Patents by Inventor Garry Cole

Garry Cole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL NUCLEIC ACID-GUIDED NUCLEASES
    Publication number: 20240026322
    Abstract: The present disclosure provides novel nucleic acid-guided nucleases and methods of using the nucleases for genome editing. The present disclosure further provides a system for editing a target region in a genome comprising a nucleic acid-guided nuclease, a heterologous guide nucleic acid for complexing with the nucleic acid-guided nuclease, and an editing polynucleotide configured to bind to the target region.
    Type: Application
    Filed: June 16, 2023
    Publication date: January 25, 2024
    Inventors: David Scott JOHNSON, Jan Fredrik SIMONS, Yoong Wearn LIM, Matthew James SPINDLER, Kyle Pierce CARTER, Savreet Kaur SANDHU, Ellen Kathleen WAGNER, Garry Coles, Robert EDGAR
  • Attenuated vaccine useful for immunizations against Coccidioides spp. infections
    Publication number: 20060121061
    Abstract: A Coccidioides spp. fungus that is attenuated by the loss of endosporulation potential of the fungus wherein said fungus does not replicate when transformed into the parasitic phase.
    Type: Application
    Filed: December 2, 2005
    Publication date: June 8, 2006
    Applicant: MEDICAL UNIVERSITY OF OHIO
    Inventors: Garry Cole, Xia Chen, Kalpathi Seshan, Chiung-Yu Hung, Jianmin Xue, Jieh-Juen Yu
  • Attenuated vaccine useful for immunizations against Coccidioides spp. infections
    Publication number: 20050260233
    Abstract: The present invention provides compositions of attenuated fungal mutants and polynucleotide sequences used to transform fungal strains by gene deletions or gene replacements, which are useful for generating an immunological response in human and animals and in therapeutic applications of infections due to pathogenic Coccidioides spp. fungi, such as C. immitis or C. posadasii.
    Type: Application
    Filed: April 7, 2005
    Publication date: November 24, 2005
    Applicant: MEDICAL COLLEGE OF OHIO
    Inventors: Garry Cole, Charles Okeke, Chiung-Yu Hung