Patents by Inventor Gary A. Nichols

Gary A. Nichols has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9168227
    Abstract: A microsphere and methods for forming the same are disclosed. The microsphere includes modified cellulose and at least one first microsphere disposed within a multi-encapsulating microsphere, the at least one first microsphere comprising at least one first hydrogel precursor; and at least one second microsphere disposed within the multi-encapsulating microsphere, the at least one second microsphere comprising at least one second hydrogel precursor cross-linkable with the at least one first hydrogel precursor upon degradation of the at least one first microsphere and the at least one second microsphere.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: October 27, 2015
    Assignee: Covidien LP
    Inventors: Phillip D. Blaskovich, Clifford J. Herman, Gary A. Nichols, Rachit Ohri, Lan Pham
  • Publication number: 20140079790
    Abstract: A microsphere and methods for forming the same are disclosed. The microsphere includes modified cellulose and at least one of precursors for is-situ polymerization or endothermic/exothermic reactions.
    Type: Application
    Filed: September 12, 2013
    Publication date: March 20, 2014
    Applicant: Confluent Surgical, Inc.
    Inventors: Phillip D. Blaskovich, Clifford J. Herman, Gary A. Nichols, Rachit Ohri, Lan Pham
  • Patent number: 8399475
    Abstract: The present invention relates to novel crystalline forms of naltrexone hydrochloride including hydrated and solvated forms and a novel amorphous form. The invention also describes methods of preparing the various crystalline forms. The present invention also relates to pharmaceutical compositions containing crystalline and amorphous forms of naltrexone hydrochloride, as well as methods of treating addictive behavior by administering the pharmaceutical compositions.
    Type: Grant
    Filed: April 10, 2008
    Date of Patent: March 19, 2013
    Assignee: Mallinckrodt LLC
    Inventors: Gary A. Nichols, Michelle R. Menze, Anthony Mannino
  • Patent number: 8383649
    Abstract: The present invention relates to novel crystalline forms of naltrexone methobromide including hydrated and solvated forms. The invention also describes methods of preparing the various crystalline forms. The present invention also relates to pharmaceutical compositions containing crystalline forms of naltrexone methobromide, as well as methods of treating or preventing opioid induced side effects by administering the pharmaceutical compositions.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: February 26, 2013
    Assignee: Mallinckrodt LLC
    Inventors: Gary A. Nichols, Robert E. Halvachs, Gary L. Cantrell, Kevin R. Roesch, Joseph P. Haar, Jr.
  • Patent number: 8227483
    Abstract: The present invention provides polymorphs of 6-beta-naltrexol and process for their preparation. In particular, the present invention provides crystalline forms of the free base of 6-beta-naltrexol and processes for their preparation. The present invention also provides crystalline and amorphous forms of the hydrochloride salt of 6-beta-naltrexol and processes for their preparation.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: July 24, 2012
    Assignee: Mallinckrodt LLC
    Inventors: Jian Bao, Gary A. Nichols
  • Publication number: 20100324078
    Abstract: The present invention relates to novel crystalline forms of naltrexone methobromide including hydrated and solvated forms. The invention also describes methods of preparing the various crystalline forms. The present invention also relates to pharmaceutical compositions containing crystalline forms of naltrexone methobromide, as well as methods of treating or preventing opioid induced side effects by administering the pharmaceutical compositions.
    Type: Application
    Filed: June 25, 2008
    Publication date: December 23, 2010
    Inventors: Gary A. Nichols, Robert E. Halvachs, Gary L. Cantrell, Kevin R. Roesch, Joseph P. Haar, JR.
  • Publication number: 20100316585
    Abstract: The invention provides lubricant compositions comprising magnesium stearate dihydrate. The lubricant compositions may be used to lubricate a variety of solid materials that are used in industrial or consumer products.
    Type: Application
    Filed: February 11, 2009
    Publication date: December 16, 2010
    Inventors: Stephen H. Wu, Brian K. Cheng, Gary A. Nichols, Jae H. Park
  • Publication number: 20100120814
    Abstract: The present invention relates to novel crystalline forms of naltrexone hydrochloride including hydrated and solvated forms and a novel amorphous form. The invention also describes methods of preparing the various crystalline forms. The present invention also relates to pharmaceutical compositions containing crystalline and amorphous forms of naltrexone hydrochloride, as well as methods of treating addictive behavior by administering the pharmaceutical compositions.
    Type: Application
    Filed: April 10, 2008
    Publication date: May 13, 2010
    Inventors: Gary A. Nichols, Michelle R. Menze, Anthony Mannino
  • Publication number: 20100113831
    Abstract: A highly pure crystalline form of benzphetamine hydrochloride and methods for the purification and crystallization of benzphetamine hydrochloride in high yield are disclosed.
    Type: Application
    Filed: October 17, 2006
    Publication date: May 6, 2010
    Applicant: MALLINCKRODT INC.
    Inventors: Keith G. Tomazi, Gary A. Nichols, Michelle R. Menze, Dennis J. Kalota
  • Publication number: 20100076198
    Abstract: The present invention provides crystalline forms of fentanyl alkaloid and methods for preparing crystalline forms of fentanyl alkaloid.
    Type: Application
    Filed: September 16, 2009
    Publication date: March 25, 2010
    Applicant: Mallinckrodt Inc.
    Inventor: Gary A. Nichols
  • Publication number: 20100076007
    Abstract: The present invention provides polymorphs of 6-beta-naltrexol and process for their preparation. In particular, the present invention provides crystalline forms of the free base of 6-beta-naltrexol and processes for their preparation. The present invention also provides crystalline and amorphous forms of the hydrochloride salt of 6-beta-naltrexol and processes for their preparation.
    Type: Application
    Filed: September 21, 2009
    Publication date: March 25, 2010
    Applicant: Mallinckrodt Inc.
    Inventors: Jian Bao, Gary A. Nichols
  • Publication number: 20100056574
    Abstract: The present invention provides crystalline forms of sufentanil citrate and methods for preparing crystalline forms of sufentanil citrate.
    Type: Application
    Filed: August 25, 2009
    Publication date: March 4, 2010
    Applicant: Mallinckrodt Inc.
    Inventors: Brian K. Cheng, Gary A. Nichols
  • Publication number: 20090232896
    Abstract: The invention provides lubricant compositions comprising magnesium stearate dihydrate. The lubricant compositions may be used to lubricate a variety of bioactive formulations including pharmaceutical compositions.
    Type: Application
    Filed: February 11, 2009
    Publication date: September 17, 2009
    Applicant: Mallinckrodt Inc.
    Inventors: Stephen H. Wu, Brian K. Cheng, Gary A. Nichols, Jae H. Park
  • Patent number: 7503311
    Abstract: An electronic throttle control system and method for detecting a throttle plate obstruction when the ignition key is on and the engine is either not running or running, and for clearing the throttle plate obstruction before a fault setting is set by the ECU.
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: March 17, 2009
    Assignee: Delphi Technologies, Inc.
    Inventors: Gary A. Nichols, Daniel L. McKay
  • Publication number: 20080319197
    Abstract: The present invention relates to a crystalline polymorphic form of remifentanil hydrochloride. The invention also describes methods of preparing a polymorphic form of remifentanil hydrochloride.
    Type: Application
    Filed: January 19, 2007
    Publication date: December 25, 2008
    Inventors: Brian K. Cheng, Gary A. Nichols, Catherine E. Thomasson
  • Publication number: 20080251048
    Abstract: An electronic throttle control system and method for detecting a throttle plate obstruction when the ignition key is on and the engine is either not running or running, and for clearing the throttle plate obstruction before a fault setting is set by the ECU.
    Type: Application
    Filed: April 13, 2007
    Publication date: October 16, 2008
    Inventors: Gary A. Nichols, Daniel L. McKay
  • Patent number: 7434566
    Abstract: An electronic throttle control system and method which prevents obstructions from forming around a throttle plate during engine soak.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: October 14, 2008
    Assignee: Delphi Technologies, Inc.
    Inventors: Daniel L. McKay, Gary A. Nichols, Carelton Williams Guillaume
  • Publication number: 20080098986
    Abstract: An electronic throttle control system and method which prevents obstructions from forming around a throttle plate during engine soak.
    Type: Application
    Filed: October 31, 2006
    Publication date: May 1, 2008
    Inventors: Daniel L. McKay, Gary A. Nichols, Carelton Williams Guillaume
  • Publication number: 20070281957
    Abstract: The present invention relates to novel crystalline polymorphic forms of levorphanol including hydrated, solvated, and non-hydrated (non-solvated) forms. The invention also describes methods of preparing the various polymorphic forms. The present invention also relates to pharmaceutical compositions containing crystalline polymorphs of levorphanol, as well as methods of relieving pain by administering the pharmaceutical compositions.
    Type: Application
    Filed: May 24, 2007
    Publication date: December 6, 2007
    Applicant: Mallinckrodt Inc.
    Inventors: Sidney Liang, Gary A. Nichols, Michelle R. Menze
  • Patent number: 7021284
    Abstract: A method for throttle progression control to minimize tip-in noise of an internal combustion engine by allowing the engine to receive only the required air for the commanded engine acceleration. The method comprises the steps of a) providing an electronically controlled throttle body and valve, b) providing an electronic control module, c) determining the engine air flow required to satisfy a desired engine acceleration, d) providing an input to the electronic control module corresponding to the engine air flow required, e) programming the electronic control module to limit the inflow of air during engine acceleration to match the engine air flow required for achieving said desired engine acceleration, and f) actuating the throttle body and valve to provide the limited air flow through the throttle body during the desired engine acceleration.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: April 4, 2006
    Assignee: Delphi Technologies, Inc.
    Inventors: Keith A. Confer, Gary A. Nichols, Christopher H. Knieper