Patents by Inventor Garth Whiteside

Garth Whiteside has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treatment and dosage forms thereof
    Patent number: 12201629
    Abstract: The invention provides an oral dosage form comprising (i) an amount of oxycodone and (ii) an amount of buprenorphine, wherein the weight ratio of the amount of buprenorphine to the amount of oxycodone is greater than 1:40 calculated with the amount of buprenorphine in the dosage form expressed as the equimolar amount of buprenorphine base (Mw=467.64 g/mol) in mg, and the amount of oxycodone in the dosage form expressed as the equimolar amount of oxycodone hydrochloride (Mw=351.82 g/mol) in mg. The invention also provides combinations of an opioid agonist and buprenorphine for use to treat pain, wherein the combination achieves a reduction of adverse pharmacodynamic responses (such as, respiratory depression), compared with a corresponding stand-alone opioid therapy. The invention also includes methods of treatment and dosage forms thereof comprising such combinations.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: January 21, 2025
    Assignee: Purdue Pharma L.P.
    Inventors: Alessandra Cipriano, Salvatore Colucci, Stephen Harris, Michele Hummel, Donald Kyle, Garth Whiteside
  • Sleep disorder treatment and prevention
    Patent number: 12171762
    Abstract: The disclosure relates to methods for treating or preventing an Insomnia Disorder by administering to a human in need thereof a compound of formula (I), or a compound of formula (IA), (IB), or (IC), or a solvate thereof, in a daily dose of from about 0.5 mg to about 6.0 mg. In certain embodiments, such compounds effectively treat or prevent an Insomnia Disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Grant
    Filed: January 10, 2023
    Date of Patent: December 24, 2024
    Assignee: Purdue Pharma L.P.
    Inventors: Stephen C. Harris, Ram P. Kapil, Donald J. Kyle, Garth Whiteside
  • Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
    Publication number: 20240350479
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: February 8, 2024
    Publication date: October 24, 2024
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Treatment and prevention of sleep disorders
    Patent number: 11738023
    Abstract: The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: August 29, 2023
    Assignee: Purdue Pharma L.P.
    Inventors: Stephen C. Harris, Ram P. Kapil, Donald J. Kyle, Garth Whiteside
  • Sleep disorder treatment and prevention
    Patent number: 11576913
    Abstract: The disclosure relates to methods for treating or preventing an Insomnia Disorder by administering to a human in need thereof a compound of formula (I), or a compound of formula (IA), (IB), or (IC), or a solvate thereof, in a daily dose of from about 0.5 mg to about 6.0 mg. In certain embodiments, such compounds effectively treat or prevent an Insomnia Disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: February 14, 2023
    Assignee: Purdue Pharma L.P.
    Inventors: Stephen C. Harris, Ram P. Kapil, Donald J. Kyle, Garth Whiteside
  • Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
    Publication number: 20210196706
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: March 16, 2021
    Publication date: July 1, 2021
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Treatment and prevention of sleep disorders
    Patent number: 10974081
    Abstract: The disclosure relates to methods for treating or preventing a sleep disorder by administering a compound of formula (1)(1), or a compound of formula (1A), (1B), (1C), (1D), (1E), or (1F) to an animal in need of such treatment. In certain embodiments, such compounds effectively treat or prevent a sleep disorder in the animal, while producing reduced side effects compared to previously available compounds.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: April 13, 2021
    Assignee: Purdue Pharma L.P.
    Inventors: Stephen C. Harris, Ram P. Kapil, Donald J. Kyle, Garth Whiteside
  • SYSTEMS AND METHODS FOR ATTENUATING OPIOID-INDUCED EUPHORIA
    Publication number: 20200276187
    Abstract: Disclosed in certain embodiments is a method of attenuating or preventing opioid-induced euphoria comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: March 24, 2020
    Publication date: September 3, 2020
    Applicant: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
    Publication number: 20200155542
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: July 31, 2019
    Publication date: May 21, 2020
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and methods for treating an opioid-induced adverse pharmacodynamic response
    Patent number: 10398690
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: September 3, 2019
    Assignee: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and methods for treating an opioid-induced adverse pharmacodynamic response
    Patent number: 10226457
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: March 12, 2019
    Assignee: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Methods and compositions for decreasing gastric emptying
    Patent number: 10143696
    Abstract: Disclosed in certain embodiments is a method of decreasing gastric emptying comprising administering to a subject an effective amount of a sodium-channel blocker to decrease gastric emptying.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: December 4, 2018
    Assignee: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside, Nathan Lautermilch
  • Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
    Publication number: 20180193331
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: December 8, 2017
    Publication date: July 12, 2018
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
    Publication number: 20180104237
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Application
    Filed: December 18, 2017
    Publication date: April 19, 2018
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and methods for treating an opioid-induced adverse pharmacodynamic response
    Patent number: 9931337
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: April 3, 2018
    Assignee: Purdue Pharma L.P.
    Inventors: Michelle Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and methods for treating an opioid-induced adverse pharmacodynamic response
    Patent number: 9884059
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: February 6, 2018
    Assignee: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and methods for treating an opioid-induced adverse pharmacodynamic response
    Patent number: 9872856
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: January 23, 2018
    Assignee: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and methods for treating an opioid-induced adverse pharmacodynamic response
    Patent number: 9867817
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: January 16, 2018
    Assignee: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and methods for treating an opioid-induced adverse pharmacodynamic response
    Patent number: 9855262
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: January 2, 2018
    Assignee: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside
  • Systems and methods for treating an opioid-induced adverse pharmacodynamic response
    Patent number: 9849124
    Abstract: Disclosed in certain embodiments is a method of treating or preventing an opioid induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: December 26, 2017
    Assignee: Purdue Pharma L.P.
    Inventors: Michele Hummel, Donald J. Kyle, Garth Whiteside