Patents by Inventor Ganesh Devidas Mahale

Ganesh Devidas Mahale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Industrial preparation of 11-[4-{2-(2-hydroxyethoxy) ethyl}-1-piperazinyl] dibenzo [b,f]-[1,4]thiazepine
    Patent number: 7847094
    Abstract: Disclosed herein is an industrial preparation of Quetiapine by the reaction of 11-piperazinyldibenzo[b,f][1,4]-thiazepine or its salt with 2-(2-chloroethoxy)ethanol in presence of an organic or inorganic base under neat or aqueous condition to form 11-[4-{2-(2-hydroxyethoxy)ethyl}-1-piperazinyl]dibenzo[b,f]-[1,4]thiazepine. The quetiapine free base obtained is further converted to its hemi-fumarate salt.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: December 7, 2010
    Assignee: IPCA Laboratories Limited
    Inventors: Ashok Kumar, Dharmendra Singh, Swapnali Hemant Patil, Ganesh Devidas Mahale, Uttamrao Arjunrao Sawant, Balasaheb Ganpat Jadhav, Ragneshkumar Rana
  • Process for preparation of highly pure isotretinoin
    Patent number: 7763748
    Abstract: The present invention relates to a process for preparation of isotretinoin and more specifically, to a purification process for obtaining highly pure isotretinoin that is useful as a keratolytic agent, particularly useful for the treatment of acne. The process involves treating isotretinoin containing metal contamination and/or other impurities with a base in a suitable solvent to form a solution of isotretinoin, followed by adsorption, precipiation, and filtration or centrifugation.
    Type: Grant
    Filed: February 20, 2008
    Date of Patent: July 27, 2010
    Assignee: IPCA Laboratories Limited
    Inventors: Ashok Kumar, Dharmendra Singh, Ganesh Devidas Mahale, Ragnesh Kumar Rana, Mahesh Kharade
  • Manufacturing process for methyl phenidate and intermediates thereof
    Patent number: 7459467
    Abstract: The present invention discloses selective and complete reduction of pyridine ring in a biaryl system comprising ?-substituted or non-substituted benzene ring and relates more specifically, not exclusively, for the manufacture of methylphenidate, which is used for treatment of Attention Deficit Hyperactive Disorder (ADHD) and also acts as central nervous system stimulant, by using palladium/C in a solvent such as C1-C4 alcohols in presence of molar quantities of organic and/or inorganic acids.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: December 2, 2008
    Assignee: IPCA Laboratories, Ltd.
    Inventors: Ashok Kumar, Dharmendra Singh, Swapnali Hemant Patil, Ganesh Devidas Mahale, Uttamrao Arjunrao Sawant
  • PROCESS FOR PREPARATION OF HIGHLY PURE ISOTRETINOIN
    Publication number: 20080207946
    Abstract: The present invention relates to a process for preparation of isotretinoin and more specifically, to a purification process for obtaining highly pure isotretinoin that is useful as a keratolytic agent, particularly useful for the treatment of acne.
    Type: Application
    Filed: February 20, 2008
    Publication date: August 28, 2008
    Inventors: Ashok Kumar, Dharmendra Singh, Ganesh Devidas Mahale, Ragnesh Kumar Rana, Mahesh Kharade