Patents by Inventor Gareth William Langley

Gareth William Langley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOINDOLINE DERIVATIVES WHICH BIND TO AN ATP BINDING SITE
    Publication number: 20230061002
    Abstract: The present invention relates to novel probe compounds of formulae I and II defined herein. The present invention also relates to methods of synthesising these novel probe compounds and to their use in assays and screens for determining the binding of a test molecule to the ATP-binding site of a target protein, such as, for example, the Mismatch Repair (MMR) component proteins PMS2 and MLH1, or for determining the location and/or quantity of such target proteins in a biological sample.
    Type: Application
    Filed: January 20, 2021
    Publication date: March 2, 2023
    Inventors: Julian Blagg, Jonathon Richard Anthony Roffey, Paul Colin Michael Winship, Gareth William Langley