Patents by Inventor Garrett Stewart Hoge

Garrett Stewart Hoge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-C-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Patent number: 7414156
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: August 19, 2008
    Assignee: Warner Lambert Co.
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Preparation of P-chirogenic phospholanes and their use in asymmetric synthesis
    Patent number: 7390931
    Abstract: Materials and methods for preparing P-chirogenic monophospholanes and bisphospholanes are disclosed. The methods employ stereoselective cyclization to generate the phospholane rings followed by pyramidal inversion to access a variety of P-chirogenic phospholanes. When bound to transition metals such as rhodium, the disclosed P-chirogenic phospholanes may be used as catalysts in asymmetric synthesis of valuable pharmaceutical chemical entities, including pregabalin.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: June 24, 2008
    Assignee: Pfizer Inc.
    Inventor: Garrett Stewart Hoge, II
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Patent number: 7230135
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: June 12, 2007
    Assignee: Warner Lambert Company LLC
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Patent number: 6855849
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: September 18, 2002
    Date of Patent: February 15, 2005
    Assignee: Warner-Lambert Company
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Publication number: 20040215027
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: May 10, 2004
    Publication date: October 28, 2004
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Publication number: 20040138487
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 15, 2004
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Patent number: 6750171
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: June 15, 2004
    Assignee: Warner-Lambert Company LLC
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Patent number: 6689915
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: February 10, 2004
    Assignee: Warner-Lambert Company LLC
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Publication number: 20030236433
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: April 18, 2003
    Publication date: December 25, 2003
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Patent number: 6605745
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: August 12, 2003
    Inventors: Garrett Stewart Hoge, II, Om Prakash Goel
  • Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Publication number: 20030073868
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: September 18, 2002
    Publication date: April 17, 2003
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
    Publication number: 20020143214
    Abstract: Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: February 27, 2002
    Publication date: October 3, 2002
    Inventors: Garrett Stewart Hoge, Om Prakash Goel
  • Synthesis of P-chiral bisphospholane ligands and their transition metal complexes for use as asymmetric hydrogenation catalysts
    Publication number: 20020087017
    Abstract: P-chiral bisphospholane ligands and methods for their preparation are described. Use of metal/P-chiral bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.
    Type: Application
    Filed: December 12, 2001
    Publication date: July 4, 2002
    Inventors: Garrett Stewart Hoge, Om Prakash Goel