Abstract: This invention pertains to mutant Cas9 nucleic acids and proteins for use in CRISPR/Cas endonuclease systems, and their methods of use. In particular, the invention pertains to an isolated mutant Cas9 protein, wherein the isolated mutant Cas9 protein is active in a CRISPR/Cas endonuclease system, wherein the CRISPR/Cas endonuclease system displays reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system. The invention also includes isolated nucleic acids encoding mutant Cas9 proteins, ribonucleoprotein complexes and CRSPR/Cas endonuclease systems having mutant Cas9 proteins that display reduced off-target editing activity and maintained on-target editing activity relative to a wild-type CRISPR/Cas endonuclease system.

Abstract: The Fleetwide Adaptive Rate Limiting Gatekeeper Apparatuses, Processes and Systems (“FARLG”) transforms API call permission request, API call result request datastructure/inputs via FARLG components into API call permission response, API call result response outputs. An API call permission request datastructure associated with an API call of an application structured to identify an API and a set of scopes is obtained. A retry-after interval is determined for each scope in the set of scopes, in which existence of a retry-after interval for a scope indicates that the API previously returned a throttled response for the scope. A wait duration associated with the API call is determined as the maximum retry-after interval across retry-after intervals that exist for the set of scopes. An API call permission response datastructure structured to specify the wait duration is provided.

Abstract: The disclosed systems can regulate access to an online mode for a dynamic transportation matching system. For example, based on a provider efficiency parameter associated with the dynamic transportation matching system, the disclosed systems can prevent a transportation provider device from switching to the online mode within a geographic area. In addition, the disclosed systems can detect a pattern of behavior and, based on a comparison between the pattern of behavior and a behavioral threshold, cause a transportation provider device to switch from the online mode to an offline mode. Further, the disclosed systems can provide a map interface that indicates where a transportation provider device can switch from the offline mode to the online mode. Additionally, the disclosed systems can determine priorities associated with transportation provider devices and, based on the prioritization, selectively allow the transportation provider devices to switch from the offline mode to the online mode.

Abstract: The Fleetwide Adaptive Rate Limiting Gatekeeper Apparatuses, Processes and Systems (“FARLG”) transforms API call permission request, API call result request datastructure/inputs via FARLG components into API call permission response, API call result response outputs. An API call permission request datastructure associated with an API call of an application structured to identify an API and a set of scopes is obtained. A retry-after interval is determined for each scope in the set of scopes, in which existence of a retry-after interval for a scope indicates that the API previously returned a throttled response for the scope. A wait duration associated with the API call is determined as the maximum retry-after interval across retry-after intervals that exist for the set of scopes. An API call permission response datastructure structured to specify the wait duration is provided.

Abstract: Described herein are methods and systems of a drive unit of an electric commercial vehicle. The drive unit may include an electric motor, a transmission, and a differential. The electric motor, transmission, and differential may share lubrication and cooling fluids. Various features for collecting and distribution the lubrication and cooling fluids are also described herein.

Abstract: Described herein are methods and systems of a drive unit of an electric commercial vehicle. The drive unit may include an electric motor, a transmission, and a differential. The electric motor, transmission, and differential may share lubrication and cooling fluids. Various features for collecting and distribution the lubrication and cooling fluids are also described herein.

Abstract: Described herein are methods and systems of a drive unit of an electric commercial vehicle. The drive unit may include an electric motor, a transmission, and a differential. The electric motor, transmission, and differential may share lubrication and cooling fluids. Various features for collecting and distribution the lubrication and cooling fluids are also described herein.

Abstract: The Fleetwide Adaptive Rate Limiting Gatekeeper Apparatuses, Processes and Systems (“FARLG”) transforms API call permission request, API call result request datastructure/inputs via FARLG components into API call permission response, API call result response outputs. An API call permission request datastructure associated with an API call of an application structured to identify an API and a set of scopes is obtained. A retry-after interval is determined for each scope in the set of scopes, in which existence of a retry-after interval for a scope indicates that the API previously returned a throttled response for the scope. A wait duration associated with the API call is determined as the maximum retry-after interval across retry-after intervals that exist for the set of scopes. An API call permission response datastructure structured to specify the wait duration is provided.

Abstract: The invention embodies the systems, processes and methods that collectively administrate and deliver to players a multi-player game in which the players solve a word puzzle and compete against other players for how easily and quickly they solve the puzzle. The game is presented to the players as a matrix of interlocking blank boxes and a list of words or phrases (keys). The keys fit into the matrix in some predetermined fashion. The player must determine the correct orientation of the keys on the puzzle in order to finish the game. Through trial and error the player places the keys into the boxes until the player finds an orientation that fits the puzzle. The player's score is the elapsed time it takes to solve the puzzle adjusted for any clues that are provided. The winner of the game is the player with the lowest score. The game can be used in a variety of advertising and promotional contexts and also can support on-line gaming for prizes.