Abstract: A data storage method, apparatus, and device, and a readable storage medium. The method includes: after a random access memory is powered on, obtaining target data to be stored in a fixed storage address of the random access memory; determining a target transmission mode from a bit value change transmission mode and a bit value fixed transmission mode, wherein the target transmission mode is different from a historical transmission mode determined after the random access memory is powered on last time; and transmitting the target data from and to the random access memory according to the target transmission mode. The method can prevent data from being stolen after power-down of the target data, and guarantees the data security.

Abstract: The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TR? mutation.

Abstract: Provided are an image data storage method, an image data processing method and system, and a related apparatus. The image data processing method includes the following steps: sequentially storing image data in a dynamic random memory according to a preset storage format, so that adjacent pieces of image data in the dynamic random memory have continuous storage addresses; reading a preset number of pieces of multi-channel parallel image data from the dynamic random memory, and storing the multi-channel parallel image data in a first-in first-out memory of an FPGA; and executing a convolution operation on target image data in the first-in first-out memory to obtain image feature data. By means of the method, the image data processing rate can be increased.

Abstract: A system for accelerating an RNN network including: a first cache, which is used for outputting Wx1 to WxN or Wh1 to WhN in parallel in N paths in a cyclic switching manner, and the degree of parallelism is k; a second cache, which is used for outputting xt or ht-1 in the cyclic switching manner; a vector multiplication circuit, which is used for, by using N groups of multiplication arrays, respectively calculating Wx1xt to WxNxt, or respectively calculating Wh1ht-1 to WhNht-1; an addition circuit, which is used for calculating Wx1xt+Wh1ht-1+b1 to WxNxt+WhNht-1+bN; an activation circuit, which is used for performing an activation operation according to an output of the addition circuit; a state updating circuit, which is used for acquiring ct-1, calculating ct and ht, updating ct-1, and sending ht to the second cache; a bias data cache; a vector cache; and a cell state cache.

Abstract: A data storage method, apparatus, and device, and a readable storage medium. The method includes: after a random access memory is powered on, obtaining target data to be stored in a fixed storage address of the random access memory; determining a target transmission mode from a bit value change transmission mode and a bit value fixed transmission mode, wherein the target transmission mode is different from a historical transmission mode determined after the random access memory is powered on last time; and transmitting the target data from and to the random access memory according to the target transmission mode. The method can prevent data from being stolen after power-down of the target data, and guarantees the data security.

Abstract: A hardware environment-based data quantization method includes: parsing a model file under a current deep learning framework to obtain intermediate computational graph data and weight data that are independent of a hardware environment; performing calculation on image data in an input data set through a process indicated by an intermediate computational graph to obtain feature map data; separately performing uniform quantization on the weight data and the feature map data of each layer according to a preset linear quantization method, and calculating a weight quantization factor and a feature map quantization factor (S103); combining the weight quantization factor and the feature map quantization factor to obtain a quantization parameter that makes hardware use shift instead of division; and finally, writing the quantization parameter and the quantized weight data to a bin file according to a hardware requirement so as to generate quantized file data (S105).

Abstract: The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TR? mutation.

Abstract: An instruction execution method, apparatus and device, and a storage medium are provided. According to the method, normal execution of the instructions without an execution dependency relationship in the batch processing process is ensured, and meanwhile, ordered execution of the instructions with the execution dependency relationship is ensured, and then the correctness of instruction execution results is ensured. In addition, the present application further provides an instruction execution apparatus and device and a storage medium, and the beneficial effects are the same as described above.

Abstract: A battery including a housing assembly, an electrode assembly, and a conductive assembly. The housing assembly includes a first housing fixed on a second housing. The second housing is provided with a cavity and includes a bottom plate. The electrode assembly is disposed in the cavity. The bottom plate contains an elastic portion protruding toward the first housing. The electrode assembly includes a first electrode plate and a second electrode plate stacked together. A surface of the first electrode plate facing back from a center of the electrode assembly contains a first blank foil region uncoated with a first active material and electrically connected to the conductive assembly. A surface of the second electrode plate facing back from the center of the electrode assembly contains a second blank foil region uncoated with a second active material. The elastic portion is electrically connected to the second blank foil region.

Abstract: The present invention provides a method and apparatus for data caching. The method comprises: output matrixes are acquired one by one, a plurality of acquired output matrixes are written alternately into two queue sets of a first cache unit according to a sequence in which the output matrixes are acquired, and the output matrixes stored line by line in a first cache unit are written into a second cache unit one by one, according to the sequence in which the output matrixes are written into the second cache unit, valid data of each output matrix of the second cache unit is determined one by one according to preset parameters, and the valid data of each output matrix is written into a third cache unit, and the valid data of the output matrixes stored in the third cache unit are configured to be sequentially written into a memory according to a sequence in which the valid data are written into the third cache unit.

Abstract: A method, an apparatus, and a device for target detection in consecutive images, and a computer-readable storage medium. A second frame is divided into multiple sub-images, before a target in the second frame in a video sequence is detected through a target-detecting network model. A first frame is searched, according to a preset rule for motion estimation, for a corresponding image block matched with each sub-image. Pixels of a sub-image, of which the matched image block is found in the first frame, are replaced with preset background pixels. Hence, a target repeating in both frames is replaced. Finally, the second frame subject to the replacement is inputted in to the target-detecting network model, to obtain a bounding box of a target object of the second frame and a category of such target object. An algorithm for target detection in consecutive images is optimized.

Abstract: The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TR? mutation.

Abstract: The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TR? mutation.

Abstract: A radio frequency generator, includes an input voltage unit, a smart power unit, a voltage acquisition unit, a power amplifier unit, an output unit, a load unit, a current acquisition unit, a processor unit, a signal transmission and drive unit and an input control unit. The present application combined advantages of the high-frequency electric knife and the radio frequency ablation device, can be used for both cutting and coagulating the target tissue, and the ablation or treatment to the target tissue. This radio frequency generator has high versatility, can be used as standard component to produce and manufacture. Different medical radio frequency manufacturers can produce and manufacture their own products to meet clinical needs of different clients and different departments for example, by changing a small quantity of peripheral circuits or software.

Abstract: A metal-based/diamond laser composite coating preparation method includes: first selecting high-hardness metal powder and diamond powder of a proper grain size and shape; then uniformly mixing the high-hardness metal powder and diamond powder via a ball-milling method; and finally preparing a composite coating on a substrate by synchronously combining laser texturing technology, laser thermal treatment technology and cold spraying technology. The thickness of the composite coating is greater than 1 mm, and the volume content of diamond in the coating is greater than 45%. A metal-based/diamond laser composite coating is also provided.

Abstract: A radio frequency generator, includes an input voltage unit, a smart power unit, a voltage acquisition unit, a power amplifier unit, an output unit, a load unit, a current acquisition unit, a processor unit, a signal transmission and drive unit and an input control unit. The present application combined advantages of the high-frequency electric knife and the radio frequency ablation device, can be used for both cutting and coagulating the target tissue, and the ablation or treatment to the target tissue. This radio frequency generator has high versatility, can be used as standard component to produce and manufacture. Different medical radio frequency manufacturers can produce and manufacture their own products to meet clinical needs of different clients and different departments for example, by changing a small quantity of peripheral circuits or software.

Abstract: A metal-based/diamond laser composite coating preparation method includes: first selecting high-hardness metal powder and diamond powder of a proper grain size and shape; then uniformly mixing the high-hardness metal powder and diamond powder via a ball-milling method; and finally preparing a composite coating on a substrate by synchronously combining laser texturing technology, laser thermal treatment technology and cold spraying technology. The thickness of the composite coating is greater than 1 mm, and the volume content of diamond in the coating is greater than 45%. A metal-based/diamond laser composite coating is also provided.

Abstract: The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TR? mutation.

Abstract: The disclosure describes methods of synthesis of pyridazinone compounds as thyroid hormone analogs and their prodrugs. Preferred methods according to the disclosure allow for large-scale preparation of pyridazinone compounds having high purity. In some embodiments, preferred methods according to the disclosure also allow for the preparation of pyridazinone compounds in better yield than previously used methods for preparing such compounds. Also disclosed are morphic forms of a pyridazinone compound. Further disclosed is a method for treating resistance to thyroid hormone in a subject having at least one TR? mutation.

Abstract: A color printing method includes converting source color data to intermediate color data represented in a device independent color space using a first multidimensional gamut mapping of the first device dependent color space to the device independent color space. The device independent color space has a neutral color component. The method further includes converting the intermediate color data to destination color data represented in a second device dependent color space using a second multidimensional gamut mapping of the device independent color space to the second device dependent color space. The second device dependent color space has three primary color components and a virtual black color component defined by substantially equal tonal values of the three primary color components. The second multidimensional gamut mapping includes a mapping from the neutral color component of the device independent color space to the virtual black color component of the second device dependent color space.