Abstract: The present invention relates to a radiation release capsule for controlling radiation exposure and selectively providing electromagnetic pulse therapy, electric field therapy, or treatment drug or gas delivery at a treatment site associated with a treatment environment in accordance with a treatment cycle. The radiation release capsule includes an inner housing that is radiopaque, the inner housing includes an aperture and defines a cavity configured to at least encompass a radiation source. An outer housing is radiopaque. A case is radiation permeable and surrounds the inner housing and outer housing. One of the housing is repositionable blocking all or some of the aperture through which radiation dosage is directionally delivered to the treatment site. A control system operates the radiation release capsule. The capsule can be operated locally by an authorized person to deliver treatment or wirelessly data communicate and be managed remotely in telemedicine applications.