanced spectral volume scan and a set of localized dynamic contrast enhanced images from a localized dynamic contrast enhanced series scan. The computing system further includes a processor that implements the instructions and determines the volumetric fluid volume map.

Abstract: A method includes obtaining contrast enhanced perfusion imaging data of at least two vessel regions, one downstream from the other, and at least one tissue of interest, which receives blood from the circulatory system, of a scanned subject. The method further includes determining a blood flow time difference between contrast material peaks of the at least two vessel regions based on the image data. The method further includes determining an absolute perfusion of the tissue of interest based on the image data. The method further includes computing a standardized perfusion value based on the absolute perfusion and the time difference. The method further includes displaying the standardized perfusion value.

Abstract: An imaging system includes a radiation source (110) that emits radiation that traverses an examination region and a detector (116) that detects radiation traversing the examination region and a subject disposed therein, and produces a signal indicative of the energy of the detected radiation. A data selector (122) energy discriminates the signal based on an energy spectra setting corresponding to first and second spectral characteristics of a contrast agent administered to the subject, wherein the contrast agent has a first attenuation spectral characteristic when attached to the target and a second different spectral characteristic when not attached to the target. A reconstructor (134) reconstructs the signal based on the first and second spectral characteristics and generates volumetric image data indicative of the target.