Patents by Inventor Gary B. Calandra

Gary B. Calandra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS TO MOBILIZE PROGENITOR/STEM CELLS
    Publication number: 20190216773
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: August 21, 2018
    Publication date: July 18, 2019
    Inventors: Gary J. BRIDGER, Michael J. ABRAMS, Geoffrey W. HENSON, Ronald Trevor MACFARLAND, Gary B. CALANDRA, Hal E. BROXMEYER, David C. DALE
  • METHODS TO MOBILIZE PROGENITOR/STEM CELLS
    Publication number: 20170049747
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: March 18, 2016
    Publication date: February 23, 2017
    Inventors: Gary J. BRIDGER, Michael J. ABRAMS, Geoffrey W. HENSON, Ronald Trevor MACFARLAND, Gary B. CALANDRA, Hal E. BROXMEYER, David C. DALE
  • METHODS TO MOBILIZE PROGENITOR/STEM CELLS
    Publication number: 20150246019
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: October 3, 2014
    Publication date: September 3, 2015
    Inventors: Gary J. BRIDGER, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor Macfarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • METHODS TO MOBILIZE PROGENITOR/STEM CELLS
    Publication number: 20110129448
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: February 8, 2011
    Publication date: June 2, 2011
    Applicant: Genzyme Corporation
    Inventors: Gary J. BRIDGER, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • Methods to mobilize progenitor/stem cells
    Patent number: 7935692
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: May 3, 2011
    Assignee: Genzyme Corporation
    Inventors: Gary J. Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • Methods to mobilize progenitor/stem cells
    Patent number: 7897590
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: March 1, 2011
    Assignee: Genzyme Corporation
    Inventors: Gary J. Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • Methods to mobilize progenitor/stem cells
    Patent number: 7169750
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed. Preferred embodiments of such compounds are of the formula Z-linker-Z? ??(1) or pharmaceutically acceptable salt thereof wherein Z is of the formula wherein A comprises a monocyclic or bicyclic fused ring system containing at least one N and B is H or an organic moiety of 1–20 atoms, Z? is of the formula —Ar(Y)j; wherein Ar is an aromatic or heteroaromatic moiety, and each Y is independently a non-interfering substituent and j is 0–3; and “linker” represents a bond, alkylene (1–6C) or may comprise aryl, fused aryl, oxygen atoms contained in an alkylene chain, or may contain keto groups or nitrogen or sulfur atoms.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: January 30, 2007
    Assignee: Anormed, Inc.
    Inventors: Gary Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald T. MacFarland, Gary B. Calandra
  • Methods to mobilize progenitor/stem cells
    Patent number: 6987102
    Abstract: Certain nitrogen-containing compounds that bind the chemokine receptor CXCR4 are able to mobilize progenitor and/or stem cells into the peripheral blood to permit harvesting them for stem cell transplantation.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: January 17, 2006
    Assignee: Anormed, Inc.
    Inventors: Gary J. Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra, Hal E. Broxmeyer, David C. Dale
  • Methods to mobilize progenitor/stem cells
    Publication number: 20030130250
    Abstract: Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed.
    Type: Application
    Filed: July 30, 2002
    Publication date: July 10, 2003
    Inventors: Gary J. Bridger, Michael J. Abrams, Geoffrey W. Henson, Ronald Trevor MacFarland, Gary B. Calandra
  • Method for preventing zoster or alleviating varicella related post-herpetic neuralgia
    Patent number: 6214354
    Abstract: Herpes Zoster, or varicella related post herpetic neuralgia is alleviated by immunizing people at risk of developing herpes zoster with varicella zoster virus (VZV) antigen.
    Type: Grant
    Filed: August 11, 1999
    Date of Patent: April 10, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Gary B. Calandra, Philip J. Provost, Myron J. Levin, C. Jo White
  • Method for alleviating varicella related post-herpetic neuralgia
    Patent number: 5997880
    Abstract: Herpes Zoster, or varicella related post herpetic neuralgia is alleviated by immunizing people at risk of developing herpes zoster with varicella zoster virus (VZV) antigen.
    Type: Grant
    Filed: March 18, 1994
    Date of Patent: December 7, 1999
    Assignees: Merck & Co., Inc., University of Colorado
    Inventors: Gary B. Calandra, Philip J. Provost, Myron J. Levin, C. Jo White