Patents by Inventor Ganapati Reddy Pamulapati

Ganapati Reddy Pamulapati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF SUBSTITUTED TRICYCLIC AMIDES AND ANALOGUES THEREOF
    Publication number: 20240327419
    Abstract: The present disclosure includes synthetic methods for preparing certain substituted tricyclic amides, which can be used to treat, ameliorate, and/or prevent hepatitis B virus (HBV) and/or hepatitis D virus (HDV) infections in a subject.
    Type: Application
    Filed: July 15, 2022
    Publication date: October 3, 2024
    Inventors: Jeremy Mason, Mahesh Pallerla, Ganapati Reddy Pamulapati
  • SYNTHETIC PROCESSES AND INTERMEDIATES
    Publication number: 20230113948
    Abstract: The invention provides synthetic processes and synthetic intermediate compounds that can be used to prepare therapeutic conjugates. The invention also provides methods for treating HBV and/or HDV infection in a human by administering a therapeutic conjugate prepared by the synthetic methods of the invention.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 13, 2023
    Applicant: ARBUTUS BIOPHARMA CORPORATION
    Inventors: Mahesh PALLERLA, Ganapati Reddy PAMULAPATI, Jan SPINK
  • Methods for preparing substituted pyridinone-containing tricyclic compounds
    Patent number: 11505551
    Abstract: The present disclosure relates to novel, scalable methods of making substituted tricyclic compounds that are useful to treat and/or prevent HBV and/or HBV-HDV infection and related conditions in a subject.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: November 22, 2022
    Assignee: Arbutus Biopharma Corporation
    Inventors: Shuai Chen, Bruce D. Dorsey, Dimitar B. Gotchev, Duyan Nguyen, Mahesh Kumar Pallerla, Ganapati Reddy Pamulapati
  • Processes for preparing antiviral compounds
    Patent number: 11192875
    Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
    Type: Grant
    Filed: January 16, 2020
    Date of Patent: December 7, 2021
    Assignee: Gilead Pharmasset LLC
    Inventors: Kevin M. Allan, Shinji Fujimori, Lars V. Heumann, Grace May, Katie Ann Brown, Christopher M. Levins, Ganapati Reddy Pamulapati, Benjamin James Roberts, Keshab Sarma, Martin Gerald Teresk, Xiang Wang, Scott Alan Wolckenhauer
  • METHODS FOR PREPARING SUBSTITUTED PYRIDINONE-CONTAINING TRICYCLIC COMPOUNDS
    Publication number: 20210032246
    Abstract: The present disclosure relates to novel, scalable methods of making substituted tricyclic compounds that are useful to treat and/or prevent HBV and/or HBV-HDV infection and related conditions in a subject.
    Type: Application
    Filed: April 11, 2019
    Publication date: February 4, 2021
    Inventors: Shuai Chen, Bruce D. Dorsey, Dimitar B. Gotchev, Duyan Nguyen, Mahesh Kumar Pallerla, Ganapati Reddy Pamulapati
  • PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS
    Publication number: 20200392100
    Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
    Type: Application
    Filed: January 16, 2020
    Publication date: December 17, 2020
    Inventors: Kevin M. Allan, Shinji Fujimori, Lars V. Heumann, Grace May, Katie Ann Brown, Christopher M. Levins, Ganapati Reddy Pamulapati, Benjamin James Roberts, Keshab Sarma, Martin Gerald Teresk, Xiang Wang, Scott Alan Wolckenhauer
  • Processes for preparing antiviral compounds
    Patent number: 10584109
    Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: March 10, 2020
    Assignee: Gillead Pharmasset LLC
    Inventors: Kevin M. Allan, Shinji Fujimori, Lars V. Heumann, Grace May, Katie Ann Brown, Christopher M. Levins, Ganapati Reddy Pamulapati, Benjamin James Roberts, Keshab Sarma, Martin Gerald Teresk, Xiang Wang, Scott Alan Wolckenhauer
  • PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS
    Publication number: 20190263771
    Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
    Type: Application
    Filed: May 6, 2019
    Publication date: August 29, 2019
    Inventors: Kevin M. Allan, Shinji Fujimori, Lars V. Heumann, Grace May, Katie Ann Brown, Christopher M. Levins, Ganapati Reddy Pamulapati, Benjamin James Roberts, Keshab Sarma, Martin Gerald Teresk, Xiang Wang, Scott Alan Wolckenhauer
  • PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS
    Publication number: 20180179175
    Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
    Type: Application
    Filed: December 19, 2017
    Publication date: June 28, 2018
    Inventors: Kevin M. Allan, Shinji Fujimori, Lars V. Heumann, Grace May Huynh, Katie Ann Keaton, Christopher M. Levins, Ganapati Reddy Pamulapati, Benjamin James Roberts, Keshab Sarma, Martin Gerald Teresk, Xiang Wang, Scott Alan Wolckenhauer
  • NUCLEOSIDE PHOSPHORAMIDATES
    Publication number: 20180044367
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent 5 RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Application
    Filed: March 28, 2017
    Publication date: February 15, 2018
    Inventors: Byoung-Kwon Chun, Ganapati Reddy Pamulapati, Suguna Rachakonda, Bruce Ross, Michael Joseph Sofia, Peiyuan Wang, Hai-Ren Zhang
  • Processes for preparing antiviral compounds
    Patent number: 9890134
    Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: February 13, 2018
    Assignee: Gilead Pharmasset LLC
    Inventors: Kevin M. Allan, Shinji Fujimori, Lars V. Heumann, Grace May Huynh, Katie Ann Keaton, Chrisopher M. Levins, Ganapati Reddy Pamulapati, Benjamin James Roberts, Keshab Sarma, Martin Gerald Teresk, Xiang Wang, Scott Alan Wolckenhauer
  • PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS
    Publication number: 20170283390
    Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
    Type: Application
    Filed: April 28, 2017
    Publication date: October 5, 2017
    Inventors: Kevin M. Allan, Shinji Fujimori, Lars V. Heumann, Grace May Huynh, Katie Ann Keaton, Christopher M. Levins, Ganapati Reddy Pamulapati, Benjamin James Roberts, Keshab Sarma, Martin Gerald Teresk, Xiang Wang, Scott Alan Wolckenhauer
  • Processes for preparing antiviral compounds
    Patent number: 9670187
    Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
    Type: Grant
    Filed: June 8, 2015
    Date of Patent: June 6, 2017
    Assignee: GILEAD PHARMASSET LLC
    Inventors: Kevin M. Allan, Shinji Fujimori, Lars V. Heumann, Grace May Huynh, Katie Ann Keaton, Christopher M. Levins, Ganapati Reddy Pamulapati, Benjamin James Roberts, Keshab Sarma, Martin Gerald Teresk, Xiang Wang, Scott Alan Wolckenhauer
  • Nucleoside phosphoramidates
    Patent number: 9637512
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent 5 RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: May 2, 2017
    Assignee: Gilead Pharmasset LLC
    Inventors: Byoung-Kwon Chun, Ganapati Reddy Pamulapati, Suguna Rachakonda, Bruce Ross, Michael Joseph Sofia, Peiyuan Wang, Hai-Ren Zhang
  • NUCLEOSIDE PHOSPHORAMIDATES
    Publication number: 20160354400
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Application
    Filed: February 5, 2016
    Publication date: December 8, 2016
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • Nucleoside phosphoramidates
    Patent number: 9284342
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Grant
    Filed: June 24, 2013
    Date of Patent: March 15, 2016
    Assignee: Gilead Pharmasset LLC
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • PROCESSES FOR PREPARING ANTIVIRAL COMPOUNDS
    Publication number: 20150361073
    Abstract: The present disclosure provides processes for the preparation of a compound of formula: which is useful as an antiviral agent. The disclosure also provides compounds that are synthetic intermediates.
    Type: Application
    Filed: June 8, 2015
    Publication date: December 17, 2015
    Inventors: Kevin M. Allan, Shinji Fujimori, Lars V. Heumann, Grace May Huynh, Katie Ann Keaton, Christopher M. Levins, Ganapati Reddy Pamulapati, Benjamin James Roberts, Keshab Sarma, Martin Gerald Teresk, Xiang Wang, Scott Alan Wolckenhauer
  • Nucleoside phosphoramidates
    Patent number: 9206217
    Abstract: Disclosed herein are nucleoside phosphoramidates and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent 5 RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.
    Type: Grant
    Filed: January 2, 2013
    Date of Patent: December 8, 2015
    Assignee: Gilead Pharmasset LLC
    Inventors: Bruce Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang, Byoung-Kwon Chun, Peiyuan Wang
  • Synthesis of purine nucleosides
    Patent number: 9045520
    Abstract: A process for preparing phosphoramidate prodrugs or cyclic phosphate prodrugs of nucleoside derivatives, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: June 2, 2015
    Assignee: GILEAD PHARMASSET LLC
    Inventors: Byoung-Kwon Chun, Jinfa Du, Suguna Rachakonda, Bruce Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Wonsuk Chang, Hai-Ren Zhang, Dhanpalan Nagarathnam
  • Stereoselective synthesis of phosphorus containing actives
    Patent number: 8859756
    Abstract: Disclosed herein are phosphorus-containing actives, their use as actives for treating diseases, and a stereoselective process for preparing the same. Also disclosed herein are useful synthetic intermediates and processes for preparing the same.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: October 14, 2014
    Assignee: Gilead Pharmasset LLC
    Inventors: Bruce S. Ross, Michael Joseph Sofia, Ganapati Reddy Pamulapati, Suguna Rachakonda, Hai-Ren Zhang