Abstract: Disclosed is a histone acetyltransferase (HAT) inhibitor. Provided are a compound represented by the general formula I, a pharmaceutically acceptable salt, a stereoisomer, an enantiomer, a diastereoisomer, an atropisomer, a racemate, a polymorph, a solvate or an isotope-labeled compound (including deuterium substitution) thereof, a preparation method therefor, a pharmaceutical composition comprising same and use thereof in the treatment of various HAT-related diseases or conditions.

Abstract: Described are techniques for dynamic rebalancing in storage systems. The techniques including a method comprising calculating an estimated time to storage fullness for respective storage pools in a space balance group, the estimated time to storage fullness based on an allocation speed of the respective storage pools. The method further comprises classifying a first storage pool having a first estimated time to storage fullness below a migration time threshold as a first migration source storage pool. The method further comprises classifying a second storage pool having a second estimated time to storage fullness above the migration time threshold as a first migration target storage pool. The method further comprises rebalancing free space in the space balance group by migrating storage volumes from the first migration source storage pool to the first migration target storage pool.

Abstract: Systems, apparatuses, methods, and computer-readable media are provided for time domain resource allocations in wireless communications systems. Disclosed embodiments include time-domain symbol determination and/or indication using a combination of higher layer and downlink control information signaling for physical downlink shared channel and physical uplink shared channel; time domain resource allocations for mini-slot operations; rules for postponing and dropping for multiple mini-slot transmission; and collision handling of sounding reference signals with semi-statically or semi-persistently configured uplink transmissions. Other embodiments may be described and/or claimed.

Abstract: Disclosed are compounds of Formula A, or a salt thereof: Formula (A), wherein: Het, Q and R1A to R4A are defined herein, which compounds have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula A or their salts, and methods of treating cough, itch, acute pain and neuropathic pain disorders using the same.

Abstract: Provided is a strain CCFM8631 of Lactobacillus reuteri and use thereof. The strain CCFM8631 of Lactobacillus reuteri can significantly increase neurotransmitter 5-hydroxytryptamine level in peripheral blood, recover the hormone levels, for example testosterone and so on in peripheral blood of rat, normalize abnormal abundances of Blautia genus and Turicibacter genus, Oscillospira genus and Bifidobacterium genus in intestinal flora of rat affected by high-fat high-starch diet, show good tolerance to simulated gastrointestinal fluid and quickly colonize in intestinal, significantly improve pathological damages of tissues such as liver, duodenum and so on, and increase triglyceride and total cholesterol levels in serum and oral glucose tolerance of rat with metabolic syndrome caused by high-fat high-starch diet.

Abstract: Technology for a next generation node B (gNB), operable to use phase tracking reference signals (PT-RS) is disclosed. The gNB can identify a modulation and coding 5 scheme (MCS) for the UE for a bandwidth part (BWP) with a subcarrier spacing (SCS). The gNB can select a time density of the PT-RS based on the MCS. The gNB can select a frequency density of the PT-RS based on an allocated bandwidth in the BWP. The gNB can encode the time density and the frequency density, for the PT-RS for transmission to the UE in higher layer signaling.

Abstract: Embodiments of the present disclosure disclose a control method and apparatus of an intelligent device, and a storage medium. The control method includes: determining a state of a target function to acquire target function state information; detecting an operation of a user gazing at a local screen to acquire gazing operation information; and controlling the state of the target function to switch according to the gazing operation information and the target function state information.

Abstract: Embodiments of the present disclosure provide a pixel circuitry and a drive method thereof, an array substrate, and a display panel. The pixel circuitry includes a shift register unit, an inverter, and a pixel driving circuit. The shift register unit is configured to provide a first drive signal under the control of an enable signal, a first clock signal, and a second clock signal. The inverter is configured to invert the first drive signal to generate a second drive signal. The pixel driving circuit is configured to control a light emitting device according to the first drive signal and the second drive signal.

Abstract: An oral irrigator contains: a body, a water tank and a detachable jet tip which are both in connection with the body, a power device and a control device Which are both accommodated in the body. The power device is configured to deliver water from the water tank to the detachable jet tip. The power device includes a first outlet defined thereon and configured to discharge the water, a delivery tube connecting with the first outlet, and a first seal element configured to stop water flowing into the body from the power device so that the water discharges out of the first outlet.

Abstract: The application discloses a method and a device for calculating parameters of a gaze-point calculation model. The method includes: displaying multiple calibration points in sequence on a device screen, and collecting multiple pupil-coordinates data corresponding to each of at least one calibration point of the multiple calibration points; for each calibration point of the at least one calibration point, screening the multiple pupil-coordinates data corresponding to the calibration point, to obtain at least one pupil-coordinates calibration data corresponding to the calibration point; calculating multiple parameters of the gaze-point calculation model according to coordinates data of each calibration point and the at least one pupil-coordinates calibration data corresponding to the calibration point.

Abstract: The present invention discloses a method for relieving vaulted expansion of a cement-stabilized base layer through precut seams. The method firstly establishes an RBFN model according to a large number of observation results of a vaulted expansion amount of the cement-stabilized base layer under different conditions (such as temperature and a stress release structure) in Xinjiang and similar regions; and on such a basis, the vaulted expansion amount of the cement-stabilized base layer to be designed is predicted. When the vaulted expansion amount is greater than a control requirement, the RBFN model is configured to design a reasonable width and a reasonable interval of the precut wide expansion seams to ensure that the vaulted expansion amount of the cement-stabilized base layer is less than a control value. Based on the design of the RBFN model, the present invention provides a corresponding construction method for the precut wide expansion seams.

Abstract: Disclosed are a method and a device for determining the position of a virtual object in a virtual space. The method comprises: detecting whether a predetermined triggering condition is met; when the predetermined triggering condition is met, acquiring at least three sampling points by sampling a movement trajectory of a peripheral device in a reality space; when the movement trajectory forms a loop, determining a reality space plane on which the sampling points exist; converting the reality space plane into a target plane in the virtual space according to a preset transformation relation; and determining the position of a virtual object in the virtual space by setting a designated side of the virtual object on the target plane. By the method and the device according to the present invention, the position of a virtual object in a virtual space may be determined according to the position of a reality object in a reality space, thereby determining the position of the virtual object in the virtual space.

Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.

Abstract: Devices and methods of providing symmetric UL and DL ACK/NACKs is generally described. UL ACK/NACKs of different UEs are multiplexed and received by a UE with a PUSCH. The receiving UE in response transmits the DL ACK/NACK. The ACK/NACK may be transmitted in a localized or distributed manner among subbands that may be adjacent or each may have blocks separated by blocks of a different subband. The ACK and NACK may use independent resources or the NACK may not be transmitted on the single ACK/NACK resource, the lack of an ACK serving as a NACK. The ACK/NACK may be transmitted using a beamforming weight shaped by the received PUSCH/PDSCH. The ACK/NACK symbol may be located in the first symbol, adjacent to the PUSCH/PDSCH, or at the end of a TTI. If adjacent, the UL grant or UL assignment may indicate whether the ACK/NACK resource is used by the PUSCH/PDSCH.

Abstract: There are provided compounds of Formula I, and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, useful for inhibition or modulation of the activity of tyrosine kinases and treatment of disease states or conditions mediated by tyrosine kinases, including cancers.

Abstract: The present disclosure discloses a novel compound, 3,4-dihydroxyphenethyl 3-hydroxybutanoate, a method for preparing the same and use of the same, and in particular, a compound of formula I, use of the compound of formula I, optically pure isomers of the compound, a mixture of enantiomers in any ratio, or pharmaceutically acceptable salts thereof in preparing health food and drug for relieving brain fatigue, improving learning and memory abilities, and ameliorating mania mood related to brain fatigue.

Abstract: The present disclosure provides a smart lock, including: a lock body and an unlocking structure; a Bluetooth communication module configured to receive a lock instruction or an unlock instruction based on Bluetooth communication; and one or more binding tags, each binding tag being associated with a Bluetooth address of the smart lock, wherein the unlocking structure is configured to lock or unlock the smart lock based on the lock instruction or the unlock instruction, or lock or unlock the smart lock based on an operation performed for the one or more binding tags. The present disclosure further provides a system and method for monitoring an object equipped with the smart lock.

Abstract: An electronic device, a list deduplication method and a medium. The method includes: acquiring to-be-processed lists one by one from a database, and analyzing whether the acquired lists have first-type Identifiers (IDs); if the lists have the first-type IDs, looking up customer lists with same first-type IDs as the first-type IDs of the lists in a valid customer database; if the customer lists are not found, looking up customer lists with the same second-type IDs as those of the lists in the valid customer database; if the customer lists are found, checking whether the customer lists have first-type IDs; if the found customer lists have the first-type IDs, refreshing the found customer lists according database, and then comparing the second-type IDs of the lists with the second-type IDs of the customer lists; and if they are matched, deduplicating the lists to be processed.

Abstract: Embodiments of the present disclosure describe methods, apparatuses, storage media, and systems for transmitting uplink control information in new radio (NR) applications. Various embodiments describe how to calculate a number of reserved HARQ-ACK resource elements. Other embodiments may be described and claimed.