Patents by Inventor Gary Brice
Gary Brice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20050208020Abstract: The inventive subject matter relates to an immunogenic composition and method of enhancing immunogenicity and protective immunity induced by any subunit or whole organism vaccine or combination of vaccines comprising administering to the subject a priming immunization preparation containing an antigen or fragment thereof, said preparation being selected from the group consisting of: a recombinant virus expression system; a recombinant protein antigen or a recombinant polypeptide; a synthetic peptide; a polynucleotide vector; a whole organism or extract and combinations thereof; and a boosting immunization of at least one alphavirus replicon containing an antigen or fragment thereof. The inventive subject matter further relates to an immunogenic composition and method of inducing an immune response that activates both cellular and humoral arms of the immune system.Type: ApplicationFiled: November 10, 2004Publication date: September 22, 2005Inventors: Denise Doolan, Gary Brice, Daniel Carucci, Kurt Kamrud, Jeffrey Chulay, Jonathan Smith
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Patent number: 6929738Abstract: A two stage hydrodesulfurizing process for producing low sulfur distillates. A distillate boiling range feedstock containing in excess of about 3,000 wppm sulfur is hydrodesulfurized in a first hydrodesulfurizing stage containing one or more reaction zones in the presence of hydrogen and a hydrodesulfurizing catalyst. The liquid product stream thereof is passed to a first separation stage wherein a vapor phase product stream and a liquid product stream are produced. The liquid product stream, which has a substantially lower sulfur and nitrogen content then the original feedstream is passed to a second hydrodesulfurizing stage also containing one or more reaction zones where it is reacted in the presence of hydrogen and a second hydrodesulfurizing catalyst at hydrodesulfurizing conditions. The catalyst in any one or more reaction zones is a bulk multimetallic catalyst comprised of at least one Group VIII non-noble metal and at least two Group VIB metals.Type: GrantFiled: January 14, 2000Date of Patent: August 16, 2005Assignee: ExxonMobil Research and Engineering CompanyInventors: Kenneth Llyod Riley, Darryl Patrick Klein, Zhiguo Hou, Stuart Leon Soled, Michael Charles Kerby, Gary Brice McVicker, Edward Stanley Ellis, Michele Sue Touvelle, Sabato Miseo
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Publication number: 20050031592Abstract: The inventive subject matter relates to an immunogenic composition and method of immunizing a subject against malarial disease comprising administering to the subject a priming immunization preparation comprising alphavirus replicons expressing a gene encoding a malarial antigen or combination of malarial antigens and subsequently administering to the subject a boosting immunization preparation comprising the malarial antigen(s) or an expression system containing the antigen(s). The inventive composition and methods result in a robust induction of humoral and cellular immune system responses, including CD8+, CD4+ and antibody responses.Type: ApplicationFiled: November 13, 2003Publication date: February 10, 2005Inventors: Denise Doolan, Gary Brice, Carlota Dobano-Lazaro, Jeffrey Chulay, Kurt Kamrud, Jonathan Smith
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Patent number: 6783663Abstract: A hydroprocessing process, comprising: contacting a feedstock, at hydrotreating conditions, with a bulk multimetallic catalyst comprised of at least one Group VIII non-noble metal and at least two Group VIB metals and wherein the ratio of Group VIB metal to Group VIII non-noble metal is from about 10:1 to about 1:10 to form a hydrotreated product.Type: GrantFiled: August 22, 2001Date of Patent: August 31, 2004Assignee: ExxonMobil Research and Engineering CompanyInventors: Kenneth Lloyd Riley, Darryl Patrick Klein, Zhiguo Hou, Stuart Leon Soled, Michael Charles Kerby, Gary Brice McVicker, Edward Stanley Ellis, Michele Sue Touvelle, Sabato Miseo
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Patent number: 6740228Abstract: Processes for reforming, and in particular aromatising, hydrocarbons from a petroleum source may be carried out by contacting the hydrocarbons with a catalyst of a zeolite KL impregnated with a metal promotor such as platinum, in which the zeolite crystals are of hockeypuck shape. The processes have a good yield and selectivity for the desired reformed products and the catalyst is stable, is associated with a low rate of coke formation, and has a long catalytically active life before regeneration is required.Type: GrantFiled: June 30, 1992Date of Patent: May 25, 2004Assignee: ExxonMobil Chemical Patents Inc.Inventors: Johannes Petrus Verduijn, Gary Brice McVicker, John Joseph Ziemiak
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Patent number: 6582590Abstract: Sulfur content of distillate feedstock, which is greater than 3,000 wppm, is reduced using multi-stage hydrodesulfurization by reacting the feestream in stages with reaction zone(s) containing bulk multimetallic catalyst comprised of Group VIII non-noble metal(s) and at least two group VIB metals. The ratio of Group VIB to Group VIII non-noble metals is 10:1 to 1:10.Type: GrantFiled: August 22, 2001Date of Patent: June 24, 2003Assignee: ExxonMobil Research and Engineering CompanyInventors: Kenneth Lloyd Riley, Darryl Patrick Klein, Zhiguo Hou, Stuart Leon Soled, Michael Charles Kerby, Gary Brice McVicker, Edward Stanley Ellis, Michele Sue Touvelle, Sabato Miseo
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Patent number: 6475374Abstract: A process for preparing a lubricating oil basestock having good low temperature properties. The process includes a first amorphous isomerization catalyst having a pore volume less than 0.99 ml/gm (H2O), an alumina content in the range of 30-50 wt % based on isomerization catalyst and an isoelectric point in the range of 4.5 to 6.5. The isomerization step is followed by a catalytic dewaxing step using an intermediate pore crystalline molecular sieve.Type: GrantFiled: September 15, 2000Date of Patent: November 5, 2002Assignee: ExxonMobil Research and Engineering CompanyInventors: Daniel Paul Leta, Stuart Leon Soled, Gary Brice McVicker, Sylvain Hantzer
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Patent number: 6383366Abstract: Waxy feeds are treated under hydroisomerization conditions to produce good yields of an isomerate product of high VI by using a silica-alumina based catalyst in which the silica-alumina has a pore volume less of 0.99 ml/gm (H2O), an alumina content in the range of 35 to 55 wt % and an isoelectric point in the range of 4.5 to 6.5. A lube fraction of the isomerate is dewaxed to provide a lube basestock of high VI. The silica-alumina may be modified with a rare earth oxide or yttria or boria or magnesia in which instance the modified catalyst has an isoelectric point greater than but no more than 2 points greater than base the silica-alumina.Type: GrantFiled: November 14, 2000Date of Patent: May 7, 2002Assignee: Exxon Research and Engineering CompanyInventors: Kenneth Lloyd Riley, William John Murphy, Ian Alfred Cody, Stuart Leon Soled, Gary Brice McVicker, Sabato Miseo
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Patent number: 5831138Abstract: The present invention is directed toward a catalyst composition comprising a catalyst prepared by a process comprising: (a) impregnating an oxide precursor selected from the group consisting of rare earth oxide precursors, yttria precursors and mixtures thereof, onto an inorganic refractory oxide support; (b) drying said support at a temperature of about 100.degree. to about 120.degree. C. followed by calcining said support at a temperature of about 400.degree. to about 600.degree. C.; and (c) compositing or depositing on said support of step (b), a catalyst precursor salt represented by (ML)(Mo.sub.y W.sub.1-y O.sub.4).sub.a wherein M comprises Cr and/or one or more divalent promoter metals selected from the group consisting of Mn, Fe, Co, Ni, Cu, Zn and mixtures thereof, wherein y is any value ranging from 0 to 1, and wherein L is one or more neutral, nitrogen-containing ligands at least one of which is a chelating polydentate ligand; a=1 when chromium is not one of the promoter metals and 0.5.ltoreq.a.Type: GrantFiled: August 15, 1997Date of Patent: November 3, 1998Assignee: Exxon Research and Engineering CompanyInventors: Teh Chung Ho, Stuart Leon Soled, Sabato Miseo, Gary Brice McVicker, Michel Daage, Viktor Buchholz
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Patent number: 5776849Abstract: The invention is directed a process for regenerating deactivated reforming catalysts comprising at least one Group VIII metal on zeolite L, preferably wherein the catalysts are extruded using a binder material such as alumina or silica. The process includes: a) coke burn at severe conditions to improve the accessibility of the Group VIII catalytic metal particles by transporting them to the outside of the zeolite microchannels; b) catalytic metal redispersion by wet oxychlorination with elemental chlorine and oxygen; c) stripping with a gas stream comprising oxygen and water at low pressure to remove as much residual chlorine as possible; and d) reduction of catalytic metals with hydrogen at low pressure. The process is particularly effective for recovering activity of catalysts which have been severely deactivated.Type: GrantFiled: September 9, 1992Date of Patent: July 7, 1998Assignee: Exxon Research & Engineering CompanyInventors: Shun Chong Fung, Yao-Jyh Robert Huang, John Francis Walsh, Gary Brice McVicker, Kenneth Ray Clem
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Patent number: 5756414Abstract: The present invention is a process for regenerating deactivated catalyst or redispersing catalytic metal in a fresh catalyst comprising at least one Group VIII catalytic metal, zeolite, an inert binder. The process comprises coke burn, hydrogen reduction, catalyst conditioning, oxychlorination, low pressure stripping, and low pressure final hydrogen reduction.Type: GrantFiled: September 4, 1992Date of Patent: May 26, 1998Assignee: Exxon Research and Engineering CompanyInventors: Yao-Jyh Robert Huang, Shun Chong Fung, Gary Brice McVicker, Jar-lin Kao, John Francis Walsh, Kenneth Ray Clem
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Patent number: 5728644Abstract: The present invention is directed toward a catalyst composition comprising a catalyst prepared by a process comprising: (a) impregnating an oxide precursor selected from the group consisting of rare earth oxide precursors, yttria precursors and mixtures thereof, onto an inorganic refractory oxide support; (b) drying said support at a temperature of about 100.degree. to about 120.degree. C. followed by calcining said support at a temperature of about 400.degree. to about 600.degree. C.; and (c) compositing or depositing on said support of step (b), a catalyst precursor salt represented by (ML)(Mo.sub.y W.sub.1-y O.sub.4).sub.a wherein M comprises Cr and/or one or more divalent promoter metals selected from the group consisting of Mn, Fe, Co, Ni, Cu, Zn and mixtures thereof, wherein y is any value ranging from 0 to 1, and wherein L is one or more neutral, nitrogen-containing ligands at least one of which is a chelating polydentate ligand; a=1 when chromium is not one of the promoter metals and 0.5.ltoreq.a.Type: GrantFiled: September 5, 1995Date of Patent: March 17, 1998Assignee: Exxon Research and Engineering CompanyInventors: Teh Chung Ho, Stuart Leon Soled, Sabato Miseo, Gary Brice Mc Vicker, Michel Daage, Viktor Buchholz
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Patent number: 5648577Abstract: The present invention is directed toward a catalyst composition prepared by a process comprising: (a) impregnating an oxide precursor selected from the group consisting of rare earth oxide precursors, yttria precursors and mixtures thereof, onto an inorganic refractory oxide support; (b) drying said support at a temperature of about 100.degree. to about 120.degree. C. followed by calcining said support at a temperature of about 400.degree. to about 600.degree. C.; and (c) compositing or depositing on said support of step (b), a catalyst precursor salt represented by (ML)(Mo.sub.y W.sub.1-y O.sub.4).sub.a wherein M comprises Cr and/or one or more divalent promoter metals selected from the group consisting of Mn, Fe, Co, Ni, Cu, Zn and mixtures thereof, wherein y is any value ranging from 0 to 1, and wherein L is one or more neutral, nitrogen-containing ligands at least one of which is a chelating polydentate ligand; a=1 when chromium is not one of the promoter metals and 0.5.ltoreq.a.ltoreq.Type: GrantFiled: June 2, 1995Date of Patent: July 15, 1997Assignee: Exxon Research and Engineering CompanyInventors: Teh Chung Ho, Stuart Leon Soled, Sabato Miseo, Gary Brice McVicker, Michel Daage, Viktor Buchholz