Patents by Inventor Gareth Hicks

Gareth Hicks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tripartite Modulators of Endosomal G Protein-Coupled Receptors
    Publication number: 20230119819
    Abstract: The present invention relates to tripartite compounds comprising a modulator moiety for endosomal G protein-coupled receptors like neurokinin-1 receptor, a linker and a lipid anchor suitable for anchoring the tripartite compound into a plasma membrane. The present invention also relates to a prodrug and a pharmaceutical composition comprising the tripartite compound and the use of the tripartite compound for the treatment of a disease or disorder mediated by endosomal G protein-coupled receptors signalling like NK1R signalling.
    Type: Application
    Filed: May 6, 2022
    Publication date: April 20, 2023
    Inventors: Nigel W. Bunnett, Christopher John Porter, Derek Cole, Gareth Hicks, Junya Shirai, Gavin Hirst, Luigi Aurelio
  • Tripartite modulators of endosomal G protein-coupled receptors
    Patent number: 11324832
    Abstract: The present invention relates to tripartite compounds comprising a modulator moiety for endosomal G protein-coupled receptors like neurokinin-1 receptor, a linker and a lipid anchor suitable for anchoring the tripartite compound into a plasma membrane. The present invention also relates to a prodrug and a pharmaceutical composition comprising the tripartite compound and the use of the tripartite compound for the treatment of a disease or disorder mediated by endosomal G protein-coupled receptors signalling like NK1R signalling.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: May 10, 2022
    Assignee: Endosome Therapeutics, Inc.
    Inventors: Nigel W. Bunnett, Christopher John Porter, Derek Cole, Gareth Hicks, Junya Shirai, Gavin Hirst, Luigi Aurelio
  • TRIPARTITE MODULATORS OF ENDOSOMAL G PROTEIN-COUPLED RECEPTORS
    Publication number: 20190000981
    Abstract: The present invention relates to tripartite compounds comprising a modulator moiety for endosomal G protein-coupled receptors like neurokinin-1 receptor, a linker and a lipid anchor suitable for anchoring the tripartite compound into a plasma membrane. The present invention also relates to a prodrug and a pharmaceutical composition comprising the tripartite compound and the use of the tripartite compound for the treatment of a disease or disorder mediated by endosomal G protein-coupled receptors signalling like NK1R signalling.
    Type: Application
    Filed: December 21, 2016
    Publication date: January 3, 2019
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Nigel W. Bunnett, Christopher J.H. Porter, Derek Cole, Gareth Hicks, Junya Shirai, Gavin Hirst