Patents by Inventor Garry Pairaudeau

Garry Pairaudeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cathepsin cysteine protease inhibitors and their use
    Publication number: 20060111364
    Abstract: The present invention relates to compounds and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition this invention also discloses processes for the preparation of such inhibitors.
    Type: Application
    Filed: December 11, 2003
    Publication date: May 25, 2006
    Inventors: Judith McInally, Garry Pairaudeau, Anil Patel, Stephen Thom
  • Cyclopentan-2-ol-1-yl-[1,2,3]triazolo[4,5-D]pyrimidine compounds
    Patent number: 7034032
    Abstract: The invention provides novel 1,2,3-triazolo[4,5-d]pyrimidine compounds, such as those represented by formula (I): their use as medicaments, particularly in platelet aggregation disorders, compositions containing them and processes for their preparation.
    Type: Grant
    Filed: November 7, 2001
    Date of Patent: April 25, 2006
    Assignee: AstraZeneca AB
    Inventors: Roger Brown, Simon Guile, Garry Pairaudeau, Brian Springthorpe
  • Novel compounds
    Publication number: 20050245522
    Abstract: The present invention relates to compounds and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition this invention also discloses processes for the preparation of such inhibitors.
    Type: Application
    Filed: June 23, 2003
    Publication date: November 3, 2005
    Inventors: Andrew Bailey, Garry Pairaudeau, Anil Patel, Stephen Thom
  • New use of pyrimidine - or triazine - 2 carbonitiles for treating diseases associated with cysteine prostease activity and novel pyrimidine-2-carbonitile derivatives
    Publication number: 20050222152
    Abstract: The present invention therefore provides use of a compound of formula (I) and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition, this invention also discloses processes for the preparation of such inhibitors.
    Type: Application
    Filed: June 23, 2003
    Publication date: October 6, 2005
    Inventors: Andrew Bailey, Garry Pairaudeau, Anil Patel, Stephen Thom
  • Novel purine-or pyrrolol[2,3-d]pyrimidine-2-carbonitiles for treating diseases associated with cysteine protease activity
    Publication number: 20050203107
    Abstract: The present invention therefore provides a compound of formula (I) and compositions for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases S, K, F, L and B. Of particular interest are diseases associated with Cathepsin S. In addition this invention also discloses processes for the preparation of such inhibitors.
    Type: Application
    Filed: June 23, 2003
    Publication date: September 15, 2005
    Inventors: Andrew Bailey, Garry Pairaudeau, Anil Patel, Stephen Thom
  • P2X7 receptor antagonists for use in the treatment of inflammatory, immune or cardiovascular disease
    Patent number: 6812226
    Abstract: The invention provides piperidine compounds of general formula (I) in which A, B, X, Y, Z, R, R1 and R2 are as defined in the specification, their use as medicaments, compositions containing them and processes for their for their preparation.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: November 2, 2004
    Assignee: AstraZeneca AB
    Inventors: Andrew Baxter, Nicholas Kindon, Garry Pairaudeau, Bryan Roberts, Stephen Thom
  • Novel compounds
    Publication number: 20040023988
    Abstract: The invention provides novel 1,2,3-triazolo[4,5-d]pyrimidine compounds, their use as medicaments, compositions containing them and processes for their preparation.
    Type: Application
    Filed: April 24, 2003
    Publication date: February 5, 2004
    Inventors: Roger Brown, Simon Guile, Garry Pairaudeau, Brian Springthorpe
  • P2x7 receptor antagonists for use in the treatment of inflammatory, immune or cardiovascular diseases
    Publication number: 20030040513
    Abstract: The invention provides piperidine compounds of general formula (I) in which A, B, X, Y, Z, R, R1 and R2 are as defined in the specification, their use as medicaments, compositions containing them and processes for their for their preparation.
    Type: Application
    Filed: June 13, 2002
    Publication date: February 27, 2003
    Inventors: Andrew Baxter, Nicholas Kindon, Garry Pairaudeau, Bryan Roberts, Stephen Thom
  • Triazolo(4,5-d)pyrimidine compounds
    Patent number: 6369064
    Abstract: Triazolo[4,5-d]pyrimidine compounds are provided of the formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification. Compositions containing the compounds are also provided, together with processes for their preparation and methods of use in the treatment of diseases, including myocardial infarction and unstable angina.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: April 9, 2002
    Assignee: AstraZeneca AB
    Inventors: Roger Brown, Garry Pairaudeau, Brian Springthorpe, Stephen Thom, Paul Willis
  • Compounds
    Patent number: 6166022
    Abstract: Triazolo[4,5-d]pyrimidine compounds of the formula ##STR1## where R.sup.1 through R.sup.4 and X are as defined in the specification are provided, together with compositions containing them, a process for their preparation and methods of use. The compounds are useful in the treatment of platelet aggregation disorders and angina.
    Type: Grant
    Filed: September 30, 1999
    Date of Patent: December 26, 2000
    Assignee: AstraZeneca UK Limited
    Inventors: Roger Brown, Garry Pairaudeau
  • Benzothiazolone derivatives
    Patent number: 5846989
    Abstract: A compound of formula I, including optical isomers thereof, ##STR1## wherein X represents --SO.sub.2 NH-- or --NHSO.sub.2 --,p, q and r independently represent 2 or 3,Y represents thienyl optionally substituted by alkyl or halogen, or phenylthio- or phenyl optionally substituted by alkyl or halogen, andeach R independently represents H or alkyl,and pharmaceutically acceptable salts, esters and amides thereof.
    Type: Grant
    Filed: February 7, 1997
    Date of Patent: December 8, 1998
    Assignee: Astra Pharmaceuticals Limited
    Inventors: Roger Victor Bonnert, Roger Charles Brown, Peter Alan Cage, Francis Ince, Garry Pairaudeau