Patents by Inventor Gary Anthony PESTANO

Gary Anthony PESTANO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMAGE ACQUISITION METHODS FOR SIMULTANEOUSLY DETECTING GENETIC REARRANGEMENT AND NUCLEAR MORPHOLOGY
    Publication number: 20220389523
    Abstract: In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or progression using a multivariate image data and statistical analysis of in-situ molecular markers and morphological characteristics in the same cells of a biological sample suspected of b cancer. This analysis takes place after a single acquisition that obtains the molecular and anatomic morphology data in parallel. The analysis compares specific morphological and molecular markers to known samples exhibiting particular genetic drivers of the cancer. This method provides statistical information that allows for an increased confidence in the identification of specific molecular drivers of the cancer.
    Type: Application
    Filed: August 5, 2022
    Publication date: December 8, 2022
    Inventors: Francesca Demichelis, Karl Garsha, Phillip C. Miller, Ray B. Nagle, Michael Otter, Gary Anthony Pestano, Mark Rubin
  • Image acquisition methods for simultaneously detecting genetic rearrangement and nuclear morphology
    Patent number: 11441189
    Abstract: In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or progression using a multivariate image data and statistical analysis of in-situ molecular markers and morphological characteristics in the same cells of a biological sample suspected of b cancer. This analysis takes place after a single acquisition that obtains the molecular and anatomic morphology data in parallel. The analysis compares specific morphological and molecular markers to known samples exhibiting particular genetic drivers of the cancer. This method provides statistical information that allows for an increased confidence in the identification of specific molecular drivers of the cancer.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: September 13, 2022
    Assignees: Ventana Medical Systems, Inc., Cornell University
    Inventors: Francesca Demichelis, Karl Garsha, Phillip C. Miller, Ray B. Nagle, Michael Otter, Gary Anthony Pestano, Mark Rubin
  • SPECTRAL IMAGING FOR MEASUREMENT OF NUCLEAR PATHOLOGY FEATURES IN CANCER CELLS PREPARED FOR IN SITU ANALYSIS
    Publication number: 20180291464
    Abstract: In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or progression using a multivariate image data and statistical analysis of in-situ molecular markers and morphological characteristics in the same cells of a biological sample suspected of b cancer. This analysis takes place after a single acquisition that obtains the molecular and anatomic morphology data in parallel. The analysis compares specific morphological and molecular markers to known samples exhibiting particular genetic drivers of the cancer. This method provides statistical information that allows for an increased confidence in the identification of specific molecular drivers of the cancer.
    Type: Application
    Filed: April 12, 2018
    Publication date: October 11, 2018
    Inventors: Francesca Demichelis, Karl Garsha, Phillip C. Miller, Ray B. Nagle, Michael Otter, Gary Anthony Pestano, Mark Rubin
  • Spectral imaging for measurement of nuclear pathology features in cancer cells prepared for in situ analysis
    Patent number: 9951388
    Abstract: In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or progression using a multivariate image data and statistical analysis of in-situ molecular markers and morphological characteristics in the same cells of a biological sample suspected of b cancer. This analysis takes place after a single acquisition that obtains the molecular and anatomic morphology data in parallel. The analysis compares specific morphological and molecular markers to known samples exhibiting particular genetic drivers of the cancer. This method provides statistical information that allows for an increased confidence in the identification of specific molecular drivers of the cancer.
    Type: Grant
    Filed: May 7, 2012
    Date of Patent: April 24, 2018
    Assignees: Ventana Medical Systems, Inc., Cornell University
    Inventors: Francesca Demichelis, Karl Garsha, Phillip C. Miller, Ray B. Nagle, Michael Otter, Gary Anthony Pestano, Mark Rubin
  • Spectral Imaging for Measurement of Nuclear Pathology Features in Cancer Cells Prepared for In Situ Analysis
    Publication number: 20150197811
    Abstract: In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or progression using a multivariate image data and statistical analysis of in-situ molecular markers and morphological characteristics in the same cells of a biological sample suspected of b cancer. This analysis takes place after a single acquisition that obtains the molecular and anatomic morphology data in parallel. The analysis compares specific morphological and molecular markers to known samples exhibiting particular genetic drivers of the cancer. This method provides statistical information that allows for an increased confidence in the identification of specific molecular drivers of the cancer.
    Type: Application
    Filed: April 23, 2013
    Publication date: July 16, 2015
    Applicants: CORNELL UNIVERSITY, VENTANA MEDICAL SYSTEMS, INC.
    Inventors: Francesca Demichelis, Karl Garsha, Phillip C. Miller, Ray B. Nagle, Michael Otter, Gary Anthony Pestano, Mark Rubin
  • Spectral Imaging for Measurement of Nuclear Pathology Features in Cancer Cells Prepared for In Situ Analysis
    Publication number: 20140296088
    Abstract: In general, the presently disclosed technology relates to identification of cancer subtypes. More specifically, the technology relates to methods for determining molecular drivers of cancer and/or progression using a multivariate image data and statistical analysis of in-situ molecular markers and morphological characteristics in the same cells of a biological sample suspected of b cancer. This analysis takes place after a single acquisition that obtains the molecular and anatomic morphology data in parallel. The analysis compares specific morphological and molecular markers to known samples exhibiting particular genetic drivers of the cancer. This method provides statistical information that allows for an increased confidence in the identification of specific molecular drivers of the cancer.
    Type: Application
    Filed: April 23, 2013
    Publication date: October 2, 2014
    Applicants: CORNELL UNIVERSITY, VENTANA MEDICAL SYSTEMS, INC.
    Inventors: Francesca Demichelis, Karl Garsha, Phillip C. Miller, Ray B. Nagle, Michael Otter, Gary Anthony Pestano, Mark Rubin
  • Reagents And Methods For Cancer Prognosis And Pathological Staging
    Publication number: 20100184099
    Abstract: This invention provides reagents and methods for assessing tumor progression using tissue or tumor cell-containing samples from an individual. The invention also provides reagents and methods for assessing response to chemotherapy.
    Type: Application
    Filed: January 19, 2010
    Publication date: July 22, 2010
    Inventors: Gary Anthony PESTANO, Linda Kay Samadzadeh