Abstract: Embodiments of the present disclosure relate to lipid-PEGylated solid support and phosphoramidites derivatives, methods for preparing the same, and their uses in the delivery of oligonucleotide drugs to the cellular targets.

Abstract: A capacitor can include a bottom conductive structure; at least one middle conductive structure, each middle conductive structure having a first conductive pattern and a second conductive pattern surrounding an outer side of the first conductive pattern, where the first conductive pattern and the second conductive pattern of each layer of the middle conductive structure form an interdigitated structure; and a top conductive structure having a third conductive pattern and a fourth conductive pattern arranged at an outer side of the third conductive pattern, where the third conductive pattern and the fourth conductive pattern form an interdigitated structure.

Abstract: The present disclosure relates to a driving assembly having a fixed gear, a fixed rack, a movable intermediate rack, a movable gear, and a transmission rack. The movable intermediate rack cooperates with the fixed gear such that the movable intermediate rack is capable of being driven to reciprocate when the fixed gear rotates clockwise and counterclockwise; the movable rotary shaft is rotatably fixed to the movable intermediate rack, and the movable gear cooperates with the fixed rack such that the movable gear is capable of reciprocatingly translating along an extension direction of the fixed rack when the movable intermediate rack reciprocates, and the movable gear is capable of rotating about the movable rotary shaft; and the transmission rack is capable of driving a member to be driven.

Abstract: The present disclosure relates to antibodies and antibody conjugates, for instance antibody drug conjugates, with binding specificity for receptor tyrosine kinase orphan receptor 1 (ROR1) and its isoforms and homologs, and compositions comprising the antibodies or antibody conjugates, including pharmaceutical compositions. Also provided are methods of producing the antibodies and antibody conjugates and compositions thereof as well as methods of using the antibodies and antibody conjugates and compositions thereof, such as in therapeutic and diagnostic methods.

Abstract: A computing device obtains a to-be-optimized image. The device aligns the to-be-optimized image to obtain a to-be-optimized aligned image. The to-be-optimized aligned image includes a target region having points of objects that are distributed in a standard position. The computing device uses the to-be-optimized aligned image as an inputs to a generation network. The device performs feature extraction on the to-be-optimized aligned image using the generation network, to obtain an optimized image. The generation network is obtained by training a to-be-trained generative adversarial deep neural network model according to a low-quality image pair and a joint loss function. The low-quality image pair includes a target image and a low-quality image corresponding to the target image.

Abstract: The present disclosure discloses a handle assembly for a door having a handle aperture. The handle assembly having a housing, a cover plate and a transmission device. The transmission device can move the cover plate between a closed and open position in response to an electronic signal and, when the cover plate is in the closed position, moving it to the open position by a pushing force from outside. In the handle system, the cover plate is driven by the motor, thus the handle assembly can be electrically connected to the controller, and the cover plate can be automatically opened or closed by means of the controller. The transmission device allows the operator to press the cover plate from outside of the handle assembly to open the cover plate in case of emergency, thus the operator's hand can access the operating cavity for operation, thereby improving the reliability of the handle assembly.

Abstract: Disclosed is a fastening assembly, comprising a fastening element, a compensation element, a holding element, and a limiting element. A limiting portion of the fastening element is provided at a head or between the head and a threaded portion and protrudes outward relative to an outer peripheral surface of the head. The compensation element includes a main body and a receiving hole running therethrough. The main body is provided with a limiting flange to stop the fastening element, and the compensation element can be connected to a first component and move relative to the first component in a longitudinal direction. The holding element at least partially surrounds the head.

Abstract: The present invention relates to an organic-inorganic hybrid short-wave infrared photoelectric detector. A photosensitive layer of the short-wave infrared photoelectric detector comprises a lead sulfide quantum dot thin film with an energy gap?1.24 eV, and a donor-acceptor-blended organic semiconductor structure. Compared with a photoelectric detector with pure lead sulfide quantum dots, the organic-inorganic hybrid photosensitive layer improves the external quantum efficiency of the photoelectric detector in a short-wave infrared region, reduces a dark current density, and improves a response speed, such that the specific detectivity of the photoelectric detector is improved by an order of magnitude. It is worth mentioning that the photoelectric detector can show excellent comprehensive performance under a zero-bias voltage or a relatively low reverse bias voltage. The present invention further relates to an array formed by the photoelectric detector, and a preparation method related thereto.

Abstract: A light-emitting diode device and a manufacturing method therefor, and a display panel and a display apparatus. The light-emitting diode device comprises a quantum dot light-emitting layer, and a hole transport layer located at one side of the quantum dot light-emitting layer, wherein the hole transport layer comprises a perovskite material and an organic hole transport material. The high carrier mobility of a perovskite material can improve the carrier transport performance of a hole transport layer.

Abstract: The present disclosure provides a door handle assembly including a push rod, an ejector rod, a first movable rotating shaft and a second movable rotating shaft. The push rod has a push rod first end and a push rod second end, the ejector rod has an ejector rod first end and an ejector rod second end, the push rod second end is rotatably connected to the ejector rod first end via the first movable rotating shaft, the second movable rotating shaft is rotatably connected to the ejector rod between the ejector rod first end and the ejector rod second end. When the ejector rod abuts against the handle, the push rod applies a first pushing force to the ejector rod, the ejector rod applies a second pushing force to the handle, a component force of the second pushing force in a second direction is greater than the first pushing force.

Abstract: Disclosed are an electromagnet driving mechanism, an electromagnet driving assembly and a dual power automatic transfer switch. The electromagnet driving mechanism includes: a mechanism frame; a stationary core; a movable core, including a moving stroke between a first position away from the stationary core and a second position in contact with the stationary core, the moving stroke including an approaching stroke section; a coil, configured to generate a magnetic attraction force between the stationary core and the movable core upon being energized to drive the movable core to move towards the second position; a reset spring member; and a reset auxiliary assembly, including a push member and a reset auxiliary spring. The reset auxiliary assembly applies a reset auxiliary spring force to the movable core in the approaching stroke section through the push member.

Abstract: The present disclosure provides a device for full-wave field seismic source based on a gas explosion technology and a method for acquiring seismic data. The device includes a cylindrical explosion-proof metal outer barrel, and four sides of the explosion-proof metal outer barrel are fixedly connected to four high-strength steel plates. The device also includes a cylindrical explosion-proof metal gas explosion inner barrel and pipelines for injecting high-pressure air and high-pressure gas into the gas explosion inner barrel. A center of the gas explosion inner barrel is installed with an electronic ignition gun, which is connected to a GPS timing module connected to the electronic ignition gun. The device further includes a controller configured to control a seismic source of a gas explosion full-wave field.

Abstract: A light emitting diode device and a manufacturing method thereof, a display panel, and a display apparatus are provided. The light emitting diode device includes a quantum dot light emitting layer and a hole transport layer on a side of the quantum dot light emitting layer. The hole transport layer includes a perovskite material and an organic hole transport material. The high carrier mobility of the perovskite material can improve the carrier transport performance of the hole transport layer.

Abstract: The present invention provides a viewing angle diffuser film and a display panel, including a base substrate and refractive protrusions. By setting space ratios of adjacent refractive protrusions in a first direction and a second direction, refraction directions of the viewing angle diffuser film can be controlled, and therefore light diffusion effects can be controlled. In the display panel of the present invention, the space ratios of the refractive protrusions in different directions are adjusted according to different usage scenarios to improve display brightness and reduce color shifts.

Abstract: The present disclosure provides a method and a system for acquiring seismic data of a four-component ocean bottom node (OBN). The method is implemented by the system, comprising controlling installations of a plurality of ocean bottom submerged buoys and a plurality of four-component OBN seismic data acquisition instruments and sending positioning signals and timing signals to the plurality of ocean bottom submerged buoys through armored opto-electronic composite cables. The method also includes obtaining real-time and uninterrupted water temperature data, pressure data, density data, and salt saturation data along the armored opto-electronic composite cables from the ocean surface to locations of the plurality of ocean bottom submerged buoys, and calculating real-time and three-dimensional data of waters of a whole measurement work area through interpolation.

Abstract: The present disclosure provides a device for full-wave field seismic source based on a gas explosion technology and a method for acquiring seismic data. The device includes a cylindrical explosion-proof metal outer barrel, and four sides of the explosion-proof metal outer barrel are fixedly connected to four high-strength steel plates. The device also includes a cylindrical explosion-proof metal gas explosion inner barrel and pipelines for injecting high-pressure air and high-pressure gas into the gas explosion inner barrel. A center of the gas explosion inner barrel is installed with an electronic ignition gun, which is connected to a GPS timing module connected to the electronic ignition gun. The device further includes a controller configured to control a seismic source of a gas explosion full-wave field.

Abstract: Disclosed are a viewing angle adjustment film structure, a manufacturing method thereof, and a display device, including a base, an isotropic optical material layer, and a liquid crystal layer stacked in sequence. The isotropic optical material layer is provided with grooves, the liquid crystal layer fills the grooves, and light enters from the liquid crystal layer and then exits through the isotropic optical material layer. Director of liquid crystal molecules in the liquid crystal layer is changed according to an external applied voltage or a change of an electric field, so as to adjust a viewing angle of the light emitted from the isotropic optical material layer.

Abstract: A splicing type light board and a display device are provided with a first LED light board and a second LED light board; a first end of the first LED light board near a first signal input terminal, and a second end away from the first signal input terminal; a first end of the second LED light board near a second signal input terminal, and a second end away from the second signal input terminal; and the first end of the first LED light board connecting the first end of the second LED light board or the second end of the first LED light board connecting the second end of the second LED light board.

Abstract: An organic light-emitting diode (OLED) device includes a substrate, a well structure on the substrate with the well structure having a recess with side walls and a floor, a lower metal layer covering the floor and side-walls of the well, an upper conductive layer on the lower metal layer covering the floor of the well and contacting the lower metal layer, the upper conductive layer having outer edges at about an intersection of the side walls and the floor, a dielectric layer formed of an oxide of the lower metal layer covering the side walls of the well without covering the upper conductive layer, a stack of OLED layers covering at least the floor of the well, the upper conductive layer providing an electrode for the stack of OLED layers, and a light extraction layer (LEL) in the well over the stack of OLED layers and the dielectric layer.

Abstract: The present disclosure provides a method and a system for acquiring seismic data of a four-component ocean bottom node (OBN). The method is implemented by the system, comprising controlling installations of a plurality of ocean bottom submerged buoys and a plurality of four-component OBN seismic data acquisition instruments and sending positioning signals and timing signals to the plurality of ocean bottom submerged buoys through armored opto-electronic composite cables. The method also includes obtaining real-time and uninterrupted water temperature data, pressure data, density data, and salt saturation data along the armored opto-electronic composite cables from the ocean surface to locations of the plurality of ocean bottom submerged buoys, and calculating real-time and three-dimensional data of waters of a whole measurement work area through interpolation.