Patents by Inventor Garry Clark Whitelam

Garry Clark Whitelam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production in yeasts of stable antibody fragments
    Patent number: 5863765
    Abstract: Associative portions of antibody light and heavy chains, especially Fv fragments, are expressed in a transformed organism as a single peptide chain connected by a linking peptide. This is cleaved, possibly while peptide synthesis is incomplete, by an enzyme of the transformed organism which is expressing the single peptide. This ensures production of both chains in equal amounts, but produces them as separate chains which are free to associate and fold.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: January 26, 1999
    Assignee: Quest International BV
    Inventors: Mark John Berry, Paul James Davis, Cornelis Paul Van Der Logt, Garry Clark Whitelam