Abstract: The invention provides a microscaffold comprising a porous particle, which particle: (a) comprises a three dimensional network of fibres, which fibres comprise a polymer, and (b) has a particle size of less than or equal to 2000 ?m. Further provided is a composition, which composition comprises a microscaffold of the invention or a plurality of microscaffolds of the invention. The invention also provides a multi-well assay plate comprising: a plurality of sample wells, and a composition of the invention in at least one of the sample wells. The microscaffold, composition or multi-well plate may be used for regenerative medicine, tissue engineering, screening compounds for biological use or drug screening. The microscaffold may further comprise a magnetic material, and the invention additionally provides a method of manipulating one or more such microscaffolds.