Abstract: A pixel circuit, a display substrate, and a display apparatus are provided. The pixel circuit includes a driving sub circuit, a data writing sub circuit, a first light-emitting control sub circuit, a first reset sub circuit, and a bias sub circuit; the first reset sub circuit is connected to a first node and configured to write a first reset voltage to the first node in response to a first reset control signal; and the bias sub circuit is connected to a second node and configured to write a reference voltage to the second node in response to a bias control signal, thereby turning on the driving sub circuit.

Abstract: Provided are a method and apparatus for controlling an air-conditioning device, a device, a medium, and a program product. The method includes: activating a linkage mode of the air-conditioning device; in the linkage mode, determining, in response to a control instruction for a first adjustment dimension of a plurality of adjustment dimensions of the air-conditioning device and in response to controlling the first adjustment dimension, a target value of the first adjustment dimension; and controlling a second adjustment dimension based on the target value of the first adjustment dimension and an adjustment coefficient for an adjustment from the first adjustment dimension to the second adjustment dimension.

Abstract: A wire take-up and pay-off device, including: a wire take-up and pay-off driver; a rotating shaft, which has a rear end connected with the wire take-up and pay-off driver; a front stop sleeve, fixedly sleeved on a front end of the rotating shaft and rotating synchronously with the rotating shaft; a rear stop sleeve, fixedly sleeved on the rear end of the rotating shaft and rotating synchronously with the rotating shaft; and a wire roller, fixedly sleeved outside of the front stop sleeve and the rear stop sleeve and rotating synchronously with the front stop sleeve and the rear stop sleeve. Further included is a slicing machine having the wire take-up and pay-off device. The wire take-up and pay-off device and the slicing machine have small volumes, thereby facilitating assembly, hoisting and transportation.

Abstract: The disclosure relates to the technical field of autonomous driving, and provides a method for determining a vehicle driving trajectory, a computer device, and a vehicle, to solve the problem of improving the reliability and safety in planning vehicle driving trajectories. The method includes: sequentially simulating, based on an interaction scenario of a vehicle at a current moment by using forward driving of the vehicle as a constraint condition, an interaction scenario of the vehicle at each of a plurality of future moments, to form a scenario tree consisting of the interaction scenarios at the current moment and the future moments; obtaining a scenario value of each interaction intention in the interaction scenario at each moment in the scenario tree; obtaining an optimal interaction intention of the vehicle in the interaction scenario at each moment based on the scenario value; and determining a driving trajectory of the vehicle based on the optimal interaction intention.

Abstract: The disclosure relates to the technical field of autonomous driving, and provides a method for predicting a vehicle trajectory, a control apparatus, and a vehicle, to solve the problem of how to effectively deal with existing highly complex traffic scenario interactions and difficulties in iterative planning and control processes. In the method, scenario interaction results of a traffic agent are obtained based on a static environment perception result and a traffic agent perception result of a vehicle at a current moment, an initial interaction scenario is obtained based on the scenario interaction results, interaction scenario simulation is performed based on the initial interaction scenario and an ego vehicle driving decision to determine an optimal interaction scenario evolution feature of the traffic agent, and an optimal driving trajectory of the vehicle is obtained based on the optimal interaction scenario evolution feature and a state of the vehicle.

Abstract: Provided are an oral solid tablet comprising (S)-7-[4-(1-acryloylpiperidine)]-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide and preparation method therefor. The oral solid tablet has good drug release characteristics, features easy administration, quick and high-efficient release, no particular requirements on equipment, and a simple formulation preparation process, can ensure formulation stability and facilitate transportation and storage, and is suitable for large-scale production.

Abstract: A pixel circuit and a driving method therefor, a display substrate, and a display apparatus. The pixel circuit includes a driving sub circuit, a data writing sub circuit, a first light-emitting control sub circuit, a first reset sub circuit, and a bias sub circuit; the first reset sub circuit is connected to a first node and configured to write a first reset voltage to the first node in response to a first reset control signal; and the bias sub circuit is connected to a second node and configured to write a reference voltage to the second node in response to a bias control signal, thereby turning on the driving sub circuit.

Abstract: Disclosed are a tricyclic derivative and a preparation method therefor and an application thereof. Specifically, disclosed are a compound shown in formula (I) and an optical isomer thereof or a pharmaceutically acceptable salt thereof, and an application of the compound as an Autotaxin inhibitor.

Abstract: An microheater array system includes an integrated microheater array configured to generate a localized heat and having a plurality of pixels. Each pixel includes: an inductor; a stacked oscillator configured to generate a magnetic field at microwave frequencies with tunable intensity and frequency; and an electro-thermal loop. The microheater array system may further include a plurality of magnetic nanoparticles (MNPs).

Abstract: A display substrate, including: a base substrate; a plurality of gate lines and a plurality of data lines that intersect to surround a plurality of pixels; wherein each pixel includes a first thin film transistor, a second thin film transistor and a pixel electrode. A first electrode of the first thin film transistor is electrically connected to a pixel conductive layer of the pixel electrode, a second electrode of the first thin film transistor is electrically connected to a first electrode of the second thin film transistor, and a second electrode of the second thin film transistor is electrically connected to the data line. An orthographic projection of a combination of the second electrode of the first thin film transistor and the first electrode of the second thin film transistor on the base substrate at least partially overlaps with an orthographic projection of the pixel conductive layer on the base substrate.

Abstract: The invention pertains to a measuring system for the conductivity of supercritical geothermal fluid, featuring a reaction control unit with a reaction vessel lined with corundum ceramic and containing a stirrer, a pressure control unit including a booster pump connected to Ar gas and an air compressor, a flow control unit with a flowmeter, and a temperature control unit comprising a heating furnace with thermocouples both inside and outside the reaction chamber. An electrical signal monitoring unit with electrodes fitted through a corundum capillary into the ceramic lining measures current and voltage. The invention also details a method for measuring conductivity, highlighting how water-rock interactions in supercritical geothermal fluids affect conductivity changes.

Abstract: Embodiments provide a pressurizing apparatus, a battery, a battery cell, a processing method, and a production system. The pressurizing apparatus is configured to pressurize a flattened electrode assembly, and includes: a support member configured for placing the electrode assembly; and a pressurizing assembly configured to pressurize the electrode assembly, where the pressurizing assembly and the support member are disposed on two sides of a tab of the electrode assembly. The pressurizing apparatus in the embodiments can reduce the height of a flattened layer of the electrode assembly and the internal space of the battery cell occupied by the flattened layer of the electrode assembly, thus increasing the energy of the battery cell.

Abstract: The present disclosure provides a purification method for 3-amino-5-methylpiperidine with amino protected by Boc. The method includes adding a solvent to the crude product of 3-amino-5-methylpiperidine with amino protected by Boc, heating until it is dissolved to obtain a mixed solution; adding an acid and an amine crystallization auxiliary to the mixed solution, stirring and dispersing to obtain a dispersed solution; cooling the dispersed solution until crystallization, separating and drying same to obtain a salt crystal of 3-amino-5-methylpiperidine with amino protected by Boc. The present disclosure improves the product characters of 3-amino-5-methylpiperidine with amino protected by Boc after salifying and crystallization, thereby improving the yield and purity of the product, at the same time, it simplifies the operation steps of salifying and crystallization of 3-amino-5-methylpiperidine with amino protected by Boc, shortens the operation time, and reduces production costs.

Abstract: Provided in the present disclosure are a nemonoxacin malate active pharmaceutical ingredient with low combination impurities, and a preparation method thereof, specifically, provided in the present disclosure is a method for preparing the nemonoxacin malate active pharmaceutical ingredient, the method includes the following steps: 1) providing a C1-C3 alcohol/water mixed solvent in which nemonoxacin free base (Formula II) and D,L-malic acid are dissolved; and 2) performing cooling crystallization on a mixed solution obtained in the step 1), and then performing solid-liquid separation, washing and drying on a precipitated solid, so as to obtain the nemonoxacin malate active pharmaceutical ingredient.

Abstract: The present disclosure discloses a method for synthesizing quinolones intermediates by a continuous flow reaction. Specifically, according to the method, a microchannel reactor is used, which improves the selectivity and conversion rate of the reaction, and the conversion rate of compound ii is increased to more than 95% and the yield is increased to more than 85%; avoids the use of a solvent such as methanol, and methyl tert-butyl ether, etc., in the intermittent reaction process, which simplifies the post-processing method, shortens the overall operation time from about 24 hours to a few minutes, greatly improving the production efficiency, and realizing the continuity and automation of the whole process; and thus makes the product have high purity and high yield, which is suitable for industrial production.

Abstract: Prokaryotic cells having a metal-phenolic network coating are disclosed, as are compositions including such cells, methods for their use, and methods for producing such cells.

Abstract: Provided in the present disclosure are a nemonoxacin malate active pharmaceutical ingredient with low combination impurities, and a preparation method thereof, specifically, provided in the present disclosure is a method for preparing the nemonoxacin malate active pharmaceutical ingredient, the method includes the following steps: 1) providing a C1-C3 alcohol/water mixed solvent in which nemonoxacin free base (Formula II) and D,L-malic acid are dissolved; and 2) performing cooling crystallization on a mixed solution obtained in the step 1), and then performing solid-liquid separation, washing and drying on a precipitated solid, so as to obtain the nemonoxacin malate active pharmaceutical ingredient.

Abstract: The present invention provides a method for preparing a chiral 4-aryl-?-amino acid derivative. The preparation method comprises hydrogenating an enamine compound having a structure as shown in Formula III in an organic solvent in the presence of a catalyst containing a transition metal and BIBOPs. The preparation method of the present invention uses a small amount of a selected asymmetric catalyst, and has a simple operation, mild reaction conditions, a high yield, a high stereoselectivity, and better industrial application and economic values.

Abstract: Prokaryotic cells having a metal-phenolic network coating are disclosed, as are compositions including such cells, methods for their use, and methods for producing such cells.

Abstract: A method of price text detection by an imaging controller comprises obtaining, by the imaging controller, an image of a shelf supporting labels bearing price text, generating, by the imaging controller, a plurality of text regions containing candidate text elements from the image, assigning, by the imaging controller, a classification to each of the text regions, selected from a price text classification and a non-price text classification. The imaging controller, within each of a subset of the text regions having the price text classification: detects a price text sub-region and generates a price text string by applying character recognition to the price text sub-region. The method further includes presenting, by the imaging controller, the locations of the subset of text regions, in association with the corresponding price text strings.