Patents by Inventor Ganapati G. Bhat

Ganapati G. Bhat has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR PRODUCING A 1,5-BENZOTHIAZEPIN COMPOUND
    Publication number: 20220315547
    Abstract: The present invention relates to a process for the preparation of a compound of formula (I) comprising: reacting a compound of formula (II) with a compound of formula (III) in the presence of a triazine compound to obtain a compound of formula (IV), and deprotecting said compound of formula (IV) to obtain the compound of formula (I). The compound of formula (I) can be prepared by the process according to the present invention in high yields and high purity. In addition, the process according to the present invention does not use a large amount of solvents or require a purification process of intermediate compounds.
    Type: Application
    Filed: August 27, 2020
    Publication date: October 6, 2022
    Inventors: Shinya Kiguchi, Ganapati G. Bhat, Johnson M. Coutinho, Mikael DAHLSTROM, Michael Lofthagen, Akinori Tatara
  • Process for the preparation of 1,5-benzothiazepine compounds
    Patent number: 10995115
    Abstract: The present invention relates to a process for the preparation of certain 1,5-benzothiazepine compounds, and in particular to a process for the preparation of elobixibat. The process can be carried out under mild and safe conditions and may be used to prepare elobixibat on an industrial scale. The invention also relates to a process for the preparation of a crystalline monohydrate of elobixibat.
    Type: Grant
    Filed: August 20, 2019
    Date of Patent: May 4, 2021
    Assignee: Elobix AB
    Inventors: Ganapati G. Bhat, Johnson M. Coutinho, Mikael Dahlström, Michael Lofthagen, Akinori Tatara
  • PROCESS FOR THE PREPARATION OF 1,5-BENZOTHIAZEPINE COMPOUNDS
    Publication number: 20200109165
    Abstract: The present invention relates to a process for the preparation of certain 1,5-benzothiazepine compounds, and in particular to a process for the preparation of elobixibat. The process can be carried out under mild and safe conditions and may be used to prepare elobixibat on an industrial scale. The invention also relates to a process for the preparation of a crystalline monohydrate of elobixibat.
    Type: Application
    Filed: August 20, 2019
    Publication date: April 9, 2020
    Inventors: Ganapati G. Bhat, Johnson M. Coutinho, Mikael Dahlström, Michael Lofthagen, Akinori Tatara
  • Process for the preparation of 1,5-benzothiazepine compounds
    Patent number: 10428109
    Abstract: The present invention relates to a process for the preparation of certain 1,5-benzothiazepine compounds, and in particular to a process for the preparation of elobixibat. The process can be carried out under mild and safe conditions and may be used to prepare elobixibat on an industrial scale. The invention also relates to a process for the preparation of a crystalline monohydrate of elobixibat.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: October 1, 2019
    Assignee: Elobix AB
    Inventors: Ganapati G. Bhat, Johnson M. Coutinho, Mikael Dahlström, Michael Lofthagen, Akinori Tatara
  • PROCESS FOR THE PREPARATION OF 1,5-BENZOTHIAZEPINE COMPOUNDS
    Publication number: 20190276493
    Abstract: The present invention relates to a process for the preparation of certain 1,5-benzothiazepine compounds, and in particular to a process for the preparation of elobixibat. The process can be carried out under mild and safe conditions and may be used to prepare elobixibat on an industrial scale. The invention also relates to a process for the preparation of a crystalline monohydrate of elobixibat.
    Type: Application
    Filed: March 29, 2019
    Publication date: September 12, 2019
    Inventors: Ganapati G. Bhat, Johnson M. Coutinho, Mikael Dahlström, Michael Lofthagen, Akinori Tatara