Abstract: The present disclosure relates to methods, compositions, and kits for concentrating and purifying at least one target analyte from a clinical biological sample. In some embodiments, the methods involve one or more aqueous two-phase system (ATPS) compositions and at least one solid phase medium. Some embodiments provide a kit comprising one or more ATPS compositions, a binding buffer; and a solid phase medium. Other embodiments provide methods of treating cancers or infectious diseases in a patient in need thereof.

Abstract: The present disclosure relates to methods, compositions, and kits for isolating target nucleic acids below a target size from a sample comprising nucleic acid components. In some embodiments, the methods involve one or more aqueous two-phase system (ATPS) compositions, at least one solid phase medium, and at least one buffer. Some embodiments provide a kit comprising one or more ATPS compositions, at least one solid phase medium, and at least one buffer. Other embodiments provide methods for diagnosing a disease or condition using the methods described herein.

Abstract: Filter devices. A first chip includes a first base, a first piezoelectric membrane having a first thickness, and a first acoustic Bragg reflector sandwiched between the first piezoelectric membrane and the first base. A first interdigital transducer (IDT) of a first solidly-mounted membrane resonator is formed on a surface of the first piezoelectric membrane. A second chip includes a second base, a second piezoelectric membrane having a second thickness less than the first thickness, and a second acoustic Bragg reflector sandwiched between the second piezoelectric membrane and the second base. A second IDT of a second solidly-mounted membrane resonator is formed on a surface of the second piezoelectric membrane. A circuit card is coupled to the first chip and the second chip, the circuit card including at least one conductor for making an electrical connection between the first IDT and the second IDT.

Abstract: A wagering tool, system or method that allows a player to make skill-based bets on a wide range of sporting events includes the following modules: (a) pricing, which provides the odds on the various competitors, (b) historical event, which stores relevant information pertaining to prior sporting events of the same type that the player is considering placing a bet, (c) forecast, which analyzes prior, similar sporting to determine: (i) similar prior events to the upcoming sporting event, (ii) the shared characteristics of the winners' of these prior events, (iii) the percentage probability that each competitor will win, (d) WIN/Odds, which identifies available “value bets” in the upcoming sporting event, (e) score generation, which rank orders available bets on a “value index” scale, (f) derivative, which identifies bets that could be of special interest; along with a searchable index database, which stores the outputs of the system's various modules and continually updates them; and a user interface that is co

Abstract: A system, method, and computer-readable medium for evaluating structural integrity of a gradient coil disposed in a magnetic resonance imaging system is provided. A sensor obtains a parameter reading of the gradient coil, wherein the parameter reading includes a back electromotive force (back EMF) measurement. The structural integrity of the gradient coil is determined as function of the back EMF measurement.

Abstract: A garage door opener system includes a garage door opener having one or more sensors configured to monitor the status of a garage door as it moves between first and second positions. The garage door opener system may detect one or more anomalies in a profile generated from information from the one or more sensors and alert a user to the presence of those anomalies. The garage door opener system may allow a user to find and contact a service provider to address the one or more anomalies.

Abstract: Filter devices. A first chip includes a first base, a first piezoelectric membrane having a first thickness, and a first acoustic Bragg reflector sandwiched between the first piezoelectric membrane and the first base. A first interdigital transducer (IDT) of a first solidly-mounted membrane resonator is formed on a surface of the first piezoelectric membrane. A second chip includes a second base, a second piezoelectric membrane having a second thickness less than the first thickness, and a second acoustic Bragg reflector sandwiched between the second piezoelectric membrane and the second base. A second IDT of a second solidly-mounted membrane resonator is formed on a surface of the second piezoelectric membrane. A circuit card is coupled to the first chip and the second chip, the circuit card including at least one conductor for making an electrical connection between the first IDT and the second IDT.

Abstract: A method and system is disclosed for validating honesty of a student taking an online test. A camera is used to detect and monitor the test taker's eye movements and eye gaze positions during the taking of the test to ensure the test taker is looking only at the computer display showing the questions and answer choices to the test taker. A microphone is incorporated into, placed on, or in the vicinity of the computer display and the system compares audio received to recorded voice of the test taker to detect another voice. Other voices and eye movement beyond the display screen may be flagged as indicative of dishonest test taking.

Abstract: Filter devices are disclosed. A filter device includes a piezoelectric plate comprising a supported portion, a first diaphragm, and a second diaphragm. The supported portion is attached to a substrate and the first and second diaphragms spans respective cavities in the substrate. A first interdigital transducer (IDT) has interleaved fingers on the first diaphragm. A second interdigital transducer (IDT) has interleaved fingers on the second diaphragm. A first dielectric layer is between the interleaved fingers of the first IDT, and a second dielectric layer is between the interleaved fingers of the second IDT. A thickness of the first dielectric layer is greater than a thickness of the second dielectric layer. The piezoelectric plate and the first and second IDTs are configured such that radio frequency signals applied to first and second IDTs excite primary shear acoustic modes in the respective diaphragms.

Abstract: Filter devices. A first chip includes a first interdigital transducer (IDT) of a first acoustic resonator formed on a surface of a first piezoelectric wafer having a first thickness, interleaved fingers of the first IDT disposed on a portion of the first piezoelectric wafer spanning a first cavity in a first base. A second chip includes a second IDT of a second acoustic resonator formed on a surface of a second piezoelectric wafer having a second thickness less than the first thickness, interleaved fingers of the second IDT disposed on a portion of the second piezoelectric wafer spanning a second cavity in a second base. A circuit card coupled to the first chip and the second chip includes at least one conductor for making an electrical connection between the first IDT and the second IDT.

Abstract: Filter devices. A first chip includes a first interdigital transducer (IDT) of a first acoustic resonator formed on a surface of a first piezoelectric wafer having a first thickness, interleaved fingers of the first IDT disposed on a portion of the first piezoelectric wafer spanning a first cavity in a first base. A second chip includes a second IDT of a second acoustic resonator formed on a surface of a second piezoelectric wafer having a second thickness less than the first thickness, interleaved fingers of the second IDT disposed on a portion of the second piezoelectric wafer spanning a second cavity in a second base. A circuit card coupled to the first chip and the second chip includes at least one conductor for making an electrical connection between the first IDT and the second IDT.

Abstract: A system, method, and computer-readable medium for evaluating structural integrity of a gradient coil disposed in a magnetic resonance imaging system is provided. A sensor obtains a parameter reading of the gradient coil, wherein the parameter reading includes a back electromotive force (back EMF) measurement. The structural integrity of the gradient coil is determined as function of the back EMF measurement.

Abstract: A method and system is disclosed for validating honesty of a student taking an online test. A camera is used to detect and monitor the test taker's eye movements and eye gaze positions during the taking of the test to ensure the test taker is looking only at the computer display showing the questions and answer choices to the test taker. A microphone is incorporated into, placed on, or in the vicinity of the computer display and the system compares audio received to recorded voice of the test taker to detect another voice. Other voices and eye movement beyond the display screen may be flagged as indicative of dishonest test taking.

Abstract: A method and system is disclosed for validating honesty of a student taking an online test. A camera is used to detect and monitor the test taker's eye movements and eye gaze positions during the taking of the test to ensure the test taker is looking only at the computer display showing the questions and answer choices to the test taker. A microphone is incorporated into, placed on, or in the vicinity of the computer display and the system compares audio received to recorded voice of the test taker to detect another voice. Other voices and eye movement beyond the display screen may be flagged as indicative of dishonest test taking.

Abstract: A method and system is disclosed for validating honesty of a student taking an online test. A camera is used to detect and monitor the test taker's eye movements and eye gaze positions during the taking of the test to ensure the test taker is looking only at the computer display showing the questions and answer choices to the test taker. A microphone is incorporated into, placed on, or in the vicinity of the computer display and the system compares audio received to recorded voice of the test taker to detect another voice. Other voices and eye movement beyond the display screen may be flagged as indicative of dishonest test taking.

Abstract: Filter devices. A first chip includes a first base, a first piezoelectric membrane having a first thickness, and a first acoustic Bragg reflector sandwiched between the first piezoelectric membrane and the first base. A first interdigital transducer (IDT) of a first solidly-mounted membrane resonator is formed on a surface of the first piezoelectric membrane. A second chip includes a second base, a second piezoelectric membrane having a second thickness less than the first thickness, and a second acoustic Bragg reflector sandwiched between the second piezoelectric membrane and the second base. A second IDT of a second solidly-mounted membrane resonator is formed on a surface of the second piezoelectric membrane. A circuit card is coupled to the first chip and the second chip, the circuit card including at least one conductor for making an electrical connection between the first IDT and the second IDT.

Abstract: Systems, methods, and software are disclosed herein for supporting an object reshaping feature in software applications. In an implementation, an application receives an input stroke on a canvas in a user interface to the application. The input stroke originates with an instrument-down action on the canvas, terminates with an instrument-up action on the canvas, and comprises a leading component. The application monitors for interactions to occur between the leading component of the input stroke and objects on the canvas during the input stroke. When an interaction occurs between the leading component and an object on the canvas, the application reshapes the object during the input stroke to reflect the interaction.

Abstract: Filter devices. A first chip includes a first interdigital transducer (IDT) of a first acoustic resonator formed on a surface of a first piezoelectric wafer having a first thickness, interleaved fingers of the first IDT disposed on a portion of the first piezoelectric wafer spanning a first cavity in a first base. A second chip includes a second IDT of a second acoustic resonator formed on a surface of a second piezoelectric wafer having a second thickness less than the first thickness, interleaved fingers of the second IDT disposed on a portion of the second piezoelectric wafer spanning a second cavity in a second base. A circuit card coupled to the first chip and the second chip includes at least one conductor for making an electrical connection between the first IDT and the second IDT.

Abstract: Filter devices and methods of fabricating filter devices. A filter device includes a first chip and a second chip. The first chip has a first material stack and contains one or more series resonators of a ladder filter circuit. The second chip has a second material stack and contains one or more shunt resonators of the ladder filter circuit. The first material stack and the second material stack are different.

Abstract: A method and system is disclosed for validating honesty of a student taking an online test. A camera is used to detect and monitor the test taker's eye movements and eye gaze positions during the taking of the test to ensure the test taker is looking only at the computer display showing the questions and answer choices to the test taker. A microphone is incorporated into, placed on, or in the vicinity of the computer display and the system compares audio received to recorded voice of the test taker to detect another voice. Other voices and eye movement beyond the display screen may be flagged as indicative of dishonest test taking.