Patents by Inventor Garrett Whitworth

Garrett Whitworth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective glycosidase inhibitors and uses thereof
    Patent number: 8962664
    Abstract: The invention provides compounds of formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: February 24, 2015
    Assignee: Simon Fraser University
    Inventors: David Vocadlo, Ernest McEachern, Keith Stubbs, Tong-Shuang Li, Garrett Whitworth, Julia Heinonen, Matthew Macauley
  • Selective glycosidase inhibitors and uses thereof
    Patent number: 8334310
    Abstract: The invention provides compounds of formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: December 18, 2012
    Assignee: Simon Fraser University
    Inventors: David Vocadlo, Ernest McEachern, Keith Stubbs, Tong-Shuang Li, Garrett Whitworth, Julia Heinonen, Matthew Macauley
  • SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF
    Publication number: 20120316207
    Abstract: The invention provides compounds of formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds. The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 13, 2012
    Applicant: Simon Fraser University
    Inventors: David Vocadlo, Ernest McEachern, Keith Stubbs, Tong-Shuang Li, Garrett Whitworth, Julia Heinonen, Matthew Macauley
  • SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF
    Publication number: 20100016386
    Abstract: The invention provides compounds of formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds The invention also provides methods of treating diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc
    Type: Application
    Filed: August 31, 2007
    Publication date: January 21, 2010
    Inventors: David Vocadlo, Ernest McFachern, Keith Stubbs, Tong-Shuang Li, Garrett Whitworth, Julia Heinonen, Matthew Macauley
  • Selective Glycosidase Inhibitors, Methods of Making Inhibitors, and Uses Thereof
    Publication number: 20080287375
    Abstract: The invention comprises compounds for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions containing the compounds or prodrugs of the compounds. The invention also comprises animal models and methods of making the animal models for studying diseases and disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc, and treatment of such diseases and disorders. The invention also comprises methods of treating such diseases and disorders. The invention also comprises methods of making the compounds, and methods of making selective glycosidase inhibitors.
    Type: Application
    Filed: March 1, 2006
    Publication date: November 20, 2008
    Applicant: SIMON FRASER UNIVERSITY
    Inventors: David J. Vocadlo, Garrett Whitworth, Matthew S. Macauley