Patents by Inventor Gareth Griffiths

Gareth Griffiths has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8956878
    Abstract: The present application is directed to a peptides comprising an a-helix forming-amino acid sequence that binds a heat shock protein. Also included is a polypeptide comprising (a) a first peptide portion that comprises an ?-helix-forming amino acid sequence that binds a heat shock protein; and (b) at least one second peptide portion comprising an antigenic amino acid sequence and/or an a-helix-stabilizing amino acid sequence that increases the interaction of the first peptide portion with the heat shock protein. The present application also includes compositions comprising the peptides and/or polypeptides of present application and uses of the peptides and/or polypeptides of the present application for fractionating substances relevant for discovery, research or clinical analysis from a biological sample and as therapeutics.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: February 17, 2015
    Assignees: Atlantic Cancer Research Institute, New England Peptide, Inc.
    Inventors: Steven Gareth Griffiths, Scott Edwin Lewis
  • Publication number: 20140201061
    Abstract: A computerized system for determining whether to provide a loan to a customer who would like to purchase goods from a website of a merchant. The computerized system includes at least one processor, at least one memory, and at least one program stored in at least one of the memories. The at least one program causes the computerized system to respond to a receipt of a notification that the customer is browsing one or more pages of the website by crawling one or more pages of the website to determine the presence or absence of specified features on the pages and providing a decision as to whether or not to authorize a loan to the customer to purchase the goods from the merchant as a function of the presence or absence of the specified features.
    Type: Application
    Filed: March 15, 2013
    Publication date: July 17, 2014
    Inventors: Nikola Sivacki, Daniel Hegarty, Gareth Griffith
  • Publication number: 20130243802
    Abstract: The present application is directed to a peptides comprising an a-helix forming-amino acid sequence that binds a heat shock protein. Also included is a polypeptide comprising (a) a first peptide portion that comprises an ?-helix-forming amino acid sequence that binds a heat shock protein; and (b) at least one second peptide portion comprising an antigenic amino acid sequence and/or an a-helix-stabilizing amino acid sequence that increases the interaction of the first peptide portion with the heat shock protein. The present application also includes compositions comprising the peptides and/or polypeptides of present application and uses of the peptides and/or polypeptides of the present application for fractionating substances relevant for discovery, research or clinical analysis from a biological sample and as therapeutics.
    Type: Application
    Filed: March 21, 2012
    Publication date: September 19, 2013
    Applicant: Atlantic Research Center Institute
    Inventors: Steven Gareth Griffiths, Scott Edwin Lewis
  • Publication number: 20120046462
    Abstract: The invention is directed to a process for the preparation of a chiral cyclic carbamate of formula and/or mirror image, and/or a salt thereof, from the corresponding o-aminobenzyl alcohol and/or salts thereof.
    Type: Application
    Filed: April 9, 2010
    Publication date: February 23, 2012
    Inventors: Aleksander Warm, Miriam Lorenzi, Gareth Griffiths
  • Publication number: 20110236949
    Abstract: Methods are provided for removing or separating the cellular and/or soluble macromolecular component of a biological tissue from the extracellular matrix component of the biological tissue, comprising embedding the biological tissue in an electrically conductive semi-solid or solid supporting medium and applying an electric field to the tissue-medium complex. Additionally, methods are provided for decellularizing a skin fragment.
    Type: Application
    Filed: September 22, 2010
    Publication date: September 29, 2011
    Applicant: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: E. Christopher Orton, Shiori Arai, Carla Maria Ribeiro Lacerda, Leigh Gareth Griffiths
  • Publication number: 20110172419
    Abstract: The invention is directed to a process for the preparation of cyclic carbamates of formula and/or a salt thereof, from the corresponding o-aminobenzyl alcohol and/or a salt thereof.
    Type: Application
    Filed: April 9, 2010
    Publication date: July 14, 2011
    Inventors: Aleksander Warm, Miriam Lorenzi, Gareth Griffiths
  • Patent number: 7803924
    Abstract: The hsp60 gene from a strain of Arthrobacter has been isolated and sequenced. The encoded protein is believed to be highly immunogenic, especially in fish, and also has utility as a non-specific adjuvant, and as an adjuvanting carrier for heterologous antigens.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: September 28, 2010
    Assignee: Novartis AG
    Inventors: Steven Gareth Griffiths, Rachael Jane Ritchie, Nathalie C. Simard
  • Patent number: 7707970
    Abstract: A vaccine based on live Arthrobacter cells is useful in preventing piscirickettsiosis in fish.
    Type: Grant
    Filed: November 9, 2007
    Date of Patent: May 4, 2010
    Assignee: Novartis AG
    Inventors: Kira Salonius, Steven Gareth Griffiths
  • Patent number: 7674892
    Abstract: The hsp70 gene from an Arthrobacter species has been isolated and sequenced. The encoded protein is believed to be highly immunogenic, especially in fish, and also has utility as a non-specific adjuvant, and as an adjuvanting carrier for heterologous antigens.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: March 9, 2010
    Assignee: Novartis AG
    Inventors: Steven Gareth Griffiths, Rachael Jane Ritchie, Nathalie C. Simard
  • Publication number: 20090155313
    Abstract: A vaccine based on live Arthrobacter cells is useful in preventing piscirickettsiosis in fish.
    Type: Application
    Filed: November 9, 2007
    Publication date: June 18, 2009
    Inventors: Kira Salonius, Steven Gareth Griffiths
  • Publication number: 20080287664
    Abstract: The hsp60 gene from a strain of Arthrobacter has been isolated and sequenced. The encoded protein is believed to be highly immunogenic, especially in fish, and also has utility as a non-specific adjuvant, and as an adjuvanting carrier for heterologous antigens.
    Type: Application
    Filed: October 26, 2007
    Publication date: November 20, 2008
    Inventors: Steven Gareth Griffiths, Rachael Jane Ritchie, Nathalie C. Simard
  • Patent number: 7302913
    Abstract: A vaccine based on live Arthrobacter cells is useful in preventing piscirickettsiosis in fish.
    Type: Grant
    Filed: February 14, 2005
    Date of Patent: December 4, 2007
    Assignee: Novartis AG
    Inventors: Kira Salonius, Steven Gareth Griffiths
  • Publication number: 20070079388
    Abstract: A method for maintaining a human hookworm strain is provided by infecting a non-human primate with a non-adapted or non-passaged human hookworm and maintaining the non-human primate. Methods of obtaining human hookworm materials and compositions, such as for use as a vaccine, are also provided, along with a model for maintaining and investigating human hookworm.
    Type: Application
    Filed: November 20, 2006
    Publication date: April 5, 2007
    Inventors: Alan Brown, Doreen Hooi, David Pritchard, Gareth Griffiths, Peter Pearce, Elizabeth Scott
  • Publication number: 20060087618
    Abstract: An ocular display apparatus (10) having image presentation means adapted to display a first image (17) to one eye only of a subject, and a second, different, image (18) to the subject's other eye only, the first and second images being presented to the subject so that they perceive a composite image, wherein at least one of their first or second images includes a moving object.
    Type: Application
    Filed: May 6, 2003
    Publication date: April 27, 2006
    Inventors: Paula Smart, Sue Cobb, Amanda Moody, Richard Eastgate, Gareth Griffiths, Tom Butler, Ian Comaish, Stephen Haworth, Richard Gregson, Isabel Ash, Sarah Brown
  • Patent number: 6913754
    Abstract: The invention provides and immune stimulating agent or vaccine directed to Renibacterium salmoninarum comprising a live non-virulent culture of an Arthrobacter strain based on, derived from or substantially homologous with strain RSxII as deposited as ATCC 55921. The culture may be presented in lyophilized form with a sterile diluent.
    Type: Grant
    Filed: August 5, 2003
    Date of Patent: July 5, 2005
    Assignee: Novartis AG
    Inventors: Steven Gareth Griffiths, Kira Salonius
  • Patent number: 6627203
    Abstract: The invention provides an immune stimulating agent or vaccine directed to Renibacterium salmoninarum comprising a live non-virulent culture of an Arthrobacter strain based on, derived from or substantially homologous with strain RSxII as deposited as ATCC 55921. The culture may be presented in lyophilized form with a sterile diluent.
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: September 30, 2003
    Assignee: Aqua Health (Europe) Limited
    Inventors: Steven Gareth Griffiths, Kira Salonius
  • Patent number: 5698707
    Abstract: A process for the preparation of 2-substituted 5-chloroimidazole-4-carbaldehydes of the general formula: ##STR1## wherein R is hydrogen, an alkyl group, an alkenyl group, a cycloalkyl group, a benzyl group or a phenyl group. The imidazole compounds are important starting products for the preparation of hypotensive pharmaceuticals or herbicides.
    Type: Grant
    Filed: May 10, 1996
    Date of Patent: December 16, 1997
    Assignee: Lonza Ltd.
    Inventors: Gareth Griffiths, Gerhard Stucky
  • Patent number: 5684157
    Abstract: A process for the preparation of 2-substituted 5-chloroimidazole-4-carbaldehydes of the general formula: ##STR1## wherein R is hydrogen, an alkyl group, an alkenyl group, a cycloalkyl group, a benzl group or a phenyl group. The imidazole compounds are important starting products for the preparation of hypotensive pharmaceuticals or herbicides.
    Type: Grant
    Filed: January 14, 1997
    Date of Patent: November 4, 1997
    Assignee: Lonza Ltd.
    Inventors: Gareth Griffiths, Gerhard Stucky
  • Patent number: 5606072
    Abstract: 2-Substituted 5-chlorimidazoles of the general formula: ##STR1## are new intermediate products for the production of antihyperintensive pharmaceutical agents or of herbicidal compounds. A process for the production of these intermediate products as well as a new process for the further reaction of 2-substituted 5-chlorimidazoles of general formula I, wherein R.sub.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: February 25, 1997
    Assignee: Lonza Ltd.
    Inventors: Gareth Griffiths, Ren e Imwinkelried, Jacques Gosteli
  • Patent number: 5536841
    Abstract: A process for preparing 2-substituted 5-chloroimidazole-4-carbaldehydes of the general formula: ##STR1## In the process, a glycine ester hydrohalide is ring-closed with an imidate ester to obtain the intermediate 2-substituted 3,5-dihydroimidazol-4-one. This intermediate is converted with an N,N-substituted formamide acetel into an N,N-substituted aminomethyleneimidazolinone. This latter intermediate is chlorinated with phosphorus oxychloride or phosgene to obtain the final product 2-substituted 5-chlorimidazole-4-carbaldehydes of the general formula I.Also disclosed are N,N-substituted aminomethyleneimidazolinones of the general formula: ##STR2## wherein R is hydrogen or is an alkyl group, an alkenyl group, a cycloalkyl group, an arylalkyl group or an aryl group, and R.sub.5 and R.sub.6 are identical or different and each is an alkyl group or an aryl group, in the form of the E- or Z-isomer.
    Type: Grant
    Filed: June 19, 1995
    Date of Patent: July 16, 1996
    Assignee: Lonza Ltd.
    Inventors: Gareth Griffiths, Rene Imwinkelried, Jacques Gosteli