Patents by Inventor Garrett Hoge

Garrett Hoge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amino acids with affinity for the ?2?-protein
    Patent number: 7388023
    Abstract: Certain ?-amino acids that bind to the alpha-2-delta (?2?) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the ?-amino acids.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: June 17, 2008
    Assignee: Warner-Lambert Company LLC
    Inventors: Peter Garth Blazecka, Joseph Richard Bozelak, Norman Lloyd Colbry, Timothy Thomas Curran, Annise Paige Goodman, Kevin E. Henegar, Garrett Hoge, Paul D. Johnson, Augustine Tobi Osuma, Mark Stephen Plummer, Jacob Bradley Schwarz, Derek Clinton Vrieze, Ji Zhang
  • AMINO ACIDS WITH AFFINITY FOR THE ALPHA-2-DELTA-PROTEIN
    Publication number: 20070129550
    Abstract: Certain ?-amino acids that bind to the alpha-2-delta (?2?) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the ?-amino acids.
    Type: Application
    Filed: December 7, 2006
    Publication date: June 7, 2007
    Applicant: WANER-LAMBERT COMPANY LLC
    Inventors: Peter Blazecka, Joseph Bozelak, Norman Colbry, Timothy Curran, Annise Goodman, Kevin Henegar, Garrett Hoge, Paul Johnson, Augustine Osuma, Mark Plummer, Jacob Schwarz, Derek Vrieze, Ji Zhang
  • Amino acids with affinity for the ?2?-protein
    Patent number: 7179934
    Abstract: Certain ?-amino acids that bind to the alpha-2-delta (?2?) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the ?-amino acids.
    Type: Grant
    Filed: September 24, 2004
    Date of Patent: February 20, 2007
    Assignee: Warner-Lambert Company LLC
    Inventors: Peter Garth Blazecka, Joseph Richard Bozelak, Norman Lloyd Colbry, Timothy Thomas Curran, Annise Paige Goodman, Kevin E. Henegar, Garrett Hoge, Paul D. Johnson, Augustine Tobi Osuma, Mark Stephen Plummer, Jacob Bradley Schwarz, Derek Clinton Vrieze, Ji Zhang
  • C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin
    Publication number: 20050228190
    Abstract: Materials and methods for preparing (S)-(+)-3-(aminomethyl)-5-methyl-hexanoic acid and structurally related compounds via enantioselective hydrogenation of prochiral olefins are disclosed. The methods employ novel chiral catalysts, which include C1-symmetric bisphosphine ligands bound to transition metals.
    Type: Application
    Filed: March 11, 2005
    Publication date: October 13, 2005
    Inventors: Jian Bao, Vladimir Beylin, Derek Greene, Garrett Hoge, William Kissel, Mark Marlatt, Derek Pflum, He-Ping Wu
  • Preparation of P-chirogenic phospholanes and their use in asymmetric synthesis
    Publication number: 20050222464
    Abstract: Materials and methods for preparing P-chirogenic monophospholanes and bisphospholanes are disclosed. The methods employ stereoselective cyclization to generate the phospholane rings followed by pyramidal inversion to access a variety of P-chirogenic phospholanes. When bound to transition metals such as rhodium, the disclosed P-chirogenic phospholanes may be used as catalysts in asymmetric synthesis of valuable pharmaceutical chemical entities, including pregabalin.
    Type: Application
    Filed: March 31, 2005
    Publication date: October 6, 2005
    Inventor: Garrett Hoge
  • Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Publication number: 20050124830
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: January 20, 2005
    Publication date: June 9, 2005
    Inventors: Garrett Hoge, Om Goel
  • Amino acids with affinity for the alpha2delta-protein
    Publication number: 20050101643
    Abstract: Certain ?-amino acids that bind to the alpha-2-delta (?2?) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the ?-amino acids.
    Type: Application
    Filed: September 24, 2004
    Publication date: May 12, 2005
    Inventors: Peter Blazecka, Joseph Bozelak, Norman Colbry, Timothy Curran, Annise Goodman, Kevin Henegar, Garrett Hoge, Paul Johnson, Augustine Osuma, Mark Plummer, Jacob Schwarz, Derek Vrieze, Ji Zhang