Patents by Inventor Gary B. Ruvkun

Gary B. Ruvkun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAROTENOIDS FOR TREATING OR PREVENTING NAUSEA
    Publication number: 20210230660
    Abstract: Methods and compositions comprising carotenoids for the treatment or prevention of nausea, e.g., chemotherapy-induced nausea and vomiting.
    Type: Application
    Filed: April 12, 2021
    Publication date: July 29, 2021
    Applicant: The General Hospital Corporation
    Inventors: Gary B. RUVKUN, Jothi Amaranath GOVINDAN, Elamparithi JAYAMANI
  • Carotenoids for treating or preventing nausea
    Patent number: 11001870
    Abstract: Methods and compositions comprising carotenoids for the treatment or prevention of nausea, e.g., chemotherapy-induced nausea and vomiting.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: May 11, 2021
    Assignee: THE GENERAL HOSPITAL CORPORATION
    Inventors: Gary B. Ruvkun, Jothi Amaranath Govindan, Elamparithi Jayamani
  • CAROTENOIDS FOR TREATING OR PREVENTING NAUSEA
    Publication number: 20200255882
    Abstract: Methods and compositions comprising carotenoids for the treatment or prevention of nausea, e.g., chemotherapy-induced nausea and vomiting.
    Type: Application
    Filed: May 10, 2019
    Publication date: August 13, 2020
    Inventors: Gary B. Ruvkun, Jothi Amaranath Govindan, Elamparithi Jayamani
  • Tools and Methods for Targeting Oligonucleotide Repeat RNA Toxicity
    Publication number: 20170023551
    Abstract: Described are Caenorhabditis elegans (C. elegans) strains exhibiting an RNA toxicity phenotype. The C. elegans strains comprise a detectable reporter gene expressed in one or more cell types, with the expressed reporter gene RNA having in instance of at least fifty oligonucleotide repeats (e.g., trinucleotide repeats). Exemplary C. elegans reporter strains are generated that exhibit phenotypes characteristic of the human disorder Myotonic Dystrophy 1. The C. elegans strains are amenable for high-throughput screening applications, for both gene target as well as small molecule identification.
    Type: Application
    Filed: July 20, 2016
    Publication date: January 26, 2017
    Inventors: Gary B. Ruvkun, Susana Garcia
  • Methods of screening compounds useful for prevention of infection or pathogenicity
    Patent number: 7166270
    Abstract: Screening procedures are disclosed for identifying compounds useful for inhibiting infection or pathogenicity. Methods are also disclosed for identifying pathogenic virulence factors.
    Type: Grant
    Filed: November 3, 1997
    Date of Patent: January 23, 2007
    Assignees: The Netherlands Cancer Institute, The General Hospital Corporation
    Inventors: Frederick M. Ausubel, Laurence G. Rahme, Man-Wah Tan, Gary B. Ruvkun, Shalina Mahajan-Miklos, Annegien Broeks, Ronald H. A. Plasterk, Georg Jander, Jacqueline Heard
  • Methods of screening compounds useful for prevention of infection or pathogenicity
    Patent number: 6905670
    Abstract: Screening procedures are disclosed for identifying compounds useful for inhibiting fungal infection or pathogenicity. Methods are also disclosed for identifying fungal pathogenic virulence factors.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: June 14, 2005
    Assignee: The General Hospital Corporation
    Inventors: Frederick M. Ausubel, Stephen B. Calderwood, Eleftherios Mylonakis, Andrew Diener, Julia Plotnikova, Costi D. Sifri, Laurence G. Rahme, Man-Wah Tan, Gary B. Ruvkun, Georg Jander, Jacqueline Heard
  • Methods of screening compounds useful for prevention of infection or pathogenicity
    Publication number: 20030086871
    Abstract: Screening procedures are disclosed for identifying compounds useful for inhibiting fungal infection or pathogenicity. Methods are also disclosed for identifying fungal pathogenic virulence factors.
    Type: Application
    Filed: May 22, 2002
    Publication date: May 8, 2003
    Inventors: Frederick M. Ausubel, Stephen B. Calderwood, Eleftherios Mylonakis, Andrew Diener, Julia Plotnikova, Costi D. Sifri, Laurence G. Rahme, Man-Wah Tan, Gary B. Ruvkun, Georg Jander, Jacqueline Heard
  • Methods of screening compounds useful for prevention of infection or pathogenicity
    Patent number: 6461854
    Abstract: Screening procedures are disclosed for identifying compounds useful for inhibiting infection or pathogenicity. Methods are also disclosed for identifying pathogenic virulence factors.
    Type: Grant
    Filed: March 28, 1995
    Date of Patent: October 8, 2002
    Assignee: The General Hospital Corporation
    Inventors: Frederick M. Ausubel, Laurence G. Rahme, Man-Wah Tan, Gary B. Ruvkun