Patents by Inventor Ganga Raju Gokaraju

Ganga Raju Gokaraju has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250017999
    Abstract: A synergistic herbal composition includes a combination of from 10% to 90% of a first ingredient comprising an extract of a Punica granatum fruit rind obtained by extraction with a solvent selected from the group consisting of water, ethanol, aqueous ethanol, methanol, aqueous methanol, acetone, aqueous acetone, and ethyl acetate; and from 10% to 90% of a second ingredient comprising an extract of a Theobroma cacao seed obtained by extraction with a solvent selected from the group consisting of water, ethanol, aqueous ethanol, methanol, aqueous methanol, acetone, aqueous acetone, and ethyl acetate. The synergistic herbal composition is effective for increasing testosterone levels, inhibiting aromatase activity, increasing mitochondrial biogenesis, and/or increasing mTOR activation in a patient in need thereof.
    Type: Application
    Filed: September 26, 2024
    Publication date: January 16, 2025
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Kiran BHUPATHIRAJU, Trimurtulu GOLAKOTI, Venkata Kanaka Ranga Raju GOKARAJU, Venkateswarlu SOMEPALLI, Venkata Krishna Raju ALLURI
  • Publication number: 20250000930
    Abstract: Synergistic herbal compositions comprising combination of extracts, fractions or phytochemicals or mixtures thereof derived from Moringa oleifera, Murraya koenigii and Curcuma longa for increasing lean body mass and brown adipose tissue; for accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (WAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products. The invention further provides a method of increasing lean body mass and brown adipose tissue; accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (WAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products in mammals.
    Type: Application
    Filed: August 26, 2024
    Publication date: January 2, 2025
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Trimurtulu GOLAKOTI, Venkateswara Rao CHIRRAVURI, Venkateswarlu SOMEPALLI, Kiran BHUPATHIRAJU
  • Patent number: 12168033
    Abstract: A method for treating a disease condition such as inflammation, arthritis, joint pain, rheumatoid arthritis, osteoarthritis, chronic non-rheumatoid arthritis, and collagen degradation in a patient in need thereof involves administering to the patient an effective amount of a composition: a) a Tamarindus indica seed extract comprising an alcohol or hydroalcohol extract of a Tamarindus indica seed, wherein the alcohol or hydroalcohol extract comprises proanthocyanidins; and b) a Curcuma longa rhizome extract comprising curcuminoids, wherein the Tamarindus indica seed extract and the Curcuma longa rhizome extract are used in a ratio ranging from 1:4 to 4:1.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: December 17, 2024
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju
  • Patent number: 12138288
    Abstract: Synergistic herbal compositions comprising combination of a first ingredient selected from the extract(s), fraction(s), active compound(s) and phytochemicals or mixtures thereof derived from the plant parts of Punica granatum and a second ingredient selected from the extract(s), fraction(s), active compound(s) and phytochemicals or mixtures thereof derived from the plant parts of Theobroma cacao for improving testosterone levels.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: November 12, 2024
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Kiran Bhupathiraju, Trimurtulu Golakoti, Venkata Kanaka Ranga Raju Gokaraju, Venkateswarlu Somepalli, Venkata Krishna Raju Alluri
  • Patent number: 12097236
    Abstract: The invention provides to an enriched Withania somnifera (Ashwagandha) extract composition comprising withanolide glycosides, withanolide aglycones and reduced levels of withaferin-A. The invention also provides to process for the preparation of these compositions and further provides to methods of improving testosterone levels, energy levels, sustained energy, vigor, stamina, and muscle mass and muscle strength using these compositions.
    Type: Grant
    Filed: October 19, 2019
    Date of Patent: September 24, 2024
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Kiran Bhupathiraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Venkateswarlu Somepalli, Venkata Kanaka Ranga Raju Gokaraju
  • Patent number: 12070481
    Abstract: Synergistic herbal compositions comprising combination of extracts, fractions or phytochemicals or mixtures thereof derived from Moringa oleifera, Murraya koenigii and Curcuma longa for increasing lean body mass and brown adipose tissue; for accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products. The invention further provides a method of increasing lean body mass and brown adipose tissue; accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products in mammals.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: August 27, 2024
    Assignees: LAILA NUTRACEUTICALS, P.L. THOMAS-LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Venkateswara Rao Chirravuri, Venkateswarlu Somepalli, Kiran Bhupathiraju
  • Patent number: 11986506
    Abstract: The invention discloses synergistic compositions comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana for inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme or for increasing cGMP levels in a male subject. The invention further discloses a method of inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme, increasing cGMP levels and sexual arousal, treating/alleviating various aspects of male sexual dysfunction or impotence such as erectile dysfunction, loss of libido, or orgasm/ejaculation disorders in a male subject by using a suitable dose of synergistic composition comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: May 21, 2024
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkata Kanaka Ranga Raju Gokaraju, Krishanu Senguptha, Venkata Krishna Raju Alluri
  • Publication number: 20240058409
    Abstract: A gut microbiome may be modulated in a patient in need thereof, by administering a composition comprising 3-O-acetyl-11-keto-b-boswellic acid (AKBA) or an extract of Boswellia serrata comprising from 30% to 90% AKBA to the patient; wherein the composition is administered at a dose sufficient to change the ratio between a first organism in the gut microbiome and a second organism in the gut microbiome, compared to a subject not treated with the composition. Modulation of the gut microbiome with AKBA may be used to treat allergic pulmonary inflammation in the patient. Modulation of the gut microbiome with AKBA may be used to maintain diversity and/or increase a percentage of Bifidobacterium pseudolongum in the gut microbiome of the patient. The composition may further comprise a lyophilized probiotic bacteria. The composition may be administered in combination with a second composition comprising a lyophilized probiotic bacteria.
    Type: Application
    Filed: August 22, 2023
    Publication date: February 22, 2024
    Inventors: Yanjiao Zhou, Seth Flowerman, Ganga Raju Gokaraju, Rama Raju Gokaraju
  • Patent number: 11903991
    Abstract: A method for treating an inflammation, arthritis, or a joint disease in a patient in need thereof, comprising administering to the patient an herbal composition, where the herbal composition includes a therapeutically effective amount of an extract of Terminalia chebula; a therapeutically effective amount of an extract of Curcuma longa; and a therapeutically effective amount of a non-acidic, water-immiscible organic solvent extract of a Boswellia serrata resin.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: February 20, 2024
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakati, Kiran Bhupathiraju, Venkata Krishna Raju Alluri, Krishanu Sengupta
  • Publication number: 20230364173
    Abstract: The present invention discloses synergistic herbal compositions comprising a first ingredient Glycyrrhiza glabra extract containing at least one metal salt of glycyrrhizin selected from zinc salt of glycyrrhizin, potassium salt of glycyrrhizin, zinc/potassium double salt of glycyrrhizin and mixtures thereof; and a second ingredient selected from extract, fraction, phytochemical or mixtures thereof derived from Tinospora cordifolia, Zingiber officinale, Justicia adhatoda, and Ocimum sanctum; process for their preparation, methods of treatment and use of such compositions for improving immunity and improving respiratory health that include allergic airway inflammation, cold and cough.
    Type: Application
    Filed: September 24, 2021
    Publication date: November 16, 2023
    Inventors: Ganga Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Kiran Bhupathiraju, Rama Raju Gokaraju, Venkateswarlu Somepalli, Trimurtulu Golakoti, Krishanu Senguptha, Venkata Krishna Raju Alluri
  • Publication number: 20230346736
    Abstract: The present invention discloses water-soluble 3-O-acetyl-11-keto-?-boswellic acid compositions comprising 3-O-acetyl-11-keto-?-boswellic acid in combination with a metal ion selected from potassium or sodium in the form of respective metal salt or complex or chelate; process for their preparation; methods of prevention, control and/or treatment of at least one disorder selected from muscle soreness, delayed-onset of muscle soreness (DOMS), muscles tenderness, muscle pain, muscle fatigue, muscle sprain, temporary loss of muscle strength and swelling in muscles.
    Type: Application
    Filed: June 23, 2021
    Publication date: November 2, 2023
    Applicant: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Trimurtulu GOLAKOTI, Venkata Kanaka Ranga Raju GOKARAJU, Kiran BHUPATHIRAJU, Venkata Krishna Raju ALLURI, Venkateswarlu SOMEPALLI, Krishanu SENGUPTHA
  • Patent number: 11801277
    Abstract: The invention discloses synergistic herbal composition comprising combination of first ingredient selected from extracts, fractions, phytochemicals and mixtures thereof derived from Theobroma cacao and a second ingredient selected from extracts, fractions, phytochemical and mixtures thereof derived from Citrus aurantifolia for obtaining at least one health benefit selected from preventing, controlling or treating obesity and/or overweight; improving lean body mass, improving the browning of White Adipose Tissue/improving formation of brown adipose tissue, increasing basal metabolic rate/resting energy expenditure, increasing thermogenesis, improving thyroid function, maintaining healthy body weight, increasing satiety/, supporting weight loss, improving fat loss and maintaining a slim body.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: October 31, 2023
    Assignee: Laila Nutraceuticals
    Inventors: Ganga Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkateswarlu Somepalli, Venkata Krishna Raju Alluri, Krishanu Senguptha
  • Publication number: 20230293620
    Abstract: The present invention discloses synergistic herbal compositions comprising a first ingredient Terminalia chebula extract containing metal salt or metal complex or metal chelate of at least one phytochemical in the extract selected from chebulagic acid, chebulinic acid, and gallic acid or mixtures thereof; and a second ingredient selected from extract(s), fraction(s), phytochemical(s) or mixtures thereof derived from Withania somnifera, Tinospora cordifolia and Andrographis paniculata; process for their preparation, methods of treatment and use of such compositions for improving immunity and respiratory health.
    Type: Application
    Filed: August 16, 2021
    Publication date: September 21, 2023
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Kiran Bhupathiraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Venkateswarlu Somepalli, Venkata Krishna Raju Alluri, Krishanu Senguptha
  • Publication number: 20230241152
    Abstract: Synergistic Herbal Compositions For Improving Gut Health” The present invention discloses synergistic herbal compositions comprising at least two ingredients selected from extract(s), fraction(s), phytochemical(s), or mixtures thereof derived each one from a different herb selected from Abelmoschus esculentus, Withania somnifera and Amorphophallus paeoniifolius; improving at least one gut health function selected from gut-brain axis, easing of constipation, bowel movement, improved GI motility, digestion and gut immunity; and reducing gut inflammation. The invention further relates to methods of treatment and the use of the compositions.
    Type: Application
    Filed: May 29, 2021
    Publication date: August 3, 2023
    Inventors: Ganga Raju GOKARAJU, Rama Raju Gokaraju, Kiran BHUPATHIRAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKOTI, Krishanu SENGUPTHA, Venkateswarlu SOMEPALLI, Venkata Krishna Raju ALLURI
  • Patent number: 11707499
    Abstract: The invention discloses odor masking formulations for stench natural compounds, selected from the extracts, fraction and pure phytochemicals that are produced in combination with a natural or synthetic hydrocolloid polymer gum(s). The invention further discloses novel process of producing the odor and taste masking formulations. The invention also discloses taste masking formulations of valerian extracts with no characteristic stench odor & or negligible stench odor in combination with natural hydrocolloid gum such as guar gum, acacia or other polymers. The invention further discloses method of reducing insomnia, anxiety, Attention Deficit Disorder (ADD), Chronic Fatigue Syndrome (CFS) using odor masking formulation of the current invention. Importantly, the said odor masked formulation of the present disclosure helps in improving sleep cycle and helps in efficient functioning of brain.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: July 25, 2023
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Kishore Babu Govada, Venkata Krishna Raju Alluri, Nagendra Babu Vutti, Kiran Bhupathiraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti
  • Patent number: 11684648
    Abstract: Synergistic herbal compositions for Testosterone boosting comprising at least two ingredients selected from the extracts, fractions or pure phytochemicals derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The present invention also describes a synergistic composition comprising at least one testosterone booster ingredient selected from the extracts, fractions or pure phytochemical derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica and at least one aromatase inhibitor ingredient selected from the extracts, fractions or pure phytochemicals derived from Allium cepa, Tamarindus indica and Cinnamomum tamala for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: June 27, 2023
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkata Kanaka Ranga Raju Gokaraju, Krishanu Senguptha, Venkata Krishna Raju Alluri, Venkateswarlu Somepalli
  • Publication number: 20230113013
    Abstract: The invention discloses synergistic herbal compositions comprising the first ingredient selected from the extract(s), fraction(s), phytochemical(s) and mixtures thereof derived from Terminalia chebula in combination with a second ingredient selected from the oil extract(s)/fraction(s) derived from Boswellia serrata gum resin for improving atleast one cognitive functions selected from memory, intelligence, learning, recall information/communication, focus, concentration, reasoning, problem solving, decision making and mental fatigue.
    Type: Application
    Filed: March 3, 2021
    Publication date: April 13, 2023
    Inventors: Ganga Raju Gokaraju, Kiran Bhupathiraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Venkata Kanaka Ranga Gokaraju, Venkateswarlu SOMEPALLI, Venkata Krishna Raju Alluri, Krishanu Senguptha
  • Patent number: 11576941
    Abstract: The invention discloses taste masking formulations for bitter natural compounds, selected from the extracts, fraction and pure phytochemicals produced in combination with a synthetic polymer or a natural polymer. The invention also relates to the novel process of producing the taste masking formulations. The invention also relates to taste masking formulations of Bacopa extracts with no bitter taste or negligible bitter taste in combination with synthetic polymers such as Eudragit or natural polymers such as Shellac.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: February 14, 2023
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Kishore Babu Govada, Venkata Krishna Raju Alluri, Nagendra Babu Vutti, Kiran Bhupathiraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti
  • Patent number: 11426438
    Abstract: Synergistic nutraceutical or pharmaceutical anti-inflammatory compositions include a therapeutically effective combination of: an extract selectively enriched in 3-O-acetyl-11-keto-?-boswellic acid (AKBA) derived from Boswellia serrata; and a Boswellia serrata non-acidic resin extract (BNRE). The compositions can be used to prevent, control and treat inflammation and several inflammatory related diseases including asthma, osteoarthritis, rheumatoid arthritis, and/or endothelial dysfunction. The invention further discloses the amelioration of pro-inflammatory biomarker proteins or molecules, whose expression/production is altered during inflammatory diseases.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: August 30, 2022
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkata Krishna Raju Alluri
  • Publication number: 20220143124
    Abstract: Disclosed herein is Synergistic herbal composition(s) comprising combination of a first ingredient selected from the extract(s), fraction(s), phytochemical(s) and mixtures thereof derived from Murraya koenigii and a second ingredient selected from the extract(s), fraction(s), phytochemical(s) and mixtures thereof derived from Coriandrum sativum or Curcuma amada for improving cartilage growth/repair/regeneration, improving joint mobility, reducing cartilage breakdown, reducing joint pain, reducing stiffness, reducing inflammation and/or treating/alleviating symptoms associated with osteoarthritis. The invention further provides method of improving cartilage growth/repair/regeneration, improving joint mobility, reducing cartilage breakdown, reducing joint pain, reducing stiffness, reducing inflammation and/or treating/alleviating symptoms associated with osteoarthritis in a human or animal.
    Type: Application
    Filed: April 1, 2020
    Publication date: May 12, 2022
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKOTI, Kiran BHUPATHIEAJU, Krishanu SENGUPTHA, Vankata Krishna Raju ALLURI, Venkateswarlu SOMEPALLI