Patents by Inventor Gary Brownlee

Gary Brownlee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090220497
    Abstract: The present invention relates generally to treatment and prophylactic protocols for cellular diseases or disorders, such as diseases and disorders associated with abnormal cellular proliferation. More particularly, the present invention provides compositions comprising therapeutic antibodies and hyaluronan and their use in the treatment or prophylaxis of cellular diseases and disorders.
    Type: Application
    Filed: September 4, 2006
    Publication date: September 3, 2009
    Inventors: Tracey J. Brown, Gary Brownlee
  • Publication number: 20090068183
    Abstract: The present invention is directed to compounds, agents, pharmaceutically active agents, medicaments, therapeutics, actives, drugs and the like which specifically target a portion of the HAS molecule which is accessible to the extracellular environment in a first form of a cell but which is not accessible to the extracellular environment in another form of or in a transformed cell form the same or related cell. In particular, the present invention provides compounds which target a portion of HAS which is accessible to the extracellular environment in malignant or inflammatory or proliferative cells but which portion is not accessible to the external environment in “normal” cells. A “normal” cell in this instance is a non-malignant, inflammatory or proliferative cell.
    Type: Application
    Filed: March 23, 2007
    Publication date: March 12, 2009
    Applicant: Alchemia Oncology Limited
    Inventors: Tracey J. Brown, Gary Brownlee
  • Publication number: 20070286856
    Abstract: The present invention provides compositions and methods for modulating the expression of Hyaluronan (HA). In particular, this invention relates to compounds, which hybridize with nucleic acid molecules encoding hyaluronan synthase (HAS), particularly HAS isoforms HAS1, HAS2 and HAS3. These compounds may range in size from oligonucleotides to full length sequences. Such compounds are exemplified to modulate proliferation, such as cancer and inflammatory disorders, such as arthritis. It will be understood, however, that the compounds can be used for any other condition in which HA is involved.
    Type: Application
    Filed: October 11, 2004
    Publication date: December 13, 2007
    Inventors: Tracey Brown, Gary Brownlee