Abstract: Provided herein are anti-CCR8 antibodies or antigen binding fragment thereof, which bind to CCR8, wherein the CCR8 is a human CCR8 and the antibody does not bind human CCR4. The anti-CCR8 antibodies or antigen binding fragment of the disclosure are useful for the treatment of cancer diseases through the elimination of regulatory T cells. Also provided herein are methods of use for the anti-CCR8 antibodies or antigen binding fragment thereof.

Abstract: Aspects of the disclosure include methods and apparatuses for video encoding/decoding. In some examples, an apparatus for video decoding includes processing circuitry. The processing circuitry receives, from a coded video bitstream, coded information associated with a current block in a current picture. The coded information indicates that the current block is coded in a geometric partition mode (GPM), the current block is partitioned into at least a first partition and a second partition in the GPM by a partition edge. The processing circuitry determines that at least the first partition is coded in a subblock motion mode. The first partition includes a plurality of subblocks. The processing circuitry determines a plurality of motion vectors for the plurality of subblocks in the first partition of the current block, and reconstructs the plurality of subblocks in the first partition of the current block according to the plurality of motion vectors respectively.

Abstract: A reference block is determined from a plurality of candidate reference blocks for a current block in a current picture based on template matching (TM) costs of the plurality of candidate reference blocks. The TM costs indicate differences between a template of the current block and respective reference templates of the plurality of candidate reference blocks. Samples of the determined reference block are classified into a plurality of classes of samples. A partitioning pattern of the current block is derived based on the determined reference block from a predetermined plurality of partitioning patterns. The derived partitioning pattern indicates a plurality of partitions of the current block. Each of the plurality of classes of the samples of the determined reference block corresponds to a respective partition of the plurality of partitions of the current block. The current block is reconstructed based on the derived partitioning pattern of the current block.

Abstract: A method for detecting image information includes: acquiring at least one sample of image pair to be processed; calculating a reconstruction loss function of the second feature extraction model based on the first image samples and the first reconstructed image feature information; calculating an adversarial loss function of the third feature extraction model based on the second reconstructed image feature information and the first image samples; optimizing the first model parameters in the first feature extraction model based on the reconstruction and the adversarial loss function to generate the optimized first feature extraction model; inputting the acquired image pair to be processed into the optimized first feature extraction model to generate the difference information. The method reduces the first feature extraction model's dependence on the labeled data and improves the model's recognition efficiency and accuracy by using the samples without the labeled difference information.

Abstract: A packaged cavity structure includes an embedded packaging frame having a first cavity and a first conductive post respectively penetrating an insulation layer in a height direction, a chipset within the first cavity, a first circuit layer on an upper surface of the embedded packaging frame, a first dielectric layer on the first circuit layer, a second circuit layer on the first dielectric layer, a through-hole penetrating the first dielectric layer and the insulation layer, a third circuit layer on a lower surface of the embedded packaging frame, a support post enclosure on the third circuit layer, and a packaging layer formed along the outside of the support post enclosure. A second cavity communicating with the through-hole is formed between the packaging layer and the lower surface of the embedded packaging frame, and the chipset includes a first chip and a second chip provided in a back-to-back stack.

Abstract: Provided herein are anti-EGFRvII antibodies and binding fragments thereof. The anti-EGFRvIII antibodies of the disclosure are useful for the treatment of cancers through, e.g., antibody-dependent cell cytotoxicity (ADCC). Also provided herein are methods of making and using the anti-EGFRvIII antibodies for the treatment of cancer, and polynucleotides that encode the same.

Abstract: A magnetic structure can include: a first magnetic component and a second magnetic component; two magnetic columns configured to form a magnetic flux loop with at least part of the first magnetic component and at least part of the second magnetic component, where at least one of the two magnetic columns is wound with one or more windings; and where the at least part of the first magnetic component is located between the two magnetic columns.

Abstract: A chip high-density interconnection package structure includes a plate having a groove and a glass frame, a first via post penetrating the glass frame, a second via post penetrating the groove, a first line layer and a second line layer on the glass frame and electrically connected via the first via post, a third line layer and a fourth line layer on the groove and electrically connected via the second via post, a chip connection bridge on the third line layer in the groove, and a fifth line layer on the first line layer, and chips on the second line layer and the fourth line layer. The chip connection bridge has a first pad connected to the third line layer, the terminals of the two chips are connected to the fourth line layer and/or the second line layer, and the fifth line layer is connected to the first line layer.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for jointly training an image embedding model and a text embedding model. In one aspect, a method comprises: processing data from a historical query log of a search system to generate a candidate set of training examples, wherein each training example comprises: (i) a search query comprising a sequence of one or more words, (ii) an image, and (iii) selection data characterizing how often users selected the image in response to the image being identified by a search result for the search query; selecting a plurality of training examples from the candidate set of training examples; and using the training data to jointly train the image embedding model and the text embedding model.

Abstract: A method for manufacturing a high-heat-dissipation mixed substrate includes: preparing a mother substrate, the mother substrate including an insulating layer and a temporary carrier plate which are laminated; arranging a plurality of first grooves and a plurality of first cavities on the mother substrate; filling the first groove with a thermally-conductive material to form a first thermally-conductive block, and adhering an embedded device in the first cavity and filling the first cavity with the thermally-conductive material to form a second thermally-conductive block; removing the temporary carrier plate to obtain a semi-finished substrate; manufacturing circuit layers on two opposite side surfaces of the semi-finished substrate to obtain a target mother substrate; and cutting the target mother substrate along region dividing lines to obtain a mixed substrate with a side surface being a thermally-conductive surface.

Abstract: A manufacturing method for an embedded flip chip package substrate includes laminating a first dielectric layer on the first line layer formed on a carrier plate, forming a first window on the first dielectric layer, filling a first copper post in the first window, forming a second window on the first dielectric layer, mounting a flip chip to the second window, sequentially stacking a packaging layer and a second dielectric layer covered with a first metal layer on the first dielectric layer, pressing a packaging layer encapsulating the first copper post and the flip chip and a second dielectric layer, curing the packaging layer, opening a hole through the first metal layer, the second dielectric layer and the packaging layer to form an interlayer conducting blind hole, forming a second line layer on the first metal layer, and removing the carrier plate to obtain a package substrate.

Abstract: An integrated substrate can include: a top structure having a plurality of first pads for mounting electronic devices, where each of the first pads is electrically coupled with a corresponding electronic device, such that each of the first pads has a corresponding potential; a bottom structure having a plurality of second pads for coupling with peripheral circuits; a plurality of intermediate metal layers stacked up/down and located between the top structure and the bottom structure; a first type of penetrating connection structures configured to couple the intermediate metal layers and a part of the first pads, such that the intermediate metal layers have the same potential as the part of the first pads; and a second type of penetrating connection structures configured to couple the intermediate metal layers and the second pads, such that the second pads have the same potential as the part of the first pads.

Abstract: Resource allocation limitations include resource limits and resource guarantees. A consumer is vulnerable to interruption by other consumers if using more resources than guaranteed. Resources are designated and/or assigned consumers based on resource limits and resource guarantees. A constraint programming (CP) solver determines resource limits and resource guarantees that minimize vulnerability and/or vulnerability cost based on resource usage data. A CP data model includes limit elements, guarantee elements, and vulnerability elements. The CP data model further includes guarantee-vulnerability constraints, which relies on exceedance distributions generated from resource usage data for the consumers. The CP data model declaratively expresses combinatorial properties of a problem in terms of constraints. CP is a form of declarative programming.

Abstract: Information about a set of maintenance tasks and time windows includes a cost value per task per time window. Based on the information, a data model generator generates a data model, including task elements; time elements; cost elements; a total cost element; a constraint that requires each task element be assigned a time window from a respective domain, such that each time element is assigned a task count from a respective domain; a constraint that requires each cost element be assigned a cost value associated with a time window assigned (or to be assigned) to a task element corresponding to the cost element; and a constraint that requires the total cost element be assigned a total cost value that is a sum of the cost values assigned (or to be assigned) to the cost elements. Based on the data model, a CP solver determines a proposed maintenance schedule.

Abstract: A method and an apparatus for controlling a robot, an electronic device, and a computer-readable storage medium. The control method includes: acquiring an environmental map obtained by detecting a current environment; detecting the environmental map to acquire at least one right angle corner point in the environmental map; determining a coordinate system in which the right angle corner point is located and using the right angle corner point of which the coordinate system satisfies a preset condition as a target right angle corner point; and controlling the robot to clean the target right angle corner point.

Abstract: The present disclosure relates to a method and an apparatus for processing a data flow of a positioning base station, a device and a computer readable medium. The method includes: extracting, under the condition that a data packet to be processed which is sent by the positioning base station is received, a first identifier carried in the data packet to be processed; screening out a first data packet by using the first identifier, where the first data packet is a data packet to be processed including a distance from the positioning base station to a target position; extracting a second identifier carried in the first data packet, where second identifiers carried in different data packets to be processed sent by the same positioning base station vary; and determining, under the condition that time indicated by the second identifier is target time, the first data packet as a target data packets.

Abstract: Resource allocation limitations include resource limits and resource guarantees. A consumer is vulnerable to interruption by other consumers if using more resources than guaranteed. Resources are designated and/or assigned consumers based on resource limits and resource guarantees. A constraint programming (CP) solver determines resource limits and resource guarantees that minimize vulnerability and/or vulnerability cost based on resource usage data. A CP data model includes limit elements, guarantee elements, and vulnerability elements. The CP data model further includes guarantee-vulnerability constraints, which relies on exceedance distributions generated from resource usage data for the consumers. The CP data model declaratively expresses combinatorial properties of a problem in terms of constraints. CP is a form of declarative programming.

Abstract: Resource allocation limitations include resource limits and resource guarantees. A consumer is vulnerable to interruption by other consumers if using more resources than guaranteed. Resources are designated and/or assigned to consumers based on resource limits and resource guarantees. A constraint programming (CP) solver determines resource limits and resource guarantees that minimize vulnerability and/or vulnerability cost based on resource usage data. A CP data model includes limit elements, guarantee elements, and vulnerability elements. The CP data model further includes guarantee-vulnerability constraints, which relies on exceedance distributions generated from resource usage data for the consumers. The CP data model declaratively expresses combinatorial properties of a problem in terms of constraints. CP is a form of declarative programming.

Abstract: Resource allocation limitations include resource limits and resource guarantees. A consumer is vulnerable to interruption by other consumers if using more resources than guaranteed. Resources are designated and/or assigned to consumers based on resource limits and resource guarantees. A constraint programming (CP) solver determines resource limits and resource guarantees that minimize vulnerability and/or vulnerability cost based on resource usage data. A CP data model includes limit elements, guarantee elements, and vulnerability elements. The CP data model further includes guarantee-vulnerability constraints, which relies on exceedance distributions generated from resource usage data for the consumers. The CP data model declaratively expresses combinatorial properties of a problem in terms of constraints. CP is a form of declarative programming.

Abstract: The invention relates to the technical field of agricultural planting, in particular to a controlled-release bacterial fertilizer for peanuts and a preparation method of the special controlled-release bacterial fertilizer. The special controlled-release bacterial fertilizer is composed of an inner layer and an outer layer; after the outer layer is released completely, the inner-layer network structure gradually absorbs water and preserves moisture, and has good slow release and controlled release properties, thereby achieving the gradual release of the inner layer, high fertilizer utilization rate, exerting the efficacy of the microbial agent and facilitating the large-area promotion.