Patents by Inventor Gary Barbera

Gary Barbera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Solubility of hydrophobic drugs with a compound having a carboxylic acid moiety
    Patent number: 7939104
    Abstract: A pharmaceutical composition having improved solubility comprising a hydrophobic drug or pharmaceutically acceptable salt thereof and a compound having at least one carboxylic acid moiety, wherein the molar ratio of the compound having at least one carboxylic acid moiety to the hydrophobic drug or pharmaceutically acceptable salt thereof is from about 0.1:1 to about 25:1. The pharmaceutical composition exhibits rapid dissolution upon contact with physiological solvents, such as water, saliva or gastrointestinal fluids.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: May 10, 2011
    Assignee: Sandoz AG
    Inventors: Gary Barbera, Chetan Chhabildas Doshi, Mahendra R Patel, Pablo Davila, Satishkumar Ambalal Patel
  • Solubility of hydrophobic drugs with a compound having a carboxylic acid moiety
    Patent number: 7727556
    Abstract: A pharmaceutical composition having improved solubility comprising a hydrophobic drug or pharmaceutically acceptable salt thereof and a compound having at least one carboxylic acid moiety, wherein the molar ratio of the compound having at least one carboxylic acid moiety to the hydrophobic drug or pharmaceutically acceptable salt thereof is from about 0.1:1 to about 25:1. The pharmaceutical composition exhibits rapid dissolution upon contact with physiological solvents, such as water, saliva or gastrointestinal fluids.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: June 1, 2010
    Assignee: Sandoz AG
    Inventors: Gary Barbera, Chetan Chhabildas Doshi, Mahendra R Patel, Pablo Davila, Satishkumar Ambalal Patel
  • Solubility of hydrophobic drugs with a compound having a carboxylic acid moiety
    Publication number: 20080146581
    Abstract: A pharmaceutical composition having improved solubility comprising a hydrophobic drug or pharmaceutically acceptable salt thereof and a compound having at least one carboxylic acid moiety, wherein the molar ratio of the compound having at least one carboxylic acid moiety to the hydrophobic drug or pharmaceutically acceptable salt thereof is from about 0.1:1 to about 25:1. The pharmaceutical composition exhibits rapid dissolution upon contact with physiological solvents, such as water, saliva or gastrointestinal fluids.
    Type: Application
    Filed: February 15, 2008
    Publication date: June 19, 2008
    Applicant: Sandoz AG
    Inventors: Gary Barbera, Chetan Chhabildas Doshi, Mahendra R. Patel, Pablo Davila, Satishkumar Ambalal Patel
  • Stabilized azithromycin composition
    Publication number: 20080096831
    Abstract: A stabilized azithromycin composition comprising azithromycin monohydrate, and about 5 to about 15 weight percent, based on the total weight of the composition, of water. The present inventors have unexpectedly determined that a certain amount of water is necessary to stabilize a pharmaceutical composition comprising azithromycin monohydrate. In addition, the stabilized azithromycin monohydrate compositions do not require an antioxidant.
    Type: Application
    Filed: July 27, 2007
    Publication date: April 24, 2008
    Inventors: Mohsen Sadatrezaei, Pablo Davila, Gary Barbera
  • Solubility of hydrophobic drugs with a compound having a carboxylic acid moiety
    Publication number: 20050249814
    Abstract: A pharmaceutical composition having improved solubility comprising a hydrophobic drug or pharmaceutically acceptable salt thereof and a compound having at least one carboxylic acid moiety, wherein the molar ratio of the compound having at least one carboxylic acid moiety to the hydrophobic drug or pharmaceutically acceptable salt thereof is from about 0.1:1 to about 25:1. The pharmaceutical composition exhibits rapid dissolution upon contact with physiological solvents, such as water, saliva or gastrointestinal fluids.
    Type: Application
    Filed: May 6, 2005
    Publication date: November 10, 2005
    Inventors: Gary Barbera, Chetan Doshi, Mahendra Patel, Pablo Davila, Satishkumar Patel
  • Modafinil compositions
    Publication number: 20050137264
    Abstract: A pharmaceutical composition comprising modafinil in the form of particles, wherein greater than 5% to about 50% of the cumulative total of the modafinil particles in the composition have a particle size greater than about 200 microns as determined by a U.S. Sieve No. 75. The present inventors have unexpectedly determined that the pharmaceutical compositions of the invention exhibit comparable stability, dissolution, and bioavailability as compared to Provigil® which is a commercially-available modafinil formulation.
    Type: Application
    Filed: December 22, 2003
    Publication date: June 23, 2005
    Inventors: Ashish Patel, Gary Barbera
  • Stabilized azithromycin composition
    Publication number: 20050101547
    Abstract: A stabilized azithromycin composition comprising azithromycin monohydrate, and about 5 to about 15 weight percent, based on the total weight of the composition, of water. The present inventors have unexpectedly determined that a certain amount of water is necessary to stabilize a pharmaceutical composition comprising azithromycin monohydrate. In addition, the stabilized azithromycin monohydrate compositions do not require an antioxidant.
    Type: Application
    Filed: November 6, 2003
    Publication date: May 12, 2005
    Inventors: Mohsen Sadatrezaei, Pablo Davila, Gary Barbera