Abstract: Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.

Abstract: Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.

Abstract: A risk/reliability assessment tool for ultra-deepwater well control equipment used for offshore drilling operations is disclosed. Embodiments take into consideration all of the processes required for competent risk/reliability assessment for loss mitigation. In an illustrative embodiment, the system provides a simulation tool which evaluates equipment components and simulates the various failure modes for each component and the effect on the other components in the equipment being evaluated. An automated reporting tool quickly identifies components, failure modes for components, and troubleshooting information.

Abstract: A risk/reliability assessment tool for ultra-deepwater well control equipment used for offshore drilling operations is disclosed. Embodiments take into consideration all of the processes required for competent risk/reliability assessment for loss mitigation. In an exemplary embodiment, the system provides a simulation tool which evaluates equipment components and simulates the various failure modes for each component and the effect on the other components in the equipment being evaluated.

Abstract: A window frame assembly to secure a glass pane within a window opening in a door slab. The assembly preferably includes two identical frame halves carrying bosses on which modular clip members are secure. The clip members each carry a male post member and a female socket member. Each clip member on a half frame engages a corresponding clip member on the other half frame with their female and male socket members engaging the outer surface of the clip member carrying a key member complementary to the keying member.

Abstract: A window frame assembly to secure a glass pane within a window opening in a door slab. The assembly preferably includes two identical frame halves carrying bosses on which modular clip members are secure. The clip members each carry a male post member and a female socket member. Each clip member on a half frame engages a corresponding clip member on the other half frame with their female and male socket members engaging the outer surface of the clip member carrying a key member complementary to the keying member.

Abstract: The Flow Controlled Y Connector is a device used to control the flow of a mixture of air, water, and debris that occurs as a result of a vacuum that is created by carpet cleaning equipment. This device is effectively a piping and valve system that opens and closes based on the flow rate of the matter passing through the system.

Abstract: The mixing valve controller is a device that is used to control the position of a mixing valve used to regulate the temperature of flowing water. The device uses an embedded system programmed to control a stepper motor and read inputs from a thermocouple, position sensor, and graphical user interface.

Abstract: A magnetic flux shield extending substantially the entire width of a magnetic disk drive spindle motor magnet is mounted between the magnet and the disk drive's base frame and rotates with the magnet. The flux shield is formed of a magnetic material to capture any stray magnetic flux from the motor magnet that may produce power draining eddy currents in the base frame.

Abstract: The present invention includes apparatus and methods to suppress transients that would otherwise have an effect on a power supply. The present invention accomplishes this by providing a power supply transient suppressor between the power supply and an inductive load, such as a spindle motor of a disc drive. The power supply transient suppressor is turned off at certain desired times so that transients caused by the inductive load do not affect the power supply. One apparatus to accomplish this suppression is to use an isolation transistor and a blocking diode. The blocking diode can be a discrete device or can be inherent in the isolation transistor. The isolation transistor is turned on and off so that undesired transients are not passed to the power supply. For example, during spin up of the spindle motor, the isolation transistor can be turned on and off to block the transients from passing to the power supply.

Abstract: A motor comprises a shaft supported from a base frame and supporting a hub and one or more on the outer diameter thereof. A stator is supported from the shaft, and comprises a plurality of laminations supporting coils which are sequentially energized to cause rotation of a hub which overlies the stator and supports a magnet and back iron radially adjacent these stator coils. A shield is provided extending substantially the entire width of the magnet and intervening between the magnet and the base frame and rotating with the magnet. The flux shield is formed of a magnetic material to capture any stray magnetic flux from the motor magnet.

Abstract: A disc drive includes a base, a spindle rotatably attached to the base, and at least one disc attached to the spindle. A cover is attached to the base. The cover and the base form a disc enclosure for the spindle and the disc or discs. A pump mechanism is located within the disc enclosure. The pump mechanism reduces the pressure within the disc enclosure. A valve is located in one of the cover and the base and allows a gas or fluid to move out of the disc enclosure.

Abstract: A motor control circuit controls a motor in a disc drive. The motor control circuit includes a voltage controlled oscillator (VCO) providing a commutation timing signal. A commutation circuit is operably coupled to the VCO and provides commutation signals to the motor based on the commutation timing signal. A phase locked feedback circuit is operably coupled to the commutation circuit and provides a feedback signal to the VCO based on a sensed commutation phase to control a frequency of the commutation timing signal. A modulator is operably coupled to the phase locked feedback circuit and modulates the feedback signal. A method is also provided in which the commutation timing signal is modulated so as to spread a frequency spectrum of the commutation signals.

Abstract: An improved animal carcass spreader which comprises a crossbar with spreader arms mounted thereon. The spreader arms are curvilinear members having end portions with spikes mounted thereon for spreading the ribs of an animal. One of the spreader arms is fixedly mounted at the distal end of the crossbar, while the opposing spreader arm is slidably mounted. The slidable spreader arm is provided with a handle and a ratchet lever. The ratchet lever permits travel of the slidable spreader arm only in a direction away from the fixed spreader arm unless said ratchet lever is manually disengaged by squeezing the ratchet lever towards the handle and a raised stopper is provided to prevent the ratchet lever from sliding completely off the crossbar.

Abstract: A four component six lens element Gauss type objective having an aperture ratio of at least 1:2.4 and a field angle of greater than 40.degree. , comprising in the direction of light travel: a first single component positive meniscus concave toward the diaphragm; a second and third cemented doublet meniscus component concave toward the diaphragm, each of the doublet components having planar bond surfaces and a low positive or negative power of refraction; a diaphragm located between said second and third component; and a fourth single component having positive power of refraction with the weaker surface facing the diaphragm; wherein at least two pairs of spherical lens surfaces which are arranged symmetrically with respect to the diaphragm have identical radii of curvature; wherein the ratio of the dispersion values of the first and sixth lens, of the second and fifth lens, and of the third and fourth lens, respectively, in the direction of light travel, are essentially as follows:0.58 .ltoreq. .nu..sub.1 : .