Patents by Inventor Gary A. Eiceman

Gary A. Eiceman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210088474
    Abstract: An ion-mobility spectrometer system includes a housing with an upstream end, a downstream end, and a drift region defined along a longitudinal axis through the housing between the upstream and downstream ends. A first ionizer is operatively connected the housing to supply ions at the upstream end. A second ionizer is operatively connected to the housing to supply ions at the upstream end, wherein the first and second ionizers are both situated upstream of the drift zone relative to an ion flow path through the drift zone. An electric field generator is operatively connected to the housing to drive ions through the drift zone in a direction from the upstream end toward the downstream end. The second ionizer is a radioactive ionizer mounted to the housing at the upstream end positioned to direct irradiated ions into the housing.
    Type: Application
    Filed: September 21, 2020
    Publication date: March 25, 2021
    Applicant: Hamilton Sundstrand Corporation
    Inventors: Benjamin D. Gardner, Gary A. Eiceman, Hsien-Chi W. Niu, Peter Fowler
  • Patent number: 10930485
    Abstract: An ion mobility spectrometer for analyzing a vapor sample including a multi-ring ion source for receiving a vapor sample, wherein the multi-ring ion source includes a series of rings, wherein each ring of the multi-ring ion source includes an ionizing layer on an inner surface thereof, for charging at least a portion of the vapor sample and creating an ionized vapor sample.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: February 23, 2021
    Assignee: Hamilton Sundstrand Corporation
    Inventors: Benjamin D. Gardner, Gary A. Eiceman, Hermann Wollnik
  • Publication number: 20200312646
    Abstract: An ion mobility spectrometer for analyzing a vapor sample including a multi-ring ion source for receiving a vapor sample, wherein the multi-ring ion source includes a series of rings, wherein each ring of the multi-ring ion source includes an ionizing layer on an inner surface thereof, for charging at least a portion of the vapor sample and creating an ionized vapor sample.
    Type: Application
    Filed: March 25, 2019
    Publication date: October 1, 2020
    Inventors: Benjamin D. Gardner, Gary A. Eiceman, Hermann Wollnik
  • Publication number: 20200286723
    Abstract: An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
    Type: Application
    Filed: April 7, 2020
    Publication date: September 10, 2020
    Inventors: Gary A. Eiceman, Stephen J. Davila, Stefan R. Lukow, Hartwig Schmidt
  • Patent number: 10651024
    Abstract: An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: May 12, 2020
    Assignee: Rapiscan Systems, Inc.
    Inventors: Gary A. Eiceman, Stephen J. Davila, Stefan R. Lukow, Hartwig Schmidt
  • Publication number: 20200027711
    Abstract: An apparatus for separating and analyzing ions includes a detector, a planar ion drift tube coupled to the detector and having a width, and a planar ion source. The planar ion source is coupled to the ion drift tube on an end of the ion drift tube opposite the detector and has a span greater than or equal to the width of the ion drift tube to ionize an analyte gas and fragment the analyte gas ions prior to admittance to the ion drift tube. Chemical detectors and methods of chemical detection are also described.
    Type: Application
    Filed: July 23, 2018
    Publication date: January 23, 2020
    Inventors: Gary Eiceman, Benjamin D. Gardner, Hsien-Chi W. Niu
  • Publication number: 20200027713
    Abstract: An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
    Type: Application
    Filed: May 17, 2019
    Publication date: January 23, 2020
    Inventors: Gary A. Eiceman, Stephen J. Davila, Stefan R. Lukow, Hartwig Schmidt
  • Publication number: 20190204274
    Abstract: A system for multi-stage differential mobility spectrometer (multi-stage DMS) and the method of operating and using the same are described. Ions produced in an ionization source are introduced into the separation region of multi-stage DMS, which includes at least two DMS stages. Each DMS stage is configured to generate separation and compensation fields to characterize, separate, or select ion species. The separation region further includes ion alteration stages which are placed between various adjacent stages of multi-stage DMS. Alteration of ions can be both chemical and physical. Ions which are separated, altered, and selectively passed by all DMS stages of multi-stage DMS are then measured or further characterized by the Faraday plate detectors or a mass spectrometer.
    Type: Application
    Filed: December 17, 2018
    Publication date: July 4, 2019
    Inventors: Gary A. Eiceman, Marlen R. Menlyadiev, Hartwig Schmidt, Stefan R. Lukow, Peter Fowler, Gyoungil Lee
  • Publication number: 20190139752
    Abstract: An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
    Type: Application
    Filed: July 10, 2018
    Publication date: May 9, 2019
    Inventors: Gary A. Eiceman, Stephen J. Davila, Stefan R. Lukow, Hartwig Schmidt
  • Patent number: 10049868
    Abstract: An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: August 14, 2018
    Assignee: Rapiscan Systems, Inc.
    Inventors: Gary A. Eiceman, Stephen J. Davila, Stefan R. Lukow, Hartwig Schmidt
  • Publication number: 20180158665
    Abstract: An apparatus for detecting constituents in a sample includes first and second drift tubes defining first and second drift regions, and a controllable electric field device within a fragmentation region coupled to the first and second drift tubes. The apparatus also includes a first ion shutter positioned between the first drift and fragmentation regions. The apparatus further includes a control system configured to regulate the first ion shutter, thereby facilitating injection of a selected portion of ions from the first drift region into the fragmentation region. The control system is also configured to regulate the controllable device to modify the selected portion of ions to generate predetermined ion fragments within the fragmentation region, thereby facilitating injection of a selected portion of the predetermined fragmented ions into the second drift region. A method of detecting constituents in a sample is facilitated through such an apparatus.
    Type: Application
    Filed: December 6, 2016
    Publication date: June 7, 2018
    Inventors: Gary A. Eiceman, Stephen J. Davila, Stefan R. Lukow, Hartwig Schmidt
  • Patent number: 9508535
    Abstract: An ion mobility spectrometer having an ion source for generating ions; an ion detector for recording ions, and a number of substantially flat diaphragm electrodes arranged substantially perpendicular to a straight system axis that passes through the apertures in said diaphragms, with the diaphragms being arranged in a series of cells with each cell including an entrances and an exit diaphragm and a short region in between. The exit diaphragm of one cell is identical to the entrance diaphragm of the next cell, and the cells of said ion mobility spectrometer are grouped into three parts: an ion-beam forming region, an ion analyzing region, and a decelerating ion gate.
    Type: Grant
    Filed: March 15, 2012
    Date of Patent: November 29, 2016
    Assignee: SHIMADZU CORPORATION
    Inventors: Hermann Wollnik, Gary A. Eiceman
  • Publication number: 20150221489
    Abstract: An ion mobility spectrometer having an ion source for generating ions; an ion detector for recording ions, and a number of substantially flat diaphragm electrodes arranged substantially perpendicular to a straight system axis that passes through the apertures in said diaphragms, with the diaphragms being arranged in a series of cells with each cell including an entrances and an exit diaphragm and a short region in between. The exit diaphragm of one cell is identical to the entrance diaphragm of the next cell, and the cells of said ion mobility spectrometer are grouped into three parts: an ion-beam forming region, an ion analyzing region, and a decelerating ion gate.
    Type: Application
    Filed: March 15, 2012
    Publication date: August 6, 2015
    Inventors: Hermann Wollnik, Gary A. Eiceman
  • Patent number: 8969795
    Abstract: A filter for a mass- or mobility-spectrometer that bars gases or vapors of a high-pressure ion source, as well as ions of high mobility and charged droplets, from entering an evacuated mass spectrometer or a mobility spectrometer at a lower pressure than the filter. The buffer gas of the high pressure ion source is blown into the volume of this filter directly or through tubes from where buffer gas and embedded ions are sucked through the aperture of a diaphragm or through an aperture of a capillary mainly from an “extraction volume” filled with a separately supplied clean gas, into which ions of interest are pushed by electric fields formed by electrodes that are substantially rotational symmetric around the “extraction volume” and a substantially flat electrode with respect to an axis of ion extraction and the end of the capillary and the end of a coaxial tube surrounding the capillary.
    Type: Grant
    Filed: September 17, 2009
    Date of Patent: March 3, 2015
    Assignee: Shimadzu Corporation
    Inventors: Hermann Wollnik, Alexander Tarassov, Gary A. Eiceman
  • Patent number: 8592751
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, to sample pre-separation and amplification.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: November 26, 2013
    Assignee: DH Technologies Development Pte. Ltd.
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Lawrence A. Kaufman, Gary A. Eiceman
  • Patent number: 8410432
    Abstract: A ion mobility-based analyzer system including a first ion mobility-based filter for passing selected ions through a time-varying field where the time-varying field being compensated by an adjustable compensation setting. The analyzer also includes a second ion mobility-based filter for receiving a first portion of ions from the first ion mobility-based filter. The second ion mobility-based filter includes a voltage gradient for separating ions of the first portion of ions where the ions have associated retention times based on their times of flight through the voltage gradient. The second ion mobility-based filter includes a detector for detecting the ions at their retention times. The analyzer system further includes a display that displays the detected ions in a plot relating the retention times of the ions in the second ion mobility-based filter with compensation settings of the first ion mobility-based filter.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: April 2, 2013
    Assignee: DH Technologies Development Pte. Ltd.
    Inventors: Raanan A. Miller, Evgeny Krylova, Erkinjon G. Nazarov, Gary A. Eiceman, John A. Wright
  • Patent number: 8138474
    Abstract: A method for differential mobility separation of ions using digital-drive based high voltage fast switching electronics. The digital waveform delivered to the spectrometer is characterized by at least two substantially rectangular pulses of different amplitude and polarity. The control circuitry allows for waveform frequency, duty cycle and pulse amplitudes to be varied independently. Balanced as well as unbalanced asymmetric waveforms can be designed for optimum differential mobility separation of ions. The digital drive is designed for differential mobility spectrometers including parallel plate and segmented plate multipoles of planar symmetry, as well as multipoles of cylindrical symmetry, which may optionally be arranged in series. The use of the digital drive establishes alternating electric fields during which the displacement as a result of ion oscillation is determined by mobility coefficients.
    Type: Grant
    Filed: November 15, 2010
    Date of Patent: March 20, 2012
    Assignee: Shimadzu Corporation
    Inventors: Hermann Wollnik, Gary Eiceman, Dimitrios Papanastasiou
  • Publication number: 20120025070
    Abstract: A ion mobility-based analyzer system including a first ion mobility-based filter for passing selected ions through a time-varying field where the time-varying field being compensated by an adjustable compensation setting. The analyzer also includes a second ion mobility-based filter for receiving a first portion of ions from the first ion mobility-based filter. The second ion mobility-based filter includes a voltage gradient for separating ions of the first portion of ions where the ions have associated retention times based on their times of flight through the voltage gradient. The second ion mobility-based filter includes a detector for detecting the ions at their retention times. The analyzer system further includes a display that displays the detected ions in a plot relating the retention times of the ions in the second ion mobility-based filter with compensation settings of the first ion mobility-based filter.
    Type: Application
    Filed: August 8, 2011
    Publication date: February 2, 2012
    Applicant: DH Technologies Development PTE. Ltd.
    Inventors: Raanan A. Miller, Evgeny Krylov, Erkinjon G. Nazarov, Gary A. Eiceman, John A. Wright
  • Publication number: 20110174966
    Abstract: A filter for a mass- or mobility-spectrometer that bars gases or vapors of a high-pressure ion source, as well as ions of high mobility and charged droplets, from entering an evacuated mass spectrometer or a mobility spectrometer at a lower pressure than the filter. The buffer gas of the high pressure ion source is blown into the volume of this filter directly or through tubes from where buffer gas and embedded ions are sucked through the aperture of a diaphragm or through an aperture of a capillary mainly from an “extraction volume” filled with a separately supplied clean gas, into which ions of interest are pushed by electric fields formed by electrodes that are substantially rotational symmetric around the “extraction volume” and a substantially flat electrode with respect to an axis of ion extraction and the end of the capillary and the end of a coaxial tube surrounding the capillary.
    Type: Application
    Filed: September 17, 2009
    Publication date: July 21, 2011
    Applicant: SHIMADZU CORPORATION
    Inventors: Hermann Wollnik, Alexander Tarassov, Gary A. Eiceman
  • Patent number: 7902498
    Abstract: The invention relates generally to ion mobility based systems, methods and devices for analyzing samples and, more particularly, to sample pre-separation and amplification.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: March 8, 2011
    Assignee: DH Technologies Development PTE. Ltd.
    Inventors: Raanan A. Miller, Erkinjon G. Nazarov, Lawrence A. Kaufman, Gary A. Eiceman