Abstract: A ventilation screed comprising: an attachment flange having a top portion and a bottom portion; a drip edge protruding from the attachment flange and a return leg that protrudes back from the drip edge, wherein the drip edge is angled downward in a first direction and the return leg is angled downward in a second direction; a drainage cavity protrusion protruding from the attachment flange above the drip edge, wherein the drainage cavity protrusion has an L-shaped drainage trough portion having at least one drainage opening in a bottom portion and a substantially vertical portion with a top end and a bottom end in communication with the bottom portion, an upper ground portion in communication with the top end of the substantially vertical portion of the L-shaped drainage trough portion extending outward from the substantially vertical portion and a drainage cavity shroud extending substantially downward from the upper ground portion.

Abstract: Disclosed herein are methods and compositions for inactivating TCR genes, using engineered nucleases comprising at least one DNA binding domain and a cleavage domain or cleavage half-domain in conditions able to preserve cell viability. Polynucleotides encoding nucleases, vectors comprising polynucleotides encoding nucleases and cells comprising polynucleotides encoding nucleases and/or cells comprising nucleases are also provided. Disclosed herein are also methods and compositions for expressing a functional exogenous TCR in the absence of endogenous TCR expression in T lymphocytes, including lymphocytes with a central memory phenotype. Polynucleotides encoding exogenous TCR, vectors comprising polynucleotides encoding exogenous TCR and cells comprising polynucleotides encoding exogenous TCR and/or cells comprising exogenous TCR are also provided.

Abstract: A computer-implemented system and method for dynamically generating library reports is provided. An application server may acquire and receive a plurality of raw item datasets each associated with a library item from multiple sources; and map each of the plurality of raw item datasets to a set of parameters to generate a mapped item dataset for each library item by identifying a unique identifier for each raw item dataset associated with each library item. and process a plurality of mapped item datasets to output processed item datasets that corresponds to one or more metrics. The application server may dynamically generate one or more library reports by applying a machine learning algorithm on the processed item datasets. The machine learning algorithm is executed to determine a priority of generating each library report based at least on a user request.

Abstract: Methods are disclosed of treating or preventing hypotension (e.g., neurogenic orthostatic hypotension or postprandial hypotension) or portal hypertension (e.g., bleeding esophageal varices associated with portal hypertension) or ascites (e.g., ascites associated with liver cirrhosis), by oral administration to affected subjects of compositions comprising a therapeutically effective amount of terlipressin or a pharmaceutically acceptable salt thereof.

Abstract: Innovations in signaling of reference picture list (“RPL”) modification information. For example, a video encoder evaluates a condition that depends at least in part on a variable indicating a number of total reference pictures. Depending on the results of the evaluation, the encoder signals in a bitstream a flag that indicates whether an RPL is modified according to syntax elements explicitly signaled in the bitstream. A video decoder evaluates the condition and, depending on results of the evaluation, parses from a bitstream a flag that indicates whether an RPL is modified according to syntax elements explicitly signaled in the bitstream. The condition can be evaluated as part of processing for an RPL modification structure that includes the flag, or as part of processing for a slice header. The encoder and decoder can also evaluate other conditions that affect syntax elements for list entries of the RPL modification information.

Abstract: Atmospheric Triphasic Chromatography (ATC) method comprising the steps introducing a raw plant material containing cannabinoids into a non-polar solvent, dissolving the cannabinoids extracted from the raw plant material in the non-polar solvent and removing the raw plant material to obtain a target solution, performing potency analysis and cannabinoid extract profile analysis of the target solution. The method further includes the steps of preparing an aqueous caustic solution and mixing the target solution with the aqueous caustic solution to obtain a mixture followed by separating the mixture into a first phase solution and a second phase solution, and removing the first phase solution to obtain a caustic target solution and acidifying the caustic target solution to produce precipitation of an undesirable compound in the caustic target solution.

Abstract: A method performed by a computing device includes obtaining impaired content for a topic that includes a series of words, and determining a set of identigens for each word of the series of words to produce sets of identigens. The method further includes interpreting, using identigen pairing rules of a knowledge database, the sets of identigens to determine a most likely meaning interpretation of the impaired content and produce an interim entigen group. The method further includes recovering an improved entigen group for the topic from the knowledge database utilizing the interim entigen group and based on a knowledge defect of the interim entigen group caused by an impairment of the impaired content.

Abstract: A system delivers gas-enriched blood or liquid within the vasculature of a patient while partially obstructing a flow of blood within the vasculature of the patient. The system may include a first catheter configured for inserting into a vasculature of a patient to deliver gas-enriched blood or liquid to a region of the vasculature of the patient. The system may include a second catheter configured for inserting into the vasculature of the patient. The second catheter includes lumens and an occlusion structure configured to partially obstruct a flow of blood within the vasculature of the patient while allowing the first catheter to deliver the gas-enriched blood or liquid to the region of the vasculature, and to divert the blood flow to the region where the gas-enriched blood or liquid is delivered.

Abstract: A pancreatic stent includes a main body convertible between a compressed configuration for delivery and an expanded configuration once deployed, the main body including an inner surface defining a stent lumen and an outer surface. A plurality of drainage features are formed within the outer surface of the main body, the plurality of drainage features permitting placement of the pancreatic stent within a patient's pancreas without blocking side branches of the pancreas.

Abstract: A packer including a packer element, a mandrel about which the packer element is disposed, an intensifier configuration on the mandrel.

Abstract: A combustor liner assembly includes a first liner panel that has a first forward end and a first aft end. A second liner panel has a second forward end and a second aft end. A support band has a plurality of circumferentially spaced holes. The support band is arranged between the first liner panel and the second liner panel. The support band has a protrusion with a first angled surface and a second angled surface. The first angled surface is in engagement with the first aft end and the second angled surface in engagement with the second forward end.

Abstract: A method for execution by a computing device of a storage network includes determining an encoded data slice reduction scheme for a set of encoded data slices stored in a set of storage units of the storage network, where a data segment of data is encoded into the set of encoded data slices in accordance with encoding parameters, and where the encoding parameters include a pillar width number and a decode threshold number. The method further includes maintaining storage of the set of encoded data slices in accordance with the encoded data slice reduction scheme, where the maintaining storage includes keeping a number of encoded data slices of the set of encoded data slices equal to or greater than the decode threshold number and less than the pillar width number.

Abstract: A water-soluble multicompartment unit dose article having a weight ratio of laundry detergent to total water-soluble film in the water-soluble multicompartment unit dose article of at least 45:1.

Abstract: An outlet gate/gate assembly having a trough section having opposing slanted sheets, and an end sheet at ends thereof, the trough section defining a trough, and each end sheet providing a discharge opening fluidly connected with the trough; and an end tube/end adapter assembly fluidly connected with each end sheet, the end tube/end adapter assembly comprising an end adapter, an outlet cap, and an end tube seal/end adapter gasket, the end tube seal/end adapter gasket positioned between the end sheet and the end adapter or within the end adapter, wherein the end tube seal/end adapter gasket comprises a base plate and a primary/main flap, the base plate defining a discharge opening, and the primary/main flap biased to, when closed, completely cover the discharge opening.

Abstract: A rain screen metal wall panel system is disclosed herein. Specifically, the system is directed to a metal wall panel assembly that includes a plurality of metal panels with a tab and slot design that accurately aligns the panels in three axes simultaneously. This increases the speed of installation while maintaining a properly aligned finished wall surface, join distances, and reduces cost by eliminating unnecessary clips and rails. The bottom panel(s) of the metal wall panel system of at least one embodiment includes a flat or generally planar bottom edge, with an attachment zee connection to the support structure.

Abstract: A retractor assembly and minimally invasive surgical techniques and implants. Such embodiments include techniques and implants for provision of therapy to a spine from a lateral approach. Embodiments of the invention include minimally invasive surgical techniques using one or more extended retractors to create an extended access route such as the non-limiting example of lateral access to the spine.

Abstract: A braking system for safely collecting brake dust produced by operation of a braking mechanism. The braking system comprises a collector apparatus coupled with a braking mechanism. The collector apparatus is able to include a shroud that surrounds the braking mechanism and a catch element coupled with the shroud for collecting brake dust exiting the shroud. As a result, when coupled with the braking mechanism, the collector apparatus is able to ensure that most or all brake dust, such as copper or other particles from the braking mechanism that break off from the breaking mechanism during operation of the braking mechanism, are removed from the braking mechanism and collected by the filter/catch of the collector mechanism.

Abstract: A system and method for providing asymmetrical filtering to improve performance in the presence of wideband interference is herein disclosed. According to one embodiment, a method for a global navigation satellite system (GNSS) receiver includes detecting wideband interference in a received target GNSS signal, and applying an asymmetric filter to the received target GNSS signal to mitigate the detected wideband interference.

Abstract: Medical devices can perform a plurality of functions, such as sensing, monitoring, deriving and/or calculating various physiological statuses of a patient (e.g., blood pressure, temperature, respiration rate, etc.). Medical devices can also be used to image part or all of a patient's body, to deliver a treatment, or to manage information related to a patient's care. The present disclosure is directed at one or more devices that perform these functions using a plurality of processing circuits, wherein each processing circuit has a timing circuit with a local clock. These processing circuits can be connected via a network, and each timing circuit can communicate with at least one other timing circuit in order to detect and correct time-differences between their local clocks. In this way, multiple processing circuits can be synchronized with each other to facilitate diagnosis or treatment of a patient's condition, or other aspects of a patient's care.